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Browse our BCL2L1 Proteins (BCL2L1)

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BCL2-Like 1 Proteins (BCL2L1)
On are 19 BCL2-Like 1 (BCL2L1) Proteins from 9 different suppliers available. Additionally we are shipping BCL2L1 Antibodies (379) and BCL2L1 Kits (22) and many more products for this protein. A total of 444 BCL2L1 products are currently listed.
Bcl(X)L, bcl-X, bcl-x(l), bcl-xl, BCL-XL/S, Bcl-Xs, Bcl2l, BCL2L1, Bclx, BCLXL, BCLXS, PPP1R52, xR11
list all proteins Gene Name GeneID UniProt
BCL2L1 60480  
BCL2L1 598 Q07817
BCL2L1 24888 P53563

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BCL2L1 Proteins (BCL2L1) by Origin

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Top referenced BCL2L1 Proteins

  1. Human BCL2L1 Protein expressed in Escherichia coli (E. coli) - ABIN2180638 : Terrano, Upreti, Chambers: Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis. in Molecular and cellular biology 2010 (PubMed)

  2. Mouse (Murine) BCL2L1 Protein expressed in Escherichia coli (E. coli) - ABIN2007143 : Muchmore, Sattler, Liang, Meadows, Harlan, Yoon, Nettesheim, Chang, Thompson, Wong, Ng, Fesik: X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. in Nature 1996 (PubMed)

More Proteins for BCL2L1 Interaction Partners

Mouse (Murine) BCL2-Like 1 (BCL2L1) interaction partners

  1. MLF1 (show MLF1 Proteins) is negatively regulated by 14-3-3 (show YWHAQ Proteins) via binding to, and blocking, MLF1 (show MLF1 Proteins)'s Bcl-2 (show BCL2 Proteins) homology domain 3 and thereby preventing Bcl-XL from associating with MLF1 (show MLF1 Proteins).

  2. Genetic and pharmacological inhibition of BCL-W (show BCL2L2 Proteins) and BCL-XL causes directed elimination of senescent cells.

  3. Valproic acid sensitized TRAIL-resistant papillary thyroid carcinoma cells to apoptotic cell death through involvement of Nrf2 (show NFE2L2 Proteins) and Bcl-xL.

  4. The influence of chronic ethanol consumption on the expression of the Bdnf (show BDNF Proteins), Bax (show BAX Proteins), Bcl-xL, and CASP3 (show CASP3 Proteins) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.

  5. despite its role in Bax (show BAX Proteins) inhibition, Bcl-xL also primes mitochondria to permeabilization and cytochrome c (show CYCS Proteins) release.

  6. These findings indicate that eosinophil survival is largely regulated by betac chain-induced NF-kappaB (show NFKB1 Proteins) activation and subsequent induction of Bcl-x

  7. these data indicate that beta-cell apoptosis is, in part, attributable to the modulation of 5'SS selection in the Bcl-x pre-mRNA by bioactive lipids modulated by iPLA2beta (show PLA2G6 Proteins).

  8. only loss of both Bclx alleles markedly forestalled tumorigenesis, loss of a single Bim (show BCL2L11 Proteins) allele overcame this blockade.

  9. analysis of the role of BCL-XL or MCL-1 (show MCL1 Proteins) in the development and sustained growth of thymic lymphoma elicited by loss of p53 (show TP53 Proteins) reveals that only MCL-1 (show MCL1 Proteins) is critical

  10. cell death is C/EBP homologous protein (CHOP (show DDIT3 Proteins))-dependent, connecting these events to the UPR. Thus plasma cell differentiation proceeds through a Bcl-xL-dependent intermediate.

Human BCL2-Like 1 (BCL2L1) interaction partners

  1. Genetic and pharmacological inhibition of BCL-W (show BCL2L2 Proteins) and BCL-XL causes directed elimination of senescent cells.

  2. Data suggest that regulation of Bax (show BAX Proteins) stability and transport between cytosol and mitochondria is more tightly regulated by Bcl-xL/BCL2L1 when Bax (show BAX Proteins) has been phosphorylated at Ser184 by AKT1 (show AKT1 Proteins); experiments involved expression in haploid yeast strains.

  3. miR (show MLXIP Proteins)-133a and miR (show MLXIP Proteins)-326 downregulate the mRNA expression of Bcl-xl in HepG2 cells.

  4. Bcl-xL is a key factor in polyploidization resistance in acute myeloid leukemia (show BCL11A Proteins)

  5. This study lends new molecular insights into understanding the binding specificity of BH3 ligands to BclXL with important consequences on the design of novel anticancer drugs.

  6. TCERG1 sensitizes a cell to apoptotic agents, thus promoting apoptosis by regulating the alternative splicing of both the Bcl-x and Fas/CD95 (show FAS Proteins) genes.

  7. Data show that JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) signaling inhibition is potentiated by Bcl-xL (B-cell lymphoma-extra large) blockade in interleukin 2 (IL-2 (show IL2 Proteins)) dependent adult T-cell leukemia cells.

  8. Data suggest BCL2-like 1 protein (BCL2L1) and deleted in liver cancer 1 protein (DLC1) as potential druggable targets for specific subsets of gastric cancer (GC) cases.

  9. CD40 (show CD40 Proteins) signaling led to sustained ERK1/2 activation and up-regulation of Bcl-xL in BCR (show BCR Proteins)-primed HF1A3 germinal center B cells.[BCR (show BCR Proteins)]

  10. Lewis y leads to inhibition of apoptosis and enhancement of CAM (show CALM1 Proteins)-DR by activation of the FAK (show PTK2 Proteins) signaling pathway and upregulation of Bcl-2 (show BCL2 Proteins)/Bcl-XL expression in ovarian cancer cell lines.

Pig (Porcine) BCL2-Like 1 (BCL2L1) interaction partners

  1. interleukin-6 (show IL6 Proteins), endothelin ET-1 (show EDN1 Proteins), and apoptotic Bak (show BAK1 Proteins) and Bcl-XL genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  2. Bcl-xL was significantly decreased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis

  3. CONCLUSION(S): (1) Apoptosis is involved in follicular atresia; (2) Bcl-2 (show BCL2 Proteins) is induced by warm ischemia; and (3) cryopreservation insult does not alter the apoptotic signals with short tissue preparation time.

  4. Bcl-Xl deamidation and methylation has a role in protein isoaspartate methyltransferase prevention of apoptosis induced by oxidative stress in endothelial cells

  5. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (show TNF Proteins), IL-6 (show IL6 Proteins), IL-12p40, IL-1beta (show IL1B Proteins), and resulted in increased expression of the apoptosis initiator caspase-8 (show CASP8 Proteins) and bcl2L1.

Cow (Bovine) BCL2-Like 1 (BCL2L1) interaction partners

  1. amplification and characterization of partial regions of exons 2 and 3 of the bovine BCL2L1 gene

  2. Data show that Bcl-x(L) expression is increased in the pulmonary artery undergoing chronic pulmonary vascular remodeling.

Rabbit BCL2-Like 1 (BCL2L1) interaction partners

  1. This study leads to conclude that BCLXL peak expression at the zygotic genome activation phase may be a requirement for embryo development

  2. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2L1 transcripts and protein depending on luteal stage.

Xenopus laevis BCL2-Like 1 (BCL2L1) interaction partners

  1. repression of radiation-induced apoptosis by overexpression of Bcl-xL during embryonic development depends upon the timing of its expression and post-translational events that enable the protein to become effective

BCL2L1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.

Alternative names and synonyms associated with BCL2L1

  • BCL2-like 1 (bcl2l1)
  • BCL2-like 1 (BCL2L1)
  • BCL2-like 1 (LOC100224900)
  • transgene insertion 2, Craig B Thompson (Tg(BCL2L1)2Cbt)
  • BCL2-like 1 (Bcl2l1)
  • Bcl2-like 1 (Bcl2l1)
  • Bcl(X)L protein
  • bcl-X protein
  • bcl-x(l) protein
  • bcl-xl protein
  • BCL-XL/S protein
  • Bcl-Xs protein
  • Bcl2l protein
  • BCL2L1 protein
  • Bclx protein
  • BCLXL protein
  • BCLXS protein
  • PPP1R52 protein
  • xR11 protein

Protein level used designations for BCL2-Like 1 Proteins (BCL2L1)

BCL2-like 1 , apoptosis regulator Bcl-X , bcl-2-like protein 1 , protein phosphatase 1, regulatory subunit 52 , B-cell leukemia/lymphoma x , anti-apoptosis regulatory protein , bcl2-L-1 , B cell lymphoma 2 like , B cell lymphoma like X , anti-apoptotic Bcl-xL , BCL2-like protein 1 , Bcl-X , BCLX protein , apoptosis regulator R11

447991 Xenopus (Silurana) tropicalis
458156 Pan troglodytes
100224900 Taeniopygia guttata
60480 Mus musculus
598 Homo sapiens
12048 Mus musculus
24888 Rattus norvegicus
397536 Sus scrofa
403618 Canis lupus familiaris
282152 Bos taurus
100008875 Oryctolagus cuniculus
493701 Felis catus
443061 Ovis aries
373954 Gallus gallus
398251 Xenopus laevis
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