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Browse our Clusterin Proteins (CLU)

Full name:
Clusterin Proteins (CLU)
On are 69 Clusterin (CLU) Proteins from 14 different suppliers available. Additionally we are shipping Clusterin Antibodies (399) and Clusterin Kits (118) and many more products for this protein. A total of 600 Clusterin products are currently listed.
40, AI893575, APO-J, ApoJ, Cli, CLU, CLU1, CLU2, D14Ucla3, DAG, GP80, gpIII, KUB1, LOC100136120, MGC53055, MGC89163, NA1/NA2, RATTRPM2B, Sgp-2, Sgp2, SP-40, SP40, Sugp-2, TRPM-2, Trpm2, TRPM2B, Trpmb, xclu, zgc:73352
list all proteins Gene Name GeneID UniProt
CLU 1191 P10909
CLU 24854 P05371
CLU 12759 Q06890

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Clusterin Proteins (CLU) by Origin

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Top referenced Clusterin Proteins

  1. Human Clusterin Protein expressed in HEK-293 Cells - ABIN2180885 : Jones, Jomary: Clusterin. in The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 6 references for ABIN2180885

  2. Human Clusterin Protein expressed in Human Cells - ABIN2004195 : Silkensen, Schwochau, Rosenberg: The role of clusterin in tissue injury. in Biochemistry and cell biology = Biochimie et biologie cellulaire 1995 (PubMed)
    Show all 2 references for ABIN2004195

  3. Mouse (Murine) Clusterin Protein expressed in Human Cells - ABIN2007876 : Djeu, Wei: Clusterin and chemoresistance. in Advances in cancer research 2009 (PubMed)
    Show all 2 references for ABIN2007876

  4. Human Clusterin Protein expressed in Human - ABIN1344084 : Gil, Youn, Byun, Huang, Namkoong, Jang, Lee, Jo, Kang, Kim, Shin, Pietrzik, Lee, Kim, Kim: Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway. in Nature communications 2013 (PubMed)
    Show all 2 references for ABIN1344084

  5. Human Clusterin Protein expressed in Escherichia coli (E. coli) - ABIN1344142 : Shim, Kang, Jeon, Park, Lee, Lee, Park, Lee, Schedin, Min: Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF-?B pathways in monocytes/macrophages. in Journal of leukocyte biology 2011 (PubMed)

More Proteins for Clusterin Interaction Partners

Zebrafish Clusterin (CLU) interaction partners

  1. Zebrafish clusterin is expressed in the notochord and nervous system during development. Clusterin has also role in neuronal cell death and thus, more generally, in neurodegeneration.

  2. Data show that inhibition or targeted knockdown of Notch (show NOTCH1 Proteins) signaling significantly increased clusterin mRNA expression in choroid plexus.

Human Clusterin (CLU) interaction partners

  1. Study identified significant association of the CLU rs9331888 polymorphism with Alzheimer's disease susceptibility in Caucasian population but not in East Asian population (Meta-analysis).

  2. Our results suggest clusterin plays a role in modulating the inflammatory response of acute and chronic traumatic brain injury and that it is a useful marker for TBI (show TBPL1 Proteins), particularly in cases with short survival times. Its prominent accumulation in astrocytes, alongside a mounting inflammatory response and activation of microglial cells supports a potential role in the neurodegenerative changes that occur as a result of TBI (show TBPL1 Proteins).

  3. Seminal clusterin was a significant predictor of sperm retrieval in infertile men.

  4. abnormal sCLU expression associated with tumor progression could be a potential diagnostic and prognostic biomarker for HCC (show FAM126A Proteins).

  5. CLU protein is involved with late onset Alzheimer's disease. [review]

  6. When clusterin is expressed in endometrial tumors, it is associated with lower stage.

  7. increased levels of clusterin are associated with IUGR and probably predictive for adverse pregnancy outcomes in preeclampsia

  8. cross-domain interactions showed that personality trait effects on declarative memory were moderated by APOE (show APOE Proteins) and CLU allelic risk.

  9. we identified sCLU as a novel miR (show MLXIP Proteins)-378 target, and we showed that targeting sCLU via miR (show MLXIP Proteins)-378 may help disable the chemoresistance against cisplatin in lung adenocarcinoma cells.

  10. The genotype frequency of CLU (rs11136000, rs1532278, rs7012010, rs9331888) in a cohort of patients with CAA (show TSHZ1 Proteins)-associated intracerebral hemorrhage was compared with hypertension-associated ICH (show COL4a2 Proteins), Alzheimer disease, and controls. The CLU genotypes were not different among groups. ApoJ/clusterin appears to be a chaperone related to distinctive lesions in CAA (show TSHZ1 Proteins) brains.

Mouse (Murine) Clusterin (CLU) interaction partners

  1. the antioxidant property of clusterin is suggested to regulate the expression of CCL20 (show CCL20 Proteins) in bronchial epithelial cells and the subsequent recruitment of inflammatory dendritic cells in the airway.

  2. these data suggest that activation of prosurvival autophagy by hypoxia in kidney cells requires CLU expression and may be a key cytoprotective mechanism of CLU in the protection of the kidney from hypoxia/ischemia-mediated injury.

  3. Taken together, our results suggest that an NCE-box within the clusterin promoter is necessary for insulin (show INS Proteins)-stimulated hepatic expression of clusterin via SREBP-1c (show SREBF1 Proteins).

  4. Overexpression of clusterin in proximal tubular epithelial cells decreased the levels of Ang II (show AGT Proteins)-stimulated fibrotic markers and AT1R (show AGTRAP Proteins).

  5. Clusterin facilitates stress-induced lipidation of LC3 (show MAP1LC3A Proteins) and autophagosome biogenesis to enhance cancer cell survival.

  6. Results suggest that regulation of clusterin expression by the lymphotoxin beta (show LTB Proteins) signaling pathway and its protein dynamics during immune response suggest a specific role of in the immune system.

  7. we have identified hypothalamic clusterin as a novel anorexigenic molecule that can potentiate central leptin (show LEP Proteins) activity.

  8. This study provides the first evidence that sCLU reduces OC formation by inhibiting the actions of M-CSF (show CSF1R Proteins), thereby suggesting its protective role in bone erosion.

  9. results suggest that clusterin plays a protective role against high-fat diet-induced insulin (show INS Proteins) resistance through the suppression of oxidative stress and inflammation.

  10. These results showed that clusterin expression is modulated dynamically during development and by sensory activity.

Pig (Porcine) Clusterin (CLU) interaction partners

  1. Data demonstrate that the resistance of neonatal porcine Sertoli cells to human xenoantibody and complement-mediated lysis is associated with low expression of xenoantigen alpha-Gal and high production of the complement inhibitors clusterin and CD59 (show CD59 Proteins).

  2. These results show that clusterin expression in porcine species is found in an own, as yet unidentified cell type during postnatal developmental stages.

  3. Porcine spermatozoa may delivery CLU, PRM1 (show PRM1 Proteins) and PRM2 (show PRM2 Proteins) mRNAs to the oocyte, which may contribute to zygotic and early embryonic development.

Cow (Bovine) Clusterin (CLU) interaction partners

  1. The expression of CLU gene was significantly higher among motility-impaired crossbred bull semen compared to the good quality one.

  2. Clusterin haplotype AA may be a genetic marker on mastitis and other performance for Chinese Holstein cows.

Horse (Equine) Clusterin (CLU) interaction partners

  1. The secretion of the potential zonal marker clusterin by zonal articular chondrocytes in osteoarthritic and healthy articular cartilage, was characterized.

Clusterin (CLU) Protein Profile

Protein Summary

The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.

Alternative names and synonyms associated with Clusterin (CLU)

  • clusterin-1 (LOC100136120)
  • clusterin (clu)
  • clusterin (CLU)
  • Clusterin (clus)
  • clusterin (Clu)
  • 40 protein
  • AI893575 protein
  • APO-J protein
  • ApoJ protein
  • Cli protein
  • CLU protein
  • CLU1 protein
  • CLU2 protein
  • D14Ucla3 protein
  • DAG protein
  • GP80 protein
  • gpIII protein
  • KUB1 protein
  • LOC100136120 protein
  • MGC53055 protein
  • MGC89163 protein
  • NA1/NA2 protein
  • RATTRPM2B protein
  • Sgp-2 protein
  • Sgp2 protein
  • SP-40 protein
  • SP40 protein
  • Sugp-2 protein
  • TRPM-2 protein
  • Trpm2 protein
  • TRPM2B protein
  • Trpmb protein
  • xclu protein
  • zgc:73352 protein

Protein level used designations for Clusterin Proteins (CLU)

clusterin-1 , clusterin , clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) , Clusterin , aging-associated protein 4 , apolipoprotein J , complement cytolysis inhibitor , complement lysis inhibitor , complement-associated protein SP-40,40 , ku70-binding protein 1 , sulfated glycoprotein 2 , testosterone-repressed prostate message 2 , dimeric acid glycoprotein , testosterone repressed prostate message 2 , testosterone-repressed prostate message , testostrone-repressed prostate message 2 , Apolipoprotein J , apo-J , clustrin , testosterone repressed prostate message , testosterone repressed prostate message-2 , glycoprotein 80 , apolipoprotein J/clusterin , CLI , CP40 , glycoprotein III , apolipoprotein J) , Sulfated glycoprotein 2

100136120 Oncorhynchus mykiss
380468 Xenopus laevis
393775 Danio rerio
448332 Xenopus (Silurana) tropicalis
464075 Pan troglodytes
677866 Macaca mulatta
100380352 Salmo salar
1191 Homo sapiens
24854 Rattus norvegicus
12759 Mus musculus
442971 Canis lupus familiaris
100008713 Oryctolagus cuniculus
100734772 Cavia porcellus
397025 Sus scrofa
280750 Bos taurus
100034172 Equus caballus
101113728 Ovis aries
395722 Gallus gallus
101836902 Mesocricetus auratus
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