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Human Clusterin ELISA Kit for Sandwich ELISA - ABIN414571
Yu, Chen, Wang, Zhou, Luo, Xu, Shen, Yin, Tao, Xiao, Xiao, Lü, Wang: Time-dependent decrease of clusterin as a potential cerebrospinal fluid biomarker for drug-resistant epilepsy. in Journal of molecular neuroscience : MN 2014
Show all 4 Pubmed References
Mouse (Murine) Clusterin ELISA Kit for Sandwich ELISA - ABIN415738
Kwon, Ju, Heo, Kim, Kim, Won, Kim, Bae, Park, Min, Lee, Park: Deficiency of clusterin exacerbates high-fat diet-induced insulin resistance in male mice. in Endocrinology 2014
Human Clusterin ELISA Kit for Sandwich ELISA - ABIN1979436
Oztas, Ozler, Ersoy, Iskender, Sucak, Ergin, Uygur, Danisman: Increased levels of serum clusterin is associated with intrauterine growth restriction and adverse pregnancy outcomes in preeclampsia. in Journal of perinatal medicine 2016
Human Clusterin ELISA Kit for Sandwich ELISA - ABIN366947
Tzounakas, Georgatzakou, Kriebardis, Papageorgiou, Stamoulis, Foudoulaki-Paparizos, Antonelou, Papassideri: Uric acid variation among regular blood donors is indicative of red blood cell susceptibility to storage lesion markers: A new hypothesis tested. in Transfusion 2015
Zebrafish clusterin is expressed in the notochord and nervous system during development. Clusterin has also role in neuronal cell death and thus, more generally, in neurodegeneration.
Data show that inhibition or targeted knockdown of Notch (show NOTCH1 ELISA Kits) signaling significantly increased clusterin mRNA expression in choroid plexus.
FRET and co-IP assays demonstrated that Clu interacted with beta-amyloid peptide (show APP ELISA Kits), a pathological protein of AD, which suggested a potential effect of SelR (show SEPX1 ELISA Kits) and Abeta (show APP ELISA Kits) with the aid of Clu. The interaction between SelR (show SEPX1 ELISA Kits) and Clu provides a novel avenue for further study on the mechanism of SelR (show SEPX1 ELISA Kits) in AD prevention.
The findings of this study provided further evidence for the CLU risk variant as a candidate gene for Alzheimer disease and may serve as a pre-clinical neuroimaging phenotype of late-onset Alzheimer disease.
Study demonstrate high concentrations of clusterin (CLU) in mucus samples and significantly reduced CLU levels in cases with endometriosis receiving contraception compared to cases with endometriosis without contraception.
Risk-reducing clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in older adults without dementia.
Addition of the minor allele for rs670139 (MS4A4E), rs9331896 (CLU), and rs12155159 (NME8 (show TXNDC3 ELISA Kits)) was nominally associated with change on the DWRT, DSST, and WFT, respectively, in whites. For rs670139 and rs9331896 the association was only significant in individuals bearing at least one APOE (show APOE ELISA Kits) 4 allele in stratified analyses.
CLU expression is related to the cellular type and inversely correlated with the presence of lymph node metastases in medullary thyroid carcinoma.
Melittin is capable of suppressing tumor growth and promoting gemcitabine sensitivity in pancreatic ductal adenocarcinomas by downregulating cholesterol pathway gene CLU.
Data show that ELOVL7 (show ELOVL7 ELISA Kits), SOCS3 (show SOCS3 ELISA Kits), ACSL4 (show ACSL4 ELISA Kits) and CLU were upregulated while PRKAR1A (show PRKAR1A ELISA Kits) and ABCG1 (show ABCG1 ELISA Kits) were downregulated in the phlegm-dampness group.
