Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human Caspase 7 Protein expressed in Escherichia coli (E. coli) - ABIN413137
Chen, Xia, Fang, Hawke, Lu: Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis. in Molecular and cellular biology 2009
Show all 7 references for ABIN413137
Caspase 7 Protein expressed in Escherichia coli (E. coli) - ABIN925121
Stennicke, Salvesen: Biochemical characteristics of caspases-3, -6, -7, and -8. in The Journal of biological chemistry 1997
Caspase 7 has a nonapoptic function that participates in normal spermatogenesis, but also displays apoptotic function in spermatogenic dysfunction.
Our study shows for the first time activated caspase-7 in hair follicles and mast cells and indicates its non-apoptotic roles in the skin.
The results reveal that executioner caspases can modulate heart's cellularity and maturation during development, contributing novel information about caspase (show CASP3 Proteins) biology and heart development.
Optic nerve crush activated caspase-7 in retinal ganglion cells followed by cell death. Knockout of caspase-7 partially and significantly protected against ON injury-induced RGC loss.
Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 (show CASP3 Proteins) and -7-dependent.
genetic loss of caspase-7 promotes solar-simulated light-induced skin carcinogenesis by blocking caspase-7-mediated cleavage of keratin-17 (show KRT17 Proteins).
Interleukin-1beta enhances FasL (show FASL Proteins)-induced caspase-3 (show CASP3 Proteins)/-7 activity without increasing apoptosis in primary mouse hepatocytes
In vitro, with application of specific inhibitors and siRNA, AND-induced apoptosis was proven through ROS (show ROS1 Proteins)-ERK (show EPHB2 Proteins)-P53 (show TP53 Proteins)-caspase 7-PARP (show PARP1 Proteins) signaling pathway
The scotopic electroretinography demonstrated that the ablation of the CASP7 in T17M RHO retina leads to significant preservation of the function of photoreceptors compared to controls.
Polyglutamine oligomers augmented at the endoplasmic reticulum (ER) induce insertion of Bax (show BAX Proteins) into the ER membrane, thereby activating caspase-7.
Thymoquinone-triggered apoptosis was substantiated by up-regulation of the executioner caspase-3 (show CASP3 Proteins) and caspase-7, as well as cleavage of the death substrate poly(ADP-ribose)polymerase (show PARP1 Proteins).
Casp3 (show CASP3 Proteins)/7-Instructed Intracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging of Tumor Apoptosis.
Low expression of CASP7 is associated with non-small cell lung cancer.
this report suggests a novel finding that cellular signaling caspase 3 (show CASP3 Proteins)/7-PKCdelta (show PKCd Proteins)-Akt (show AKT1 Proteins)/p38 MAPK (show MAPK14 Proteins) is crucial to the repopulation in Panc1 cells after radiotherapy.
18)F-C-SNAT (show AANAT Proteins) has significantly increased tumor uptake and significantly increased tumor-to-muscle ratio in a preclinical mouse model of tumor therapy.
Centipedegrass extract induces apoptosis through the activation of caspases and the downregulation of PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) and MAPK (show MAPK1 Proteins) phosphorylation in leukemia cells.
Phosphorylate caspase-7 bu Src (show SRC Proteins) at multiple tyrosine sites enhanced its cellular apoptotic effect.
Potentially functional polymorphisms in the CASP7 gene contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population.
Data show that sangivamycin induced the apoptosis of primary effusion lymphoma (PEL) cells by activating caspase-7 and -9 and suppressed the phosphorylation of Erk1/2 and Akt (show AKT1 Proteins), thus inhibiting activation of the proteins.
Inhibition of activated CASP7 by X-linked inhibitor of apoptosis protein (show XIAP Proteins) is a potential mechanism by which apoptosis is prevented in those cancer cells deficient in casp3 (show CASP3 Proteins).
mRNA expression of Bax (show BAX Proteins), Bcl-2 (show BCL2 Proteins), caspase-3 (show CASP3 Proteins) and-7 cannot be used as a reliable apoptosis detection method.
the capacity for blastocysts to undergo further development is related to degree of group II caspase (show CASP3 Proteins) activity
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, caspase 7
, apoptotic protease Mch-3
, cysteine protease LICE2
, ICE-like apoptotic protease 3
, apoptotic protease MCH-3
, caspase 7, apoptosis-related cysteine protease
, Apoptotic protease Mch-3
, SREBP cleavage activity 2