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Browse our CD11b Proteins (ITGAM)

Full name:
Integrin alpha M Proteins (ITGAM)
On are 21 Integrin alpha M (ITGAM) Proteins from 7 different suppliers available. Additionally we are shipping CD11b Antibodies (1069) and CD11b Kits (17) and many more products for this protein. A total of 1111 CD11b products are currently listed.
C3bi, CD11B, CD11b/CD18, CR3, CR3A, F730045J24Rik, Ly-40, MAC-1, Mac-1a, MAC1, MAC1A, MO1A, SLEB6
list all proteins Gene Name GeneID UniProt
ITGAM 16409  
ITGAM 25021  
ITGAM 3684 P11215

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CD11b Proteins (ITGAM) by Origin

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More Proteins for CD11b Interaction Partners

Mouse (Murine) Integrin alpha M (ITGAM) interaction partners

  1. Intestinal CD103 (show ITGAE Proteins)(+)CD11b(-) dendritic cells restrain colitis via IFN-gamma-induced (show SAMHD1 Proteins) anti-inflammatory response in epithelial cells.

  2. CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs.

  3. this study demonstrates the feasibility of anti-CD11b antibody mediated noninvasive SPECT/CT imaging of inflammatory leukocytes in murine atherosclerotic plaques

  4. Antigen-specific cytotoxic T lymphocytes target airway CD103 (show ITGAE Proteins)+ and CD11b+ dendritic cells to suppress allergic inflammation.

  5. Data show that intestinal tumor development is accompanied by infiltrating CD11b+ antigen myeloid cells.

  6. Data show that in the absence of CD11b antigen, there is an increase in adipose tissue macrophages (ATMs) in situ proliferation and an enhancement of alternatively polarized phenotypes.

  7. Identify an antiinflammatory population of CD11b(+) mononuclear cells that are protective in hyperoxia-induced neonatal lung injury in mice.

  8. There is an increased intracellular TNF (show TNF Proteins) production and FasL (show FASL Proteins) expression in CD11b+ Kupffer cells/Mphi during liver regeneration after partial hepatectomy.

  9. Gr-1 (show GSR Proteins)(+) CD11b(+) cells found in bone marrow from immunosuppressed mice acquire their suppressive activity in the same niche where they are generated, and migrate to lymph nodes to exert their inhibitory role.

  10. CD11b on B-1 cells senses infection-induced innate signals and facilitates their rapid sequester into secondary lymphoid tissues, thereby regulating the accumulation of polyreactive IgM producers at sites of infection.

Human Integrin alpha M (ITGAM) interaction partners

  1. Ingestion of amino acid supplement did not influence CD11b expression.

  2. This metaanalysis indicates that polymorphisms in the pathways of immune complex clearance, such as the FcgammaRIIIa, FcgammaRIIIb, and ITGAM genotypes, are potential susceptibility genes for neuropsychiatric systemic lupus erythematosus.

  3. Monocyte-platelet aggregates and CD11b expression on monocytes and granulocytes are increased in atrial fibrillation patients with proven thrombus formation. They seem to be appropriate biomarkers for stratification of thromboembolic risk in patients with AF.

  4. CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs.

  5. There is direct interaction between C3(H2O) and CD11b. Contact-activated C3(H2O) is a novel ligand for CD11b/CD18 that mediates platelet-PMN (show TBCE Proteins) complex formation and the binding of platelet-derived microparticles to PMNs.

  6. Data show that secreted aspartic protease 2 (Sap2) of Candida albicans inactivates human macrophage complement factor H (factor H (show CFH Proteins)), factor H (show CFH Proteins)-receptors CD11b/CD18 and CD11c (show ITGAX Proteins)/CD18 (show ITGB2 Proteins).

  7. we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 Proteins), FOLR2 (show FOLR2 Proteins), CD68 (show CD68 Proteins) and CD11b markers

  8. While total surface expression of CD11b and L-selectin (show SELL Proteins) on neutrophils was largely unaffected

  9. CD11b expression level might be considered a prognostic biomarker for Acute Myeloid Leukemia (show BCL11A Proteins) patients. [meta-analysis]

  10. analysis of neutrophil and monocyte expression of toll-like receptor 4 (show TLR4 Proteins), CD11b and reactive oxygen intermediates, and correlation with neuroimaging outcomes in preterm infants

Cow (Bovine) Integrin alpha M (ITGAM) interaction partners

  1. These data describe the presence of specific pattern recognition receptor transcripts in the mRNA isolated from bovine neutrophil and show a CD11b-/Ca(2 (show CA2 Proteins)+) dependent ROS (show ROS1 Proteins) production

  2. The molecular cloning and characterization of CD11b from cattle and its similarities to other species are presented.

Pig (Porcine) Integrin alpha M (ITGAM) interaction partners

CD11b (ITGAM) Protein Profile

Protein Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CD11b (ITGAM)

  • integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM)
  • integrin alpha M (Itgam)
  • integrin, alpha M (Itgam)
  • integrin, alpha M (complement component 3 receptor 3 subunit) (Itgam)
  • C3bi protein
  • CD11B protein
  • CD11b/CD18 protein
  • CR3 protein
  • CR3A protein
  • F730045J24Rik protein
  • Ly-40 protein
  • MAC-1 protein
  • Mac-1a protein
  • MAC1 protein
  • MAC1A protein
  • MO1A protein
  • SLEB6 protein

Protein level used designations for Integrin alpha M Proteins (ITGAM)

MAC-1 alpha subunit , integrin alpha M , integrin alpha-M , CD11 antigen-like family member B , CD11B (p170) , CR-3 alpha chain , Mac-1 alpha , cell surface glycoprotein MAC-1 alpha subunit , cell surface glycoprotein MAC-1 subunit alpha , complement component receptor 3 alpha-a , complement receptor type 3 , leukocyte adhesion receptor MO1 , macrophage antigen alpha , antigen CD11b (p170) , macrophage antigen alpha polypeptide , neutrophil adherence receptor alpha-M subunit , leukocyte integrin alpha-M chain , complement receptor 3 , leukocyte integrin alpha M

454069 Pan troglodytes
16409 Mus musculus
25021 Rattus norvegicus
3684 Homo sapiens
407124 Bos taurus
443217 Ovis aries
397459 Sus scrofa
489928 Canis lupus familiaris
100351865 Oryctolagus cuniculus
100135561 Cavia porcellus
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