Browse our anti-HCN1 (HCN1) Antibodies

Full name:
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 Antibodies (HCN1)
On are 101 Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) Antibodies from 19 different suppliers available. Additionally we are shipping HCN1 Proteins (6) and many more products for this protein. A total of 108 HCN1 products are currently listed.
BCNG-1, Bcng1, C630013B14Rik, HAC-2, HAC2

Most Popular Reactivities for anti-HCN1 (HCN1) Antibodies

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anti-Human HCN1 Antibodies:

anti-Rat (Rattus) HCN1 Antibodies:

anti-Mouse (Murine) HCN1 Antibodies:

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Top referenced anti-HCN1 Antibodies

  1. Human Monoclonal HCN1 Primary Antibody for AA, IHC - ABIN2483964 : Zong, Eckert, Yuan, Wahl-Schott, Abicht, Fang, Li, Mistrik, Gerstner, Much, Baumann, Michalakis, Zeng, Chen, Biel: A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase. in The Journal of biological chemistry 2005 (PubMed)

  2. Human Polyclonal HCN1 Primary Antibody for IHC (p), WB - ABIN658149 : Odefrey, Stone, Gurrin, Byrnes, Apicella, Dite, Cawson, Giles, Treloar, English, Hopper, Southey,: Common genetic variants associated with breast cancer and mammographic density measures that predict disease. in Cancer research 2010 (PubMed)

More Antibodies against HCN1 Interaction Partners

Human Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) interaction partners

  1. Study presents cryo-electron microscopy structures of the human HCN1 channel in the absence and presence of cAMP at 3.5 A resolution. HCN channels contain a K(+) channel (show KCNC4 Antibodies) selectivity filter-forming sequence from which the amino acids create a unique structure that explains Na(+) and K(+) permeability.

  2. A new mode of regulating HCN1 trafficking: through the use of a di-arginine ER retention signal that monitors processing of the channel in the early secretory pathway.

  3. de novo HCN1 point mutations cause a recognizable early-onset epileptic encephalopathy in humans

  4. acute abrogation of HCN1-FLNa (show FLNA Antibodies) interaction in neurons, with the use of decoy peptides that mimic the FLNa (show FLNA Antibodies)-binding domain of HCN1, abolishes the punctate distribution of HCN1 channels in neuronal cell bodies

  5. Studies suggest that HCN1 channels may be therapeutic targets for treatment of depressive disorders.

  6. Wild-type presynaptic HCN1 channel function is persistently decreased following seizures.

  7. HCN1 channels make an important contribution to the maintenance of spontaneous burst activity in embryonic cortical neuron cultures.

  8. Hyperpolarization-activated currents are smaller and slower, input resistances are higher, and membrane time constants are longer in HCN1-deficient than in HCN1-expressing neurons of the ventral cochlear nucleus.

  9. Genetic analysis in 48 Sudden unexpected death in epilepsy cases identified six novel and three previously reported nonsynonymous (amino acid changing) variants in HCN1 , HCN2 (show HCN2 Antibodies), HCN3 (show HCN3 Antibodies) and HCN4 (show HCN4 Antibodies).

  10. increasing cAMP levels in cells antagonized the up-regulation of HCN1 channels mediated by a TRIP8b (show PEX5L Antibodies) construct binding the CNBD exclusively.

Mouse (Murine) Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) interaction partners

  1. HCN channels play a critical role in the separation of overlapping movement responses and allow for successful reaching behaviours. These data provide a novel mechanism for the encoding of multiple movement responses within shared networks of motor cortex. This mechanism supports a viewpoint of primary motor cortex as a site of dynamic integration for behavioural output

  2. The study thus identifies novel candidate QTGs HCN1 that may contribute to variation in emotional learning in mice.

  3. Data show that prostaglandin E2 receptor EP3 subtype (EP3 (show PTGER3 Antibodies)) was expressed in the interstitial cells of Cajal (ICCs) of the bladder and activated hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

  4. Data show that KCNJ15 inward rectifier potassium channel and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents are changed in Trisomic neuron.

  5. We investigated the effects of an additional genetic deletion of HCN1 on the function and survival of photoreceptors in a mouse model of CNGB1 (show CNGB1 Antibodies)-linked retinitis pigmentosa (RP).

  6. in the absence of HCN1-mediated feedback, the amplitude of rod signals remains at high levels for a prolonged period of time, leading to saturation of the retinal pathways.

  7. These results demonstrate that the CB1R (show CNR1 Antibodies)-Ih pathway in the hippocampus is obligatory for the action of cannabinoids on long-term potentiation and spatial memory formation.

  8. Resilience to tinnitus is developed in mice that show a re-emergence of KCNQ2/3 channel activity and a reduction in HCN channel activity.

  9. HCN1, HCN2 (show HCN2 Antibodies), and HCN4 (show HCN3 Antibodies) subunits may have distinct physiological roles in the developing hippocampus.

  10. Forebrain HCN1 channels contribute to hypnotic and amnestic effects of volatile anesthetics, but do not contribute to immobilizing actions.

HCN1 Antigen Profile

Antigen Summary

The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes.

Alternative names and synonyms associated with HCN1

  • hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (hcn1) antibody
  • hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (HCN1) antibody
  • hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 (Hcn1) antibody
  • hyperpolarization-activated, cyclic nucleotide-gated K+ 1 (Hcn1) antibody
  • BCNG-1 antibody
  • Bcng1 antibody
  • C630013B14Rik antibody
  • HAC-2 antibody
  • HAC2 antibody

Protein level used designations for HCN1

hyperpolarization activated cyclic nucleotide-gated potassium channel 1 , brain cyclic nucleotide gated channel 1 , brain cyclic nucleotide-gated channel 1 , potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 , hyperpolarization-activated cyclic nucleotide-gated channel 1 , rbHCN1 , BCNG-1 , HAC-2 , hyperpolarization-activated cation channel 2

100564901 Anolis carolinensis
348980 Homo sapiens
100008732 Oryctolagus cuniculus
84390 Rattus norvegicus
15165 Mus musculus
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