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Browse our XIAP Proteins (XIAP)

Full name:
X-Linked Inhibitor of Apoptosis Proteins (XIAP)
On www.antibodies-online.com are 15 X-Linked Inhibitor of Apoptosis (XIAP) Proteins from 8 different suppliers available. Additionally we are shipping XIAP Antibodies (177) and XIAP Kits (19) and many more products for this protein. A total of 225 XIAP products are currently listed.
Synonyms:
1110015C02Rik, Aipa, Api3, Birc4, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, MIHA, mXIAP, riap3, XLP2, xxiap
list all proteins Gene Name GeneID UniProt
XIAP 331 P98170
XIAP 11798 Q60989
XIAP 63879 Q9R0I6

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XIAP Proteins (XIAP) by Origin

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More Proteins for XIAP Interaction Partners

Human X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. Study found a negative correlation between Smac (show DIABLO Proteins) and XIAP at the level of protein but not mRNA in non-small cell lung carcinoma (NSCLC) patients. Overexpressed XIAP could degrade through ubiquitination, the mature Smac (show DIABLO Proteins) inhibiting NSCLC apoptosis.

  2. Combined triple actions of the TRAIL, the IAPs inhibitor, AT406, and the c-FLIP (show CFLAR Proteins) expression inhibitor, rocaglamide (ART), markedly improve TRAIL-induced apoptotic effects in most solid cancer cell lines through the activation of an extrinsic apoptosis pathway

  3. we identified X-linked inhibitor of apoptosis protein (XIAP) as a direct target of miR (show MLXIP Proteins)-509-3p.

  4. MiR (show MLXIP Proteins)-874 inhibits growth, increases apoptosis and enhances chemosensitivity in CRC (show CALR Proteins) cells by targeting XIAP.

  5. Data show that X-linked inhibitor of apoptosis protein (XIAP) mRNA and protein expression increased, whereas XIAP-associated factor 1 (XAF1 (show XAF1 Proteins)) mRNA and protein expression decreased with the growth of radiation dose and exposure time.

  6. We demonstrated that, while depletion of XIAP attenuates cell transformation, elevated USP11 significantly promotes the tumor colony formation through stabilization of XIAP.

  7. High XIAP expression is associated with ovarian cancer.

  8. miR (show MLXIP Proteins)-24 plays an important role in regulating the cell survival of periodontal ligament cells through targeting XIAP.

  9. Herein, CEUS imaging during cancer treatment played an important role in evaluating the therapeutic effects of XIAP siRNA ultrasound-responsive microbubble are a promising theranostic system for cancer gene therapy.

  10. herefore targeting XIAP and NF-kappaB (show NFKB1 Proteins) pathways simultaneously can be investigated in more detail to make use of embelin and celastrol as a combination therapy of cancer

Mouse (Murine) X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. Results show that XIAP binds to the C terminus of Ptch1 (show PTCH1 Proteins) and mediates the death-dependent function of Ptch1 (show PTCH1 Proteins).

  2. XIAP modulates ubiquitylation of RIP1 (show RALBP1 Proteins) and suppresses RIP3-dependent cell death and inflammasome activation in response to TNF (show TNF Proteins)-signaling in innate immune cells.

  3. XIAP deficiency selectively impaired B-cell chronic lymphocytic leukemia/lymphoma 10 (BCL10 (show BCL10 Proteins))-mediated innate responses to dectin-1 (show CLEC7A Proteins) ligands but did not affect responses to various Toll (show TLR4 Proteins)-like receptor agonists.

  4. XIAP mRNA level was also reduced in the BRE (show BRE Proteins)-depleted cells, but the level of reduction was less profound than that of the protein level. However, BRE (show BRE Proteins) could not delay protein turnover of XIAP.

  5. Identify xIAP and cIAP1 (show BIRC2 Proteins) as molecular targets of ceramide and show ceramide analog LCL85 is an effective sensitizer in overcoming resistance of metastatic colon and breast cancers to apoptosis induction to suppress metastasis in vivo.

  6. XIAP-/- DRG sensory neurons degenerate more rapidly and contain more active caspase-3 (show CASP3 Proteins).

  7. XIAP ubiquitylates RIPK2 and recruits the linear ubiquitin chain assembly complex to NOD2

  8. XIAP is expressed in oligodendrocytes in vivo and in vitro. Increased XIAP expression is associated with protection against selected cell death pathways, whereas decreased expression increases oligodendroglial cell death.

  9. ARTS (Septin 4 (show SEPT4 Proteins)) promotes apoptosis mainly through binding and antagonizing XIAP.

  10. A critical role is identified for XIAP in regulating neuronal apoptosis in neonatal brain injury.

XIAP Protein Profile

Protein Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.

Alternative names and synonyms associated with XIAP

  • X-linked inhibitor of apoptosis (XIAP)
  • X-linked inhibitor of apoptosis (xiap)
  • X-linked inhibitor of apoptosis (Xiap)
  • 1110015C02Rik protein
  • Aipa protein
  • Api3 protein
  • Birc4 protein
  • hIAP-3 protein
  • hIAP3 protein
  • IAP-3 protein
  • IAP3 protein
  • ILP-1 protein
  • ILP1 protein
  • MIHA protein
  • mXIAP protein
  • riap3 protein
  • XLP2 protein
  • xxiap protein

Protein level used designations for XIAP

X-linked inhibitor of apoptosis protein , baculoviral IAP repeat-containing 4 , baculoviral IAP-repeat containing protein 4 , Baculoviral IAP repeat-containing protein 4 , E3 ubiquitin-protein ligase XIAP , X-linked IAP , IAP-like protein , baculoviral IAP repeat-containing protein 4 , inhibitor of apoptosis protein 3 , IAP homolog A , IAP-3 , apoptosis inhibitor 3 , mIAP-3 , mIAP3 , RIAP-3 , apoptosis inhibitor protein 3

GENE ID SPECIES
442989 Canis lupus familiaris
594971 Xenopus (Silurana) tropicalis
331 Homo sapiens
11798 Mus musculus
63879 Rattus norvegicus
733235 Xenopus laevis
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