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Browse our TNFSF10 (TNFSF10) ELISA Kits

Full name:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 ELISA Kits (TNFSF10)
On www.antibodies-online.com are 47 Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) ELISA Kits from 19 different suppliers available. Additionally we are shipping TNFSF10 Antibodies (364) and TNFSF10 Proteins (71) and many more products for this protein. A total of 501 TNFSF10 products are currently listed.
Synonyms:
A330042I21Rik, AI448571, APO-2L, APO2L, CD253, Ly81, TL2, Trail, trail1, xtrail1
list all ELISA KIts Gene Name GeneID UniProt
TNFSF10 8743 P50591
TNFSF10 22035 P50592
TNFSF10 246775  

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Top referenced TNFSF10 ELISA Kits

  1. Human TNFSF10 ELISA Kit for Sandwich ELISA - ABIN415276 : Cheng, Liu, Wang, Zhang, Zhao, Zhang, Jiang: Soluble TRAIL Concentration in Serum Is Elevated in People with Hypercholesterolemia. in PLoS ONE 2015 (PubMed)

  2. Mouse (Murine) TNFSF10 ELISA Kit for Sandwich ELISA - ABIN415807 : Tisato, Garrovo, Biffi, Petrera, Voltan, Casciano, Meroni, Agnoletto, Zauli, Secchiero: Intranasal administration of recombinant TRAIL down-regulates CXCL-1/KC in an ovalbumin-induced airway inflammation murine model. in PLoS ONE 2014 (PubMed)

More ELISA Kits for TNFSF10 Interaction Partners

Xenopus laevis Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. xTRAIL1 can cause apoptosis, probably mediated through xDR-Ms, in larval red blood cells, but may not kill adult RBCs, presumably owing to PKC (show PKC ELISA Kits) activation, as part of the mechanism for RBC (show CACNA1C ELISA Kits) switching

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. miR (show MLXIP ELISA Kits)-661 overexpression sensitized tumors to TRAIL or STS (show STS ELISA Kits) induced apoptosis in a xenograft mouse model, and these effects were attenuated by co-expression of CYC1 (show CYC1 ELISA Kits).

  2. sorafenib overcomes TRAIL resistance in renal cell carcinoma by a mechanism that does not rely on Mcl-1 (show MCL1 ELISA Kits) down-regulation but involves ROS (show ROS1 ELISA Kits) accumulation and increased activation of caspase-8 (show CASP8 ELISA Kits)

  3. Review: OPG (show TNFRSF11B ELISA Kits), RANKL (show TNFSF11 ELISA Kits) and TRAIL are involved in vascular calcification.

  4. results indicate that E2 inhibits VSMCs proliferation and migration by downregulation of TRAIL expression via suppression of NF-kappaB (show NFKB1 ELISA Kits) pathway.

  5. TRAIL can enhance RIP1 and c-FLIPL (show CFLAR ELISA Kits) expression in HepG2 cells.

  6. TRAIL might promote hypoxic A549 cell radiosensitivity and induce apoptosis depending on DR5 (show TNFRSF10B ELISA Kits) to caspase-3 (show CASP3 ELISA Kits) pathways.

  7. pro-angiogenic responses of TRAIL, vascular endothelial growth-factor-A (VEGF-A (show VEGFA ELISA Kits)) and fibroblast growth-factor-2 (FGF-2 (show FGF2 ELISA Kits)) either separately (10 ng/mL) or in combination were compared, followed by the assessment of proliferation, migration and tubule formation using human microvascular endothelial-1 (HMEC-1) cells.

  8. Combined triple actions of the TRAIL, the IAPs inhibitor, AT406, and the c-FLIP (show CFLAR ELISA Kits) expression inhibitor, rocaglamide (ART), markedly improve TRAIL-induced apoptotic effects in most solid cancer cell lines through the activation of an extrinsic apoptosis pathway

  9. We demonstrate that PBOX-15 can enhance TRAIL-induced apoptosis by upregulation of DR5 (show TNFRSF10B ELISA Kits), reduction of cellular mitochondrial potential, activation of the caspase (show CASP3 ELISA Kits) cascade and downregulation of PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits), c-FLIP (show CFLAR ELISA Kits), Mcl-1 (show MCL1 ELISA Kits) and IAP (show ALPI ELISA Kits) survival pathways

  10. TRAIL may provide a new strategy for CD133hi CSCs of HCC (show FAM126A ELISA Kits)-targeted therapies.

Pig (Porcine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. Data suggest forkhead box protein O1 (FoxO1 (show FOXO1 ELISA Kits)) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL and Fas ligand FasL (show FASL ELISA Kits) expression during follicular atresia.

  2. The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. Tnfsf10 expression is increased in eosinophilic esophagitis. Tnfsf10(-/-) mice were largely protected from esophageal fibrosis and eosinophilic inflammation.

  2. Diabetes significantly increased OPG (show TNFSF11 ELISA Kits) and the OPG (show TNFSF11 ELISA Kits)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (show TNFSF11 ELISA Kits) and reduced TRAIL expression, thus increasing cardiac OPG (show TNFSF11 ELISA Kits)/TRAIL ratio.

  3. TRAIL can promote angiogenesis following hindlimb ischemia in vivo via NOX4 (show NOX4 ELISA Kits)/eNOS (show NOS3 ELISA Kits)/nitric oxide signaling.

  4. Study reports that loss of the Opg (show TNFSF11 ELISA Kits) gene results in deterioration of abdominal aortic aneurysms (AAA (show AAAS ELISA Kits)), possibly through involvement of TRAIL in smooth muscle actin (SMA (show SMN1 ELISA Kits))-positive cells and myofibroblasts.

  5. PARP1 (show PARP1 ELISA Kits) acts as a prominent upstream regulator of high mobility group box 1 (show HMGB1 ELISA Kits)-mediated autophagy and maintains a homeostatic balance between apoptosis and autophagy, which provides new insight into the mechanism of TNFSF10 resistance

  6. Data suggest that Socs3 (suppressor of cytokine signaling 3 (show SOCS3 ELISA Kits)) plays critical negative role in regulation of Trail expression in endoplasmic reticulum stress in macrophages via Jun N-terminal kinase (show MAPK8 ELISA Kits)/AP-1 (show JUN ELISA Kits) transcription factor signaling.

  7. These findings indicate that acute fasting enhances TRAIL-mediated liver natural killer cell activity against neoplastic cells through upregulation of heat shock protein 70 (show HSP70 ELISA Kits).

  8. These results demonstrated that TRAIL plays a deleterious role in acute kidney injury pathogenesis induced by scald (show RDH11 ELISA Kits) burns

  9. TRAIL-deficiency in ApoE (show APOE ELISA Kits)(-/-) mice exacerbates nephropathy and insulin (show INS ELISA Kits) resistance

  10. Tumor necrosis factor (show TNF ELISA Kits)-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease.

TNFSF10 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TNFSF10

  • tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10) Elisa Kit
  • TNF-related apoptosis inducing ligand-like (TRAIL-LIKE) Elisa Kit
  • tumor necrosis factor (ligand) superfamily, member 10 (tnfsf10) Elisa Kit
  • tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10) Elisa Kit
  • A330042I21Rik Elisa Kit
  • AI448571 Elisa Kit
  • APO-2L Elisa Kit
  • APO2L Elisa Kit
  • CD253 Elisa Kit
  • Ly81 Elisa Kit
  • TL2 Elisa Kit
  • Trail Elisa Kit
  • trail1 Elisa Kit
  • xtrail1 Elisa Kit

Protein level used designations for TNFSF10

tumor necrosis factor ligand superfamily member 10 , TNF-related apoptosis inducing ligand , TNF-related apoptosis inducing ligand-like protein , Tnf-alpha related apoptosis inducing ligand , TNF-related apoptosis-inducing ligand 1 , tumor necrosis factor related apoptosis inducing ligand 1 , Apo-2 ligand , TNF-related apoptosis inducing ligand TRAIL , chemokine tumor necrosis factor ligand superfamily member 10 , tumor necrosis factor (ligand) family, member 10 , tumor necrosis factor apoptosis-inducing ligand splice variant delta , tumor necrosis factor-related apoptosis-inducing ligand , TNF-related apoptosis-inducing ligand , TRAIL/APO2L

GENE ID SPECIES
378894 Gallus gallus
395283 Gallus gallus
100174789 Felis catus
100316914 Xenopus laevis
8743 Homo sapiens
100174780 Canis lupus familiaris
406191 Sus scrofa
22035 Mus musculus
246775 Rattus norvegicus
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