Both CLU and PLXNA4 (show PLXNA4 ELISA Kits) have been genetically associated with Alzheimer disease (AD) risk and our data thus provide a direct relationship between two AD risk genes. Our data suggest that increasing the levels of PLXNA4 (show PLXNA4 ELISA Kits) or targeting CLU-PLXNA4 (show PLXNA4 ELISA Kits) interactions may have therapeutic value in AD.
Although further studies are required to determine how clusterin suppresses non-specific cellular uptake in phagocytes, our data suggest that clusterin plays a key role in the stealth effect of not only pegylated nanoparticles but also non-pegylated nanoparticles.
clusterin-induced TNF-alpha (show TNF ELISA Kits) and MMP-9 (show MMP9 ELISA Kits) up-regulation is most likely mediated via TLR4 (show TLR4 ELISA Kits) recruitment into lipid rafts; clusterin has a role as an endogenous regulator for TLR4 (show TLR4 ELISA Kits) signaling
susceptibility to experimental pancreatitis is determined by strain and model differences with Clusterin and Pycr1 (show PYCR1 ELISA Kits) alterations
the antioxidant property of clusterin is suggested to regulate the expression of CCL20 (show CCL20 ELISA Kits) in bronchial epithelial cells and the subsequent recruitment of inflammatory dendritic cells in the airway.
these data suggest that activation of prosurvival autophagy by hypoxia in kidney cells requires CLU expression and may be a key cytoprotective mechanism of CLU in the protection of the kidney from hypoxia/ischemia-mediated injury.
Taken together, our results suggest that an NCE-box within the clusterin promoter is necessary for insulin (show INS ELISA Kits)-stimulated hepatic expression of clusterin via SREBP-1c (show SREBF1 ELISA Kits).
Overexpression of clusterin in proximal tubular epithelial cells decreased the levels of Ang II (show AGT ELISA Kits)-stimulated fibrotic markers and AT1R (show AGTRAP ELISA Kits).
Clusterin facilitates stress-induced lipidation of LC3 (show MAP1LC3A ELISA Kits) and autophagosome biogenesis to enhance cancer cell survival.
Results suggest that regulation of clusterin expression by the lymphotoxin beta (show LTB ELISA Kits) signaling pathway and its protein dynamics during immune response suggest a specific role of in the immune system.
we have identified hypothalamic clusterin as a novel anorexigenic molecule that can potentiate central leptin (show LEP ELISA Kits) activity.
Data demonstrate that the resistance of neonatal porcine Sertoli cells to human xenoantibody and complement-mediated lysis is associated with low expression of xenoantigen alpha-Gal and high production of the complement inhibitors clusterin and CD59 (show CD59 ELISA Kits).
These results show that clusterin expression in porcine species is found in an own, as yet unidentified cell type during postnatal developmental stages.
Porcine spermatozoa may delivery CLU, PRM1 (show PRM1 ELISA Kits) and PRM2 (show PRM2 ELISA Kits) mRNAs to the oocyte, which may contribute to zygotic and early embryonic development.
The expression of CLU gene was significantly higher among motility-impaired crossbred bull semen compared to the good quality one.
Clusterin haplotype AA may be a genetic marker on mastitis and other performance for Chinese Holstein cows.
The secretion of the potential zonal marker clusterin by zonal articular chondrocytes in osteoarthritic and healthy articular cartilage, was characterized.
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
, clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)
, aging-associated protein 4
, apolipoprotein J
, complement cytolysis inhibitor
, complement lysis inhibitor
, complement-associated protein SP-40,40
, ku70-binding protein 1
, sulfated glycoprotein 2
, testosterone-repressed prostate message 2
, dimeric acid glycoprotein
, testosterone repressed prostate message 2
, testosterone-repressed prostate message
, testostrone-repressed prostate message 2
, Apolipoprotein J
, testosterone repressed prostate message
, testosterone repressed prostate message-2
, glycoprotein 80
, apolipoprotein J/clusterin
, glycoprotein III
, apolipoprotein J)
, Sulfated glycoprotein 2