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Browse our anti-BIRC3 (BIRC3) Antibodies

Full name:
anti-Baculoviral IAP Repeat Containing 3 Antibodies (BIRC3)
On are 160 Baculoviral IAP Repeat Containing 3 (BIRC3) Antibodies from 20 different suppliers available. Additionally we are shipping BIRC3 Proteins (8) and BIRC3 Kits (4) and many more products for this protein. A total of 189 BIRC3 products are currently listed.
AIP1, Api1, Api2, AW107670, AW146227, Birc2, Birc3, c-IAP2, cIAP-1, cIAP-2, cIAP1, cIAP2, HAIP1, HIAP1, HIAP2, IAP1, IAP2, MALT2, mcIAP1, MIAP1, MIAP2, MIHB, MIHC, rIAP1, RNF48, RNF49
list all antibodies Gene Name GeneID UniProt
BIRC3 330 Q13489
BIRC3 11797 Q62210
BIRC3 60371  

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anti-Human BIRC3 Antibodies:

anti-Mouse (Murine) BIRC3 Antibodies:

anti-Rat (Rattus) BIRC3 Antibodies:

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Top referenced anti-BIRC3 Antibodies

  1. Human Monoclonal BIRC3 Primary Antibody for IP, WB - ABIN967366 : Deveraux, Reed: IAP family proteins--suppressors of apoptosis. in Genes & development 1999 (PubMed)
    Show all 7 references for ABIN967366

  2. Human Polyclonal BIRC3 Primary Antibody for IHC (p), WB - ABIN390069 : Wang, Wang, Evers: Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B. in The Journal of biological chemistry 2003 (PubMed)
    Show all 7 references for ABIN390069

  3. Human Polyclonal BIRC3 Primary Antibody for IF, IHC (p) - ABIN657941 : Petersen, Peyton, Minna, Wang: Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 2 references for ABIN657941

  4. Human Polyclonal BIRC3 Primary Antibody for ICC, IF - ABIN439961 : Guicciardi, Mott, Bronk, Kurita, Fingas, Gores: Cellular inhibitor of apoptosis 1 (cIAP-1) degradation by caspase 8 during TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. in Experimental cell research 2010 (PubMed)
    Show all 2 references for ABIN439961

  5. Human Polyclonal BIRC3 Primary Antibody for ELISA, WB - ABIN4298724 : Zheng, Kabaleeswaran, Wang, Cheng, Wu: Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation. in Molecular cell 2010 (PubMed)

  6. Human Polyclonal BIRC3 Primary Antibody for IHC (p), IHC - ABIN151193 : Shen, Esnault, Schinzel, Borner, Malter: The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation. in Nature immunology 2009 (PubMed)

More Antibodies against BIRC3 Interaction Partners

Human Baculoviral IAP Repeat Containing 3 (BIRC3) interaction partners

  1. Study demonstrate that BIRC3 expression increases secondary to acquisition of temozolomide TMZ and irradiation resistance in glioblastoma.

  2. High BIRC3 expression is associated with pancreatic cancer.

  3. Network analysis identified BIRC3 as pathogenic gene in childhood asthma.

  4. The clinical impact of small subclones harboring NOTCH1 (show NOTCH1 Antibodies), SF3B1 (show SF3B2 Antibodies), or BIRC3 mutations in chronic lymphocytic leukemia patients appears to be less pronounced than that of small TP53 (show TP53 Antibodies) mutated subclones.

  5. cIAP1 (show BIRC2 Antibodies) and cIAP2 mediate BCL10 (show BCL10 Antibodies) ubiquitination essential for BCR (show BCR Antibodies)-dependent NF-kB activity in the ABC (show ABCB6 Antibodies) subtype of DLBCL. cIAP1 (show BIRC2 Antibodies)/2 attach K63-linked polyubiquitin (show UBB Antibodies) chains on themselves and on BCL10 (show BCL10 Antibodies), recruiting IKK (show CHUK Antibodies) and LUBAC essential for IKK (show CHUK Antibodies) activation.

  6. Data indicate that Smac/DIABLO (show DIABLO Antibodies) showed an inverse correlation with inhibitor of apoptosis proteins XIAP (show XIAP Antibodies), cIAP-1 (show BIRC2 Antibodies) and cIAP-2.

  7. cIAP2 is upregulated in regenerative epithelial cells both in ulcerative colitis and in experimental intestinal wounds. Inhibition of cIAP2 decreases wound healing in vitro possibly through inhibition of migration. [review]

  8. LapR cells possessed increased levels of 2 of the inhibitors of apoptosis (IAPs), survivin (show BIRC5 Antibodies) and c-IAP-2, which are reported to block caspase (show CASP3 Antibodies) activation downstream of cytosolic cytochrome C (show CYCS Antibodies) release.

