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Browse our CAPN2 (CAPN2) ELISA Kits

Full name:
Calpain 2, (M/II) Large Subunit ELISA Kits (CAPN2)
On www.antibodies-online.com are 15 Calpain 2, (M/II) Large Subunit (CAPN2) ELISA Kits from 6 different suppliers available. Additionally we are shipping CAPN2 Antibodies (28) and CAPN2 Proteins (5) and many more products for this protein. A total of 49 CAPN2 products are currently listed.
Synonyms:
AI326419, CANP2, CANP 2, CANPL2, CANPml, Capa-2, Capa2, m-calpain, m-calpin, mCANP
list all ELISA KIts Gene Name GeneID UniProt
CAPN2 12334 O08529
CAPN2 824 P17655
CAPN2 29154 Q07009

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More ELISA Kits for CAPN2 Interaction Partners

Mouse (Murine) Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.

  2. LOX-1 (show OLR1 ELISA Kits) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (show CAPN1 ELISA Kits) and -2.

  3. Dicer is predominantly (show CA2 ELISA Kits) a Capn2 substrate. Dicer levels were altered in platelets from diabetic mice due to the cleavage (show DICER1 ELISA Kits) of the enzyme by calpain, resulting in loss of function.

  4. Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle m-calpain/Capn2 and u-calpain/Capn1 expression, and down-regulates muscle calpastatin expression.

  5. Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 (show CAPN1 ELISA Kits) deficient mice.

  6. Calpain-mediated proteolysis of tropomodulin isoforms TMOD1 (show TMOD1 ELISA Kits) and TMOD4 (show TMOD4 ELISA Kits) leads to thin filament elongation in dystrophic skeletal muscle.

  7. extrasynaptic NMDAR (show GRIN1 ELISA Kits)-coupled m-calpain activation is neurodegenerative

  8. Down-regulated expression of calpain-2 or talin-1, or pharmacological interference with calpain action, did not affect toxin binding but reduced endocytosis and increased the survival of cells exposed to anthrax lethal toxin.

  9. The carboxyl tail of alpha-actinin-4 (show ACTN4 ELISA Kits) regulates its susceptibility to m-calpain and thus functions in cell migration and spreading.

  10. Calpain-2 was required for FFA-induced expression of CHOP (show DDIT3 ELISA Kits) and activation of caspase-12 (show CASP12 ELISA Kits) and caspase-3 (show CASP3 ELISA Kits), thus promoting cell apoptosis in beta-TC3 cells.

Human Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.

  2. Taken together, our results demonstrated the deregulation of GAS2 (show GAS2 ELISA Kits) in both AML (show RUNX1 ELISA Kits) and ALL and the requirement of GAS2 (show GAS2 ELISA Kits)-Calpain2 axis for the growth of leukemic cells.

  3. The combination of Ca2 (show CA2 ELISA Kits)+ and ionomycin was required to activate calpain 2, resulting in the further degradation of Dicer (show DICER1 ELISA Kits) and the appearance of a degradation product similar to that detected in platelets from some diabetic individuals.

  4. In a transgenic mouse model, hypoxia-triggered m-calpain activation is involved in endoplasmic reticulum stress-mediated Alzheimer's disease pathogenesis.

  5. Small interfering RNA (siRNA)-mediated silencing of m-calpain expression significantly suppressed the adhesive, migrative and invasive potentials of human hepatoma cells.

  6. The data reveal that hGAAP is a novel regulator of focal adhesion dynamics, cell adhesion, and migration by controlling localized Ca(2 (show CA2 ELISA Kits)+)-dependent activation of calpain 2.

  7. The carboxyl tail of alpha-actinin-4 (show ACTN4 ELISA Kits) regulates its susceptibility to m-calpain and thus functions in cell migration and spreading.

  8. data demonstrate that GSK-3beta plays an important role in regulating tRXRalpha production by calpain II in cancer cells

  9. alpha-II spectrin (show SPTAN1 ELISA Kits) was drastically accumulated in infected T cells derived from adult T-cell leukemia patients, whereas its digestive protease calpain-2 (CAN2) was significantly downregulated.

  10. The results suggest that calpain-2 and calpastatin (show CAST ELISA Kits) expression is important in pancreatic cancers, influencing disease progression

Cow (Bovine) Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. m- and micro-calpain immunosignals in the cytoplasm both along the Z disk/I band regions and in the form of intracellular stores.

  2. The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain/HhaI, and UCP-3 (show UCP3 ELISA Kits)/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.

  3. The cleavage of NCX1 (show SLC8A1 ELISA Kits) by m-calpain in the caveolae vesicles may be interpreted as an important mechanism of Ca(2 (show CA2 ELISA Kits)+) overload

  4. characteristic properties of ER membrane m-calpain (MCp (show CD46 ELISA Kits)), calpastatins and lumen m-calpain (LCp (show KLHDC2 ELISA Kits)) and a brief comparative study between MCp (show CD46 ELISA Kits) and LCp (show KLHDC2 ELISA Kits)

Pig (Porcine) Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. Calpain-2 plays an important role in lung endothelial cell migration and proliferation.

  2. The Decreased expression of calpain 2 mRNA during development is highly correlated with muscle protein accumulation in neonatal Sus scrofa.

CAPN2 Antigen Profile

Antigen Summary

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CAPN2

  • calpain 2 (Capn2) Elisa Kit
  • calpain 2, (m/II) large subunit (CAPN2) Elisa Kit
  • calpain 2, (m/II) large subunit (Capn2) Elisa Kit
  • AI326419 Elisa Kit
  • CANP2 Elisa Kit
  • CANP 2 Elisa Kit
  • CANPL2 Elisa Kit
  • CANPml Elisa Kit
  • Capa-2 Elisa Kit
  • Capa2 Elisa Kit
  • m-calpain Elisa Kit
  • m-calpin Elisa Kit
  • mCANP Elisa Kit

Protein level used designations for CAPN2

80 kDa M-calpain subunit , CALP80 , CANP 2 , calcium-activated neutral proteinase 2 , calpain M-type , calpain-2 catalytic subunit , calpain-2 large subunit , cysteine proteinase , m-calpain 80 kDa large subunit , m-calpain large subunit , millimolar-calpain , M-calpain , calpain 2, large [catalytic] subunit , calpain 2, large subunit , calpain large polypeptide L2 , calpain, large polypeptide L2 , mCL , calpain II

GENE ID SPECIES
12334 Mus musculus
824 Homo sapiens
29154 Rattus norvegicus
281662 Bos taurus
395963 Gallus gallus
397393 Sus scrofa
100009092 Oryctolagus cuniculus
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