BCL2L1 Protein (His tag)
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- Target See all BCL2L1 Proteins
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BCL2L1 protein is labelled with His tag.
- Purpose
- Recombinant Human BCL2L1/Bcl-XL Protein (His Tag)
- Sequence
- Met1-Arg212
- Characteristics
- Recombinant Human BCL2L1 is produced by our E.coli expression system and the target gene encoding Met1-Arg212 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BCL2L1 Protein
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BCL2-Like 1 (BCL2L1) (AA 1-209) protein (His tag)
BCL2L1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
BCL2-Like 1 (BCL2L1) (AA 1-212) protein (His tag)BCL2L1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
BCL2-Like 1 (BCL2L1) (AA 1-233) protein (GST tag)BCL2L1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Like 1 (BCL2L1) (AA 1-212) (Active) protein (His tag)BCL2L1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
BCL2-Like 1 (BCL2L1) (AA 1-233) protein (Strep Tag)Crystallography grade BCL2L1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
BCL2-Like 1 (BCL2L1) (AA 1-233) protein (Strep Tag)Crystallography grade BCL2L1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 50 mM KCl, 20 % Glycerol, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Alternative Name
- BCL2L1/Bcl-XL (BCL2L1 Products)
- Synonyms
- BCL-XL/S Protein, BCL2L Protein, BCLX Protein, BCLXL Protein, BCLXS Protein, Bcl-X Protein, PPP1R52 Protein, bcl-xL Protein, bcl-xS Protein, Bcl(X)L Protein, Bcl-XL Protein, Bcl-Xs Protein, Bcl2l Protein, BclX Protein, bcl-x Protein, Bcl-xl Protein, Bclx Protein, bcl-X Protein, Bcl-xL Protein, BCL-XL Protein, BCL2L1 Protein, bcl-XL Protein, bcl-x(l) Protein, bcl-xl/s Protein, bcl-xs Protein, bcl2l Protein, bclx Protein, bclxl Protein, xR11 Protein, bcl-xl Protein, blp1 Protein, cb1021 Protein, zfBLP1 Protein, BCL2 like 1 Protein, BCL2-like 1 Protein, Bcl2-like 1 Protein, BCL2-like 1 L homeolog Protein, bcl2-like 1 Protein, BCL2L1 Protein, Bcl2l1 Protein, bcl2l1 Protein, bcl2l1.L Protein
- Background
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Background: Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.
Synonym: Bcl-2-Like Protein 1, Bcl2-L-1, Apoptosis Regulator Bcl-X, Bcl-X,bcl-xL,BCL-XL/S,bcl-xS,BCL2L,BCLX,BCLXL,BCLXS,PPP1R52
- Molecular Weight
- 24.85 kDa
- UniProt
- Q07817
- Pathways
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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