  9. API2-MALT1 induces paracaspase-mediated cleavage of the tumour suppressor protein LIMA1 (show LIMA1 Antibodies).

  10. this study candidates BIRC3 as one of the potentially useful predictive marker for discriminating patients with oesophageal and oesophagogastric junction adenocarcinoma who will most likely benefit from preoperative chemoradiotherapy.

Mouse (Murine) Baculoviral IAP Repeat Containing 3 (BIRC3) interaction partners

  1. These findings reveal a novel mechanism that endotoxin tolerance reprograms mitogen-activated protein kinase (show MAPK1 Antibodies) signaling by suppressing Pellino 1 (show PELI1 Antibodies)-mediated K63-linked ubiquitination of cIAP2, K48-linked ubiquitination, and degradation of TRAF3 (show TRAF3 Antibodies).

  2. Birc3-deficient mice are resistant to azoxymethane-sodium dodecyl sulfate-induced colitis-associated colorectal cancer.

  3. c-IAP (show ALPI Antibodies) ubiquitin protein ligase (show UBE2K Antibodies) activity is required for 4-1BB (show TNFRSF9 Antibodies) signaling and CD8 (show CD8A Antibodies)(+) memory T-cell survival.

  4. Induction of cIAP2 expression upon microglia activation prevents the conversion of caspase-3 p19 subunit to p17 subunit.

  5. Results identify IGF2BP1 (show B4GALNT2 Antibodies) as a critical translational regulator of cIAP1 (show BIRC2 Antibodies)-mediated apoptotic resistance in rhabdomyosarcoma.

  6. we show that cIAP1 (show BIRC2 Antibodies) regulates TNF (show TNF Antibodies)-induced actin cytoskeleton reorganization through a cdc42 (show CDC42 Antibodies)-dependentpathway

  7. Identify xIAP (show XIAP Antibodies) and cIAP1 (show BIRC2 Antibodies) as molecular targets of ceramide and show ceramide analog LCL85 is an effective sensitizer in overcoming resistance of metastatic colon and breast cancers to apoptosis induction to suppress metastasis in vivo.

  8. cIAP2 (Birc3)-dependent antagonism of RIPK3 (show RIPK3 Antibodies)-mediated programmed necrosis critically protects the host from influenza infection through maintenance of pulmonary tissue homeostasis.

  9. cIAP-2 protects cardiac fibroblasts from oxidative damage: an obligate regulatory role for ERK1/2 (show MAPK1/3 Antibodies) MAPK (show MAPK1 Antibodies) and NF-kappaB (show NFKB1 Antibodies).

  10. these results show that the loss of cIAP1 (show BIRC2 Antibodies) protects skeletal muscle from the degenerative pathology resulting from systemic loss of dystrophin (show DMD Antibodies).

BIRC3 Antigen Profile

Antigen Summary

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Alternative names and synonyms associated with BIRC3

  • baculoviral IAP repeat-containing 3 (BIRC3) antibody
  • inhibitor of apoptosis protein-2 (OpmnVgp074) antibody
  • baculoviral IAP repeat containing 3 (BIRC3) antibody
  • baculoviral IAP repeat-containing 2 (Birc2) antibody
  • baculoviral IAP repeat-containing 3 (Birc3) antibody
  • AIP1 antibody
  • Api1 antibody
  • Api2 antibody
  • AW107670 antibody
  • AW146227 antibody
  • Birc2 antibody
  • Birc3 antibody
  • c-IAP2 antibody
  • cIAP-1 antibody
  • cIAP-2 antibody
  • cIAP1 antibody
  • cIAP2 antibody
  • HAIP1 antibody
  • HIAP1 antibody
  • HIAP2 antibody
  • IAP1 antibody
  • IAP2 antibody
  • MALT2 antibody
  • mcIAP1 antibody
  • MIAP1 antibody
  • MIAP2 antibody
  • MIHB antibody
  • MIHC antibody
  • rIAP1 antibody
  • RNF48 antibody
  • RNF49 antibody

Protein level used designations for BIRC3

baculoviral IAP repeat-containing 3 , baculoviral IAP repeat-containing protein 3-like , inhibitor of apoptosis protein-2 , IAP homolog C , IAP-1 , RING finger protein 49 , TNFR2-TRAF signaling complex protein , TNFR2-TRAF-signaling complex protein 1 , apoptosis inhibitor 2 , baculoviral IAP repeat-containing protein 3 , inhibitor of apoptosis protein 1 , mammalian IAP homolog C , IAP-2 , baculoviral IAP repeat-containing protein 2 , inhibitor of apoptosis protein 2 , mIAP-2 , inhibitor of apoptosis protein , apoptosis inhibitor 1 , baculoviral IAP repeat-containing 2 , mIAP-1

100399118 Callithrix jacchus
912069 Orgyia pseudotsugata multiple nucleopolyhedrovirus
330 Homo sapiens
489433 Canis lupus familiaris
11797 Mus musculus
60371 Rattus norvegicus
11796 Mus musculus
78971 Rattus norvegicus
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