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XRCC4 Antibodies

(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].
XRCC4 antibody  (AA 1-336) XRCC4 antibody  (AA 1-336) XRCC4 antibody (AA 1-336) (ABIN3022382)

XRCC4 Reactivity: Human IF, IHC, WB Host: Rabbit Polyclonal unconjugated

XRCC4 antibody  (AA 1-336) XRCC4 antibody  (AA 1-336) XRCC4 antibody (AA 1-336) (ABIN1327721)

XRCC4 Reactivity: Human IF, IHC (p), WB Host: Mouse Polyclonal unconjugated

XRCC4 antibody  (Center) XRCC4 antibody  (Center) XRCC4 antibody (Center) (ABIN2857062)

XRCC4 Reactivity: Human ICC, IF, IP, IHC (p), WB Host: Rabbit Polyclonal unconjugated

XRCC4 Antibodies by Grade

Find XRCC4 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 Antibodies by Reactivity

Find XRCC4 Antibodies for a variety of species such as anti-Human XRCC4, anti-Rat XRCC4, anti-Mouse XRCC4. The species listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 Antibodies by Application

Find XRCC4 Antibodies validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

XRCC4 Antibodies by Host

Find XRCC4 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 Antibodies by Binding Specificity

Find XRCC4 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 Antibodies by Clonality

Find available monoclonal or polyclonal XRCC4 Antibodies. Click on a link to go to the corresponding products.

XRCC4 Antibodies by Clone

Find XRCC4 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 Antibodies by Conjugate

Find XRCC4 Antibodies with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular XRCC4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (4)
Cat. No. ABIN7259376
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IF, IHC (p), WB
Validations
  • (2)
  • (3)
Cat. No. ABIN2856695
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p), IP, WB
Validations
  • (3)
Cat. No. ABIN7211178
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p), IP, WB
Validations
  • (3)
Cat. No. ABIN7250143
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (3)
Cat. No. ABIN521432
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IP, WB
Validations
  • (2)
Cat. No. ABIN7189364
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (2)
Cat. No. ABIN3181156
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN3044561
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (2)
Cat. No. ABIN1386856
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN6266071
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (2)
Cat. No. ABIN2778273
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3029650
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7185671
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7150305
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (3)
Cat. No. ABIN967265
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our XRCC4 Antibodies

Zhang, Chang, Sun, Chen, Yang, Tang, Jing, Kang, He, Wu, Wei, Wang, Xu, Zhu, Shen, Zeng, Wang, Liu, Zhang, Mao, Jiang, Sun: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).

Wang, Sun, Zhu, Sun, Ma, Wang, Lu, Chen, Xu: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).

Chakraborty, Tapryal, Venkova, Horikoshi, Pandita, Sarker, Sarkar, Pandita, Hazra: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." in: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).

Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Zhu, Fisher, Bessho, Peng: "Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining." in: Nucleic acids research, Vol. 45, Issue 18, pp. 10583-10594, (2017) (PubMed).

van Sluis, McStay: "A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage." in: Genes & development, Vol. 29, Issue 11, pp. 1151-63, (2015) (PubMed).

Reid, Keegan, Leo-Macias, Watanabe, Strande, Chang, Oksuz, Fenyo, Lieber, Ramsden, Rothenberg: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).

Dong, Wang, Wang, Zhang, Zhu, Gao, Yang, Qin, Liang, Chen, Deng, Ning, Liang, Gao, Xu: "A stress-induced cellular aging model with postnatal neural stem cells." in: Cell death & disease, Vol. 5, pp. e1116, (2014) (PubMed).

Enervald, Du, Visnes, Björkman, Lindgren, Wincent, Borck, Colleaux, Cormier-Daire, van Gent, Pie, Puisac, de Miranda, Kracker, Hammarström, de Villartay, Durandy, Schoumans, Ström, Pan-Hammarström: "A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination." in: The Journal of experimental medicine, Vol. 210, Issue 12, pp. 2503-13, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Aliases for XRCC4 Antibodies

X-ray repair cross complementing 4 (XRCC4) Antibodies
X-ray repair complementing defective repair in Chinese hamster cells 4 (xrcc4) Antibodies
X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog (xrcc4.L) Antibodies
DNA ligase IV-binding protein (XRCC4) Antibodies
X-ray repair complementing defective repair in Chinese hamster cells 4 (Xrcc4) Antibodies
X-ray repair cross complementing 4 (Xrcc4) Antibodies
2310057B22Rik Antibodies
AW413319 Antibodies
AW545101 Antibodies
homolog of human DNA ligase iv-binding protein XRCC4 Antibodies
MGC81443 Antibodies
zgc:73312 Antibodies
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