Browse our ATG3 Proteins (ATG3)

Full name:
ATG3 Autophagy Related 3 Homolog (S. Cerevisiae) Proteins (ATG3)
On are 30 ATG3 Autophagy Related 3 Homolog (S. Cerevisiae) (ATG3) Proteins from 6 different suppliers available. Additionally we are shipping ATG3 Antibodies (197) and ATG3 Kits (2) and many more products for this protein. A total of 238 ATG3 products are currently listed.
2610016C12Rik, APG3, APG3-LIKE, Apg3l, ATATG3, atg3, Atg3l, im:6910145, K11J9.1, K11J9_1, PC3-96, PIG-1, