BIRC3 antibody (Internal Region)

Catalog No. ABIN571244

The Goat Polyclonal anti-BIRC3 antibody is suitable to detect BIRC3 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for BIRC3 antibody (Internal Region) (ABIN571244)

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This BIRC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-BIRC3 Antibody

Binding Specificity: Internal Region

Purpose: BIRC3 (aa 109 -118)

Sequence: SQPTFPSSVT

Specificity: Reported variants represent identical protein: NP_892007.1, NP_001156.1

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: C-SQPTFPSSVT

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Tonsil. Recommended concentration: 5 μg/mL.

Western Blot: Approx 70 kDa band observed in lysates of cell line HeLa (calculated MW of 68.4 kDa according to NP_001156.1). Recommended concentration: 0.1-0.3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for BIRC3

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Alternative Name: BIRC3

Background: BIRC3, baculoviral IAP repeat-containing 3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2, TNFR2-TRAF signaling complex protein, apoptosis inhibitor 2, baculoviral IAP repeat-containing protein 3, inhibitor of apoptosis protein 1, mammalian

Gene ID: 330

NCBI Accession: NP_001156

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades