Browse our Lamin B1 Proteins (LMNB1)

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Lamin B1 Proteins (LMNB1)
On are 7 Lamin B1 (LMNB1) Proteins from 5 different suppliers available. Additionally we are shipping Lamin B1 Antibodies (150) and Lamin B1 Kits (12) and many more products for this protein. A total of 180 Lamin B1 products are currently listed.
ADLD, fc06g01, lamin-b, Lamin-L(I), LMN, LMN2, LMNB, LMNB1, MGC52550, wu:fc06g01
list all proteins Gene Name GeneID UniProt
LMNB1 4001 P20700
LMNB1 16906 P14733
LMNB1 116685 P70615

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Lamin B1 Proteins (LMNB1) by Origin

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Top referenced Lamin B1 Proteins

  1. Human Lamin B1 Protein expressed in HEK-293 Cells - ABIN2724477 : Baghirova, Hughes, Poirier, Kondo, Schulz: Nuclear matrix metalloproteinase-2 in the cardiomyocyte and the ischemic-reperfused heart. in Journal of molecular and cellular cardiology 2016 (PubMed)

More Proteins for Lamin B1 Interaction Partners

Xenopus laevis Lamin B1 (LMNB1) interaction partners

  1. Lamin B counteracts the kinesin Eg5 (show KIF11 Proteins) to restrain spindle pole separation during spindle assembly.

Human Lamin B1 (LMNB1) interaction partners

  1. The primary response of cells to various stresses leading to senescence consists of the down-regulation of LBR (show LBR Proteins) and LB1 (show CKAP2 Proteins) to attain reversal of the chromatin architecture.

  2. Data show that lamins A and B are differently processed in staurosporine and beta-Amyloid peptide (show APP Proteins) fragments Abeta42-treated cells.

  3. The tail domain of lamin B1 is more strongly modulated by divalent cations than lamin A (show LMNA Proteins).

  4. An upstream mutation alters LMNB1 gene expression in autosomal dominant adult-onset demyelinating leukodystrophy.

  5. Deregulation of LMNB1 expression induces modified splicing of several genes, likely driven by raver-2 overexpression, and suggest that an alteration of mRNA processing could be a pathogenic mechanism in adult-onset autosomal dominant leukodystrophy.

  6. Lamin B1 levels are increased in oligodendrocytes, the cell type that produces myelin in the central nervous system.

  7. Nuclear envelope remodelling during human spermiogenesis involves somatic B-type lamins and a spermatid-specific B3 lamin (show LMNA Proteins) isoform.

  8. LMNB1-related autosomal-dominant leukodystrophy is a slowly progressive neurological disease with survival lasting more than two decades after clinical onset.

  9. Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts.

  10. Data indicate that lamin B1 promotes DNA double-strand breaks (DSBs) repair and cell survival.

Mouse (Murine) Lamin B1 (LMNB1) interaction partners

  1. While the distribution patterns of both lamins closely paralleled the respective stages of mitosis, Nup160 (show NUP160 Proteins) localization in metaphase oocytes corresponded to that in mitotic prometaphase rather than metaphase.

  2. Here we report that in primary mouse cortical neurons, LMNB1 overexpression reduces axonal outgrowth, whereas deficiency of endogenous Lmnb1 results in aberrant dendritic development.

  3. Analysis of lamin B1 expression in different regions of the brain in wild-type animals showed that the level of Lmnb1 transcript decreased significantly in an age-dependent manner.

  4. Lamin-B1 is required for organization of lamin-A/C (show LMNA Proteins) and lamin-B2 (show LMNB2 Proteins) in mouse embryonic stem cells and Lamin-B1 is required for organization of lamin-A/C (show LMNA Proteins) and lamin-B2 (show LMNB2 Proteins) in differentiated cells

  5. farnesylation of lamin B1--but not lamin B2 (show LMNB2 Proteins)--is crucial for brain development and for retaining chromatin within the bounds of the nuclear lamina during neuronal migration.

  6. lamin B1 overexpression mediates oligodendrocyte cell-autonomous neuropathology in adult-onset autosomal-dominant leukodystrophy.

  7. We conclude that lamin B1 is a modifier gene of major effect for Neural tube defects resulting from loss of Grhl3 (show GRHL3 Proteins) function

  8. Lamin B1 is lost from primary human and murine cell strains when they are induced to senesce.

  9. Lamin B1 is essential for brain development and is required for the integrity of the nuclear lamina.

  10. Absence of both Lmnb1 and Lmnb2 (show LMNB2 Proteins) in keratinocytes has no effect on cell proliferation or the development of skin and hair.

Lamin B1 (LMNB1) Protein Profile

Protein Summary

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Alternative names and synonyms associated with Lamin B1 (LMNB1)

  • lamin B1 (lmnb1)
  • lamin B1 (LMNB1)
  • lamin B1 (LOC100037680)
  • lamin B1 (Lmnb1)
  • ADLD protein
  • fc06g01 protein
  • lamin-b protein
  • Lamin-L(I) protein
  • LMN protein
  • LMN2 protein
  • LMNB protein
  • LMNB1 protein
  • MGC52550 protein
  • wu:fc06g01 protein

Protein level used designations for Lamin B1 Proteins (LMNB1)

lamin B1 , lamin-B1-like , lamin-B1

379745 Xenopus laevis
394806 Xenopus (Silurana) tropicalis
462035 Pan troglodytes
703575 Macaca mulatta
100395999 Callithrix jacchus
100431365 Pongo abelii
100584344 Nomascus leucogenys
4001 Homo sapiens
474663 Canis lupus familiaris
540643 Bos taurus
100037680 Ovis aries
100346094 Oryctolagus cuniculus
16906 Mus musculus
116685 Rattus norvegicus
195816 Danio rerio
396223 Gallus gallus
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