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Browse our CD11b Proteins (ITGAM)

Full name:
Integrin alpha M Proteins (ITGAM)
On are 22 Integrin alpha M (ITGAM) Proteins from 8 different suppliers available. Additionally we are shipping CD11b Antibodies (962) and CD11b Kits (14) and many more products for this protein. A total of 1003 CD11b products are currently listed.
C3bi, CD11B, CD11b/CD18, CR3, CR3A, F730045J24Rik, Ly-40, MAC-1, Mac-1a, MAC1, MAC1A, MO1A, SLEB6
list all proteins Gene Name GeneID UniProt
ITGAM 16409  
ITGAM 25021  
ITGAM 3684 P11215

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CD11b Proteins (ITGAM) by Origin

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More Proteins for CD11b Interaction Partners

Mouse (Murine) Integrin alpha M (ITGAM) interaction partners

  1. Data show that intestinal tumor development is accompanied by infiltrating CD11b+ antigen myeloid cells.

  2. Data show that in the absence of CD11b antigen, there is an increase in adipose tissue macrophages (ATMs) in situ proliferation and an enhancement of alternatively polarized phenotypes.

  3. Identify an antiinflammatory population of CD11b(+) mononuclear cells that are protective in hyperoxia-induced neonatal lung injury in mice.

  4. There is an increased intracellular TNF (show TNF Proteins) production and FasL (show FASL Proteins) expression in CD11b+ Kupffer cells/Mphi during liver regeneration after partial hepatectomy.

  5. Gr-1 (show GSR Proteins)(+) CD11b(+) cells found in bone marrow from immunosuppressed mice acquire their suppressive activity in the same niche where they are generated, and migrate to lymph nodes to exert their inhibitory role.

  6. CD11b on B-1 cells senses infection-induced innate signals and facilitates their rapid sequester into secondary lymphoid tissues, thereby regulating the accumulation of polyreactive IgM producers at sites of infection.

  7. CD11b and CXCR4 (show CXCR4 Proteins) but not CCR7 (show CCR7 Proteins) have roles in neutrophil migration modulating lymph node lymphocyte proliferation in bacterial infections

  8. The findings implicate complement receptor 3 and C3, but not Fcalpha/muR, in IgM-mediated phagocytosis of S. aureus by microglia.

  9. CD11b on mononuclear cells is instrumental in generating an anti-inflammatory response in the inflamed kidney.

  10. Interleukin-12-producing CD103 (show ITGAE Proteins)+ CD11b- CD8 (show CD8A Proteins)+ dendritic cells are responsible for eliciting gut (show GUSB Proteins) intraepithelial lymphocyte response against Encephalitozoon cuniculi.

Human Integrin alpha M (ITGAM) interaction partners

  1. There is direct interaction between C3(H2O) and CD11b. Contact-activated C3(H2O) is a novel ligand for CD11b/CD18 that mediates platelet-PMN (show TBCE Proteins) complex formation and the binding of platelet-derived microparticles to PMNs.

  2. Data show that secreted aspartic protease 2 (Sap2) of Candida albicans inactivates human macrophage complement factor H (factor H (show CFH Proteins)), factor H (show CFH Proteins)-receptors CD11b/CD18 and CD11c (show ITGAX Proteins)/CD18 (show ITGB2 Proteins).

  3. we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 Proteins), FOLR2 (show FOLR2 Proteins), CD68 (show CD68 Proteins) and CD11b markers

  4. While total surface expression of CD11b and L-selectin (show SELL Proteins) on neutrophils was largely unaffected

  5. CD11b expression level might be considered a prognostic biomarker for Acute Myeloid Leukemia (show BCL11A Proteins) patients. [meta-analysis]

  6. analysis of neutrophil and monocyte expression of toll-like receptor 4 (show TLR4 Proteins), CD11b and reactive oxygen intermediates, and correlation with neuroimaging outcomes in preterm infants

  7. the results identify dynorphins A and B as novel ligands for Mac-1.

  8. A novel expanding CD11b+ conventional dendritic cell subpopulation dominates the infiltrating renal inflammatory milieu, localizing to the glomeruli, in lupus nephritis.

  9. Modification of Levels of Adhesion Molecule (show NCAM1 Proteins) Expression of Human Innate Immune Cells by Glycopolymers of Marine Bacteria

  10. study supports the crucial role of GABP in myeloid cell differentiation and identified ITGAM/CD11b as a novel GABP target gene

Cow (Bovine) Integrin alpha M (ITGAM) interaction partners

  1. These data describe the presence of specific pattern recognition receptor transcripts in the mRNA isolated from bovine neutrophil and show a CD11b-/Ca(2 (show CA2 Proteins)+) dependent ROS (show ROS1 Proteins) production

  2. The molecular cloning and characterization of CD11b from cattle and its similarities to other species are presented.

Pig (Porcine) Integrin alpha M (ITGAM) interaction partners

CD11b (ITGAM) Protein Profile

Protein Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CD11b (ITGAM)

  • integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM)
  • integrin alpha M (Itgam)
  • integrin, alpha M (Itgam)
  • integrin, alpha M (complement component 3 receptor 3 subunit) (Itgam)
  • C3bi protein
  • CD11B protein
  • CD11b/CD18 protein
  • CR3 protein
  • CR3A protein
  • F730045J24Rik protein
  • Ly-40 protein
  • MAC-1 protein
  • Mac-1a protein
  • MAC1 protein
  • MAC1A protein
  • MO1A protein
  • SLEB6 protein

Protein level used designations for Integrin alpha M Proteins (ITGAM)

MAC-1 alpha subunit , integrin alpha M , integrin alpha-M , CD11 antigen-like family member B , CD11B (p170) , CR-3 alpha chain , Mac-1 alpha , cell surface glycoprotein MAC-1 alpha subunit , cell surface glycoprotein MAC-1 subunit alpha , complement component receptor 3 alpha-a , complement receptor type 3 , leukocyte adhesion receptor MO1 , macrophage antigen alpha , antigen CD11b (p170) , macrophage antigen alpha polypeptide , neutrophil adherence receptor alpha-M subunit , leukocyte integrin alpha-M chain , complement receptor 3 , leukocyte integrin alpha M

454069 Pan troglodytes
16409 Mus musculus
25021 Rattus norvegicus
3684 Homo sapiens
407124 Bos taurus
443217 Ovis aries
397459 Sus scrofa
489928 Canis lupus familiaris
100351865 Oryctolagus cuniculus
100135561 Cavia porcellus
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