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Browse our anti-FADD (FADD) Antibodies

Full name:
anti-Fas (TNFRSF6)-Associated Via Death Domain Antibodies (FADD)
On are 267 Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies from 27 different suppliers available. Additionally we are shipping FADD Proteins (14) and FADD Kits (13) and many more products for this protein. A total of 319 FADD products are currently listed.
Mort1, Mort1/FADD, TNFRSF6
list all antibodies Gene Name GeneID UniProt
FADD 8772 Q13158
FADD 14082 Q61160
FADD 266610  

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Most Popular Reactivities for anti-FADD (FADD) Antibodies

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anti-Human FADD Antibodies:

anti-Mouse (Murine) FADD Antibodies:

anti-Rat (Rattus) FADD Antibodies:

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Top referenced anti-FADD Antibodies

  1. Human Monoclonal FADD Primary Antibody for WB - ABIN395764 : Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: Dengue hemorrhagic fever is associated with polymorphisms in JAK1. in European journal of human genetics : EJHG 2010 (PubMed)
    Show all 5 references for ABIN395764

  2. Human Monoclonal FADD Primary Antibody for IF, IP - ABIN967944 : Chang, Xing, Pan, Algeciras-Schimnich, Barnhart, Yaish-Ohad, Peter, Yang: c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. in The EMBO journal 2002 (PubMed)
    Show all 5 references for ABIN967944

  3. Human Polyclonal FADD Primary Antibody for EIA, IHC (p) - ABIN358126 : Hsu, Shu, Pan, Goeddel: TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. in Cell 1996 (PubMed)
    Show all 3 references for ABIN358126

  4. Human Monoclonal FADD Primary Antibody for EIA, IHC (p) - ABIN317514 : Bannerman, Tupper, Kelly, Winn, Harlan: The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta. in The Journal of clinical investigation 2002 (PubMed)
    Show all 3 references for ABIN317514

  5. Human Polyclonal FADD Primary Antibody for IP, WB - ABIN222894 : Chen, Texada, Duggan, Liang, Reden, Kooragayala, Langford: Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells. in The Journal of biological chemistry 2005 (PubMed)
    Show all 3 references for ABIN222894

  6. Mouse (Murine) Polyclonal FADD Primary Antibody for WB - ABIN389559 : Zhang, Winoto: A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis. in Molecular and cellular biology 1996 (PubMed)
    Show all 2 references for ABIN389559

  7. Human Monoclonal FADD Primary Antibody for IP, WB - ABIN967524 : Cleveland, Ihle: Contenders in FasL/TNF death signaling. in Cell 1995 (PubMed)
    Show all 2 references for ABIN967524

  8. Human Polyclonal FADD Primary Antibody for WB - ABIN669471 : Soni, Adebiyi: Early septic insult in neonatal pigs increases serum and urinary soluble Fas ligand and decreases kidney function without inducing significant renal apoptosis. in Renal failure 2016 (PubMed)

  9. Human Polyclonal FADD Primary Antibody for IF, IHC - ABIN1534444 : Chinnaiyan, ORourke, Tewari, Dixit: FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. in Cell 1995 (PubMed)

  10. Human Polyclonal FADD Primary Antibody for IHC, WB - ABIN2792110 : Thomas, Henson, Reed, Salsbury, Thorburn: Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against FADD Interaction Partners

Human Fas (TNFRSF6)-Associated Via Death Domain (FADD) interaction partners

  1. Data indicate that FADD mediated apoptotic cell death was directed by ubiquitination of cFLIPL and inhibition of NF-kappaB (show NFKB1 Antibodies) activation.

  2. Structural analysis for the roles of DR5 death domain mutations on oligomerization of DR5 death domain-FADD complex in the death-inducing signaling complex formation has been presented.

  3. A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

  4. TCGA analysis showed that ANO1 and FADD, located at 11q13, were co-expressed at transcript level and significantly associated with overall and disease-free survival

  5. Data (including data obtained in transgenic mice) suggest FADD is key in genesis of neural tube defects in pups of diabetic mice; unfolded protein response/endoplasmic reticulum stress was prevented by over-expression of human dominant negative FADD.

  6. multifaceted kinase, CK2, phosphorylates FADD and is involved in its sub-cellular localization.

  7. domains of calmodulin (show CALM1 Antibodies) mediate FADD and TRADD (show TRADD Antibodies) interaction

  8. The gene expression analysis showed statistically significant difference between cases and healthy controls for both FADD (p<0.02) and FAS (show FAS Antibodies) (p<0.007) genes

  9. Observed upregulation of cortical p-194 FADD and p-FADD/FADD ratio (higher pro-survival index) in major depression; could play a major role to counteract the known activation of the intrinsic (mitochondrial) apoptotic pathway in the brain

  10. FADD death effector domain and c-FLIP (show CFLAR Antibodies) death effector domain structures, the binding activity of FADD DED (show AATF Antibodies) to the c-FLIP (show CFLAR Antibodies) death effector domains, and the protein-protein interactions involving the regulation of both apoptosis and necrosis.

Mouse (Murine) Fas (TNFRSF6)-Associated Via Death Domain (FADD) interaction partners

  1. A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

  2. Deletion of FADD in macrophages and granulocytes results in RIP3 (show MPRIP Antibodies)- and MyD88 (show MYD88 Antibodies)-dependent systemic inflammation.

  3. A constitutively phosphoryl-mimicking mutation of Fas (show FAS Antibodies)-associated death domain (FADD-D) enhances Notch-1 (show NOTCH1 Antibodies) signaling and compromises Wnt (show WNT2 Antibodies) signaling in both cultured myoblasts and regenerating muscles.

  4. Beta amyloid-induced upregulation of death receptor 6 (show TNFRSF21 Antibodies) accelerates the toxic effect of N-terminal fragment of amyloid precursor protein (show APP Antibodies)

  5. Phosphorylation of FADD by the kinase CK1alpha (show CSNK1A1 Antibodies) promotes KRASG12D-induced lung cancer.

  6. This study evaluated the role of FADD in pancreatic islets and insulin (show INS Antibodies) secretion.

  7. depletion of alphaNAC in multiple types of cancer cells induce typical apoptotic cell death. This anti-apoptotic function is mediated by the FADD/c-Jun N-terminal kinase pathway.

  8. These data suggest that as a death receptor, FADD is also required for cell survival in beta-selection as a regulator of Notch1 (show NOTCH1 Antibodies) expression.

  9. using T-cell specific deletion mice, we observed that FADD deficiency in thymocytes led to increased apoptosis and reduced cell numbers, which may be attributed to the reduction of Glut1 (show SLC2A1 Antibodies) expression and correspondingly decreased glucose uptake

  10. RIPK1 (show RIPK1 Antibodies), FADD, and caspase-8 (show CASP8 Antibodies) are required for YopJ-induced cell death and caspase-1 (show CASP1 Antibodies) activation

Pig (Porcine) Fas (TNFRSF6)-Associated Via Death Domain (FADD) interaction partners

  1. FADD induces apoptosis

Cow (Bovine) Fas (TNFRSF6)-Associated Via Death Domain (FADD) interaction partners

  1. mapping and sequencing of bovine FADD cDNA, and characterization of its expression in endothelial cells

FADD Antigen Profile

Antigen Summary

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

Alternative names and synonyms associated with FADD

  • Fas (TNFRSF6)-associated via death domain (FADD) antibody
  • Fas (TNFRSF6)-associated via death domain (Fadd) antibody
  • Mort1 antibody
  • Mort1/FADD antibody
  • TNFRSF6 antibody

Protein level used designations for FADD

Fas-associating death domain-containing protein , Fas-associating protein with death domain , growth-inhibiting gene 3 protein , mediator of receptor induced toxicity , mediator of receptor-induced toxicity , protein FADD , FAS-associated death domain protein , FAS-associating death domain-containing protein , Fas (TNF receptor superfamily, member 6) , Fas-associated via death domain

8772 Homo sapiens
14082 Mus musculus
266610 Rattus norvegicus
595129 Sus scrofa
493720 Bos taurus
611694 Canis lupus familiaris
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