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Lamin B1 Protein (LMNB1) (AA 387-587) (His tag)

LMNB1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505477
  • Target See all Lamin B1 (LMNB1) Proteins
    Lamin B1 (LMNB1)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 387-587
    Origin
    • 8
    • 4
    • 3
    Rat
    Source
    • 6
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Lamin B1 protein is labelled with His tag.
    Sequence
    Arg387-Met587
    Characteristics
    A DNA sequence encoding the Rat Lamin B1 (P70615-1) (Arg387-Met587) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    >90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product LMNB1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    Lamin B1 (LMNB1)
    Alternative Name
    Lamin B1 (LMNB1 Products)
    Synonyms
    MGC52550 Protein, Lamin-L(I) Protein, lamin-b Protein, lmn Protein, lmn2 Protein, lmnb Protein, LMNB1 Protein, ADLD Protein, LMN Protein, LMN2 Protein, LMNB Protein, fc06g01 Protein, wu:fc06g01 Protein, lamin B1 L homeolog Protein, lamin B1 Protein, lmnb1.L Protein, lmnb1 Protein, LMNB1 Protein, Lmnb1 Protein
    Background

    Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

    Synonym: ADLD,lamin B1,Lamin-B1,LMN,LMN2,LMNB,Lmnb1,LMNB1,MGC111419,OTTHUMP00000159218

    Molecular Weight
    22.1 kDa
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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