Lamin B1 Protein (LMNB1) (AA 387-587) (His tag)
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- Target See all Lamin B1 (LMNB1) Proteins
- Lamin B1 (LMNB1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 387-587
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Lamin B1 protein is labelled with His tag.
- Sequence
- Arg387-Met587
- Characteristics
- A DNA sequence encoding the Rat Lamin B1 (P70615-1) (Arg387-Met587) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product LMNB1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Lamin B1 (LMNB1)
- Alternative Name
- Lamin B1 (LMNB1 Products)
- Synonyms
- MGC52550 Protein, Lamin-L(I) Protein, lamin-b Protein, lmn Protein, lmn2 Protein, lmnb Protein, LMNB1 Protein, ADLD Protein, LMN Protein, LMN2 Protein, LMNB Protein, fc06g01 Protein, wu:fc06g01 Protein, lamin B1 L homeolog Protein, lamin B1 Protein, lmnb1.L Protein, lmnb1 Protein, LMNB1 Protein, Lmnb1 Protein
- Background
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Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Synonym: ADLD,lamin B1,Lamin-B1,LMN,LMN2,LMNB,Lmnb1,LMNB1,MGC111419,OTTHUMP00000159218
- Molecular Weight
- 22.1 kDa
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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