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Browse our anti-XIAP (XIAP) Antibodies

Full name:
anti-X-Linked Inhibitor of Apoptosis Antibodies (XIAP)
On www.antibodies-online.com are 163 X-Linked Inhibitor of Apoptosis (XIAP) Antibodies from 30 different suppliers available. Additionally we are shipping XIAP Kits (17) and XIAP Proteins (10) and many more products for this protein. A total of 206 XIAP products are currently listed.
Synonyms:
1110015C02Rik, Aipa, Api3, Birc4, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, MIHA, mXIAP, riap3, XLP2, xxiap

All available anti-XIAP Antibodies

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Top referenced anti-XIAP Antibodies

  1. Dog (Canine) Monoclonal XIAP Primary Antibody for IF, IP - ABIN968132 : Duckett, Nava, Gedrich, Clem, Van Dongen, Gilfillan, Shiels, Hardwick, Thompson: A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. in The EMBO journal 1996 (PubMed)
    Show all 6 references for ABIN968132

  2. Human Polyclonal XIAP Primary Antibody for EIA, IHC (p) - ABIN501135 : Albaladejo, Alonso, Yus: Synthesis of indolizines and heterocyclic chalcones catalyzed by supported copper nanoparticles. in Chemistry (Weinheim an der Bergstrasse, Germany) 2013 (PubMed)
    Show all 6 references for ABIN501135

  3. Frog Monoclonal XIAP Primary Antibody for IF, IP - ABIN968163 : Deng, Lin, Wu: TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. in Genes & development 2002 (PubMed)
    Show all 5 references for ABIN968163

  4. Human Polyclonal XIAP Primary Antibody for EIA, IHC (p) - ABIN358604 : Srinivasula, Gupta, Datta, Zhang, Hegde, Cheong, Fernandes-Alnemri, Alnemri: Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN358604

  5. Human Polyclonal XIAP Primary Antibody for IF (cc), IF (p) - ABIN674364 : Chen, Bai, Zhong, Xie, Long, Yang, Wu, Jia, Wang: Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. in PLoS ONE 2013 (PubMed)
    Show all 3 references for ABIN674364

  6. Human Polyclonal XIAP Primary Antibody for IHC (p), WB - ABIN390070 : Miranda, Dyer, Grandis, Johnson: Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells. in Leukemia 2003 (PubMed)
    Show all 2 references for ABIN390070

More Antibodies against XIAP Interaction Partners

Human X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. AZD5582 draws Mcl-1 (show MCL1 Antibodies) down-regulation for induction of apoptosis through targeting of cIAP1 (show BIRC2 Antibodies) and XIAP in human pancreatic cancer

  2. Data indicate that Smac/DIABLO (show DIABLO Antibodies) showed an inverse correlation with inhibitor of apoptosis proteins XIAP, cIAP-1 (show BIRC2 Antibodies) and cIAP-2 (show BIRC3 Antibodies).

  3. Tumor expression of XIAP helps to identify prostate cancer patients at risk of progression.

  4. XIAP plays a critical role in the control of cytokine-induced cell death by Sestrin2.

  5. XIAP levels increased significantly during treatment in both normal and tumour tissue in accordance with the degree of radio-chemotherapy resistance of the tissue. Disturbance of the XIAP/Smac (show DIABLO Antibodies) balance may be a driver of radio-chemotherapy resistance.

  6. It was concluded that high expression of HtrA1 (show HTRA1 Antibodies) could significantly reverse multidrug resistance of hepatoma cells by targeting XIAP.

  7. Data show that mitochondrial X-linked inhibitor of apoptosis protein (XIAP) entry requires apoptosis regulatory proteins Bax (show BAX Antibodies) or Bak (show BAK1 Antibodies) through mitochondrial permeabilization and Smac/DIABLO (show DIABLO Antibodies) protein degradation.

  8. overexpression of XIAP confers cisplatin-resistance in ovarian carcinoma.

  9. The E3 ubiquitin ligase (show MUL1 Antibodies) activity of XIAP and cIAP1 (show BIRC2 Antibodies) activates NFkappaB (show NFKB1 Antibodies) signalling, leading to the direct binding of p65 (show GORASP1 Antibodies) to the promoter of Beclin 1 (show BECN1 Antibodies) and to its transcriptional activation and induction of autophagy.

  10. S-nitrosylation of XIAP Cys (show DNAJC5 Antibodies) 213 impairs the anti-caspase 3 (show CASP3 Antibodies) and anti-apoptotic function of XIAP.

Mouse (Murine) X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. Results show that XIAP binds to the C terminus of Ptch1 (show PTCH1 Antibodies) and mediates the death-dependent function of Ptch1 (show PTCH1 Antibodies).

  2. XIAP modulates ubiquitylation of RIP1 (show RALBP1 Antibodies) and suppresses RIP3 (show MPRIP Antibodies)-dependent cell death and inflammasome activation in response to TNF (show TNF Antibodies)-signaling in innate immune cells.

  3. XIAP deficiency selectively impaired B-cell chronic lymphocytic leukemia/lymphoma 10 (BCL10 (show BCL10 Antibodies))-mediated innate responses to dectin-1 (show CLEC7A Antibodies) ligands but did not affect responses to various Toll (show TLR4 Antibodies)-like receptor agonists.

  4. XIAP mRNA level was also reduced in the BRE (show BRE Antibodies)-depleted cells, but the level of reduction was less profound than that of the protein level. However, BRE (show BRE Antibodies) could not delay protein turnover of XIAP.

  5. Identify xIAP and cIAP1 (show BIRC2 Antibodies) as molecular targets of ceramide and show ceramide analog LCL85 is an effective sensitizer in overcoming resistance of metastatic colon and breast cancers to apoptosis induction to suppress metastasis in vivo.

  6. XIAP-/- DRG sensory neurons degenerate more rapidly and contain more active caspase-3 (show CASP3 Antibodies).

  7. XIAP ubiquitylates RIPK2 (show RIPK2 Antibodies) and recruits the linear ubiquitin chain assembly complex to NOD2 (show NOD2 Antibodies)

  8. XIAP is expressed in oligodendrocytes in vivo and in vitro. Increased XIAP expression is associated with protection against selected cell death pathways, whereas decreased expression increases oligodendroglial cell death.

  9. ARTS (Septin 4 (show SEPT4 Antibodies)) promotes apoptosis mainly through binding and antagonizing XIAP.

  10. A critical role is identified for XIAP in regulating neuronal apoptosis in neonatal brain injury.

XIAP Antigen Profile

Antigen Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.

Alternative names and synonyms associated with XIAP

  • X-linked inhibitor of apoptosis (XIAP) antibody
  • X-linked inhibitor of apoptosis (xiap) antibody
  • X-linked inhibitor of apoptosis (Xiap) antibody
  • 1110015C02Rik antibody
  • Aipa antibody
  • Api3 antibody
  • Birc4 antibody
  • hIAP-3 antibody
  • hIAP3 antibody
  • IAP-3 antibody
  • IAP3 antibody
  • ILP-1 antibody
  • ILP1 antibody
  • MIHA antibody
  • mXIAP antibody
  • riap3 antibody
  • XLP2 antibody
  • xxiap antibody

Protein level used designations for XIAP

X-linked inhibitor of apoptosis protein , baculoviral IAP repeat-containing 4 , baculoviral IAP-repeat containing protein 4 , Baculoviral IAP repeat-containing protein 4 , E3 ubiquitin-protein ligase XIAP , X-linked IAP , IAP-like protein , baculoviral IAP repeat-containing protein 4 , inhibitor of apoptosis protein 3 , IAP homolog A , IAP-3 , apoptosis inhibitor 3 , mIAP-3 , mIAP3 , RIAP-3 , apoptosis inhibitor protein 3

GENE ID SPECIES
442989 Canis lupus familiaris
594971 Xenopus (Silurana) tropicalis
331 Homo sapiens
11798 Mus musculus
63879 Rattus norvegicus
733235 Xenopus laevis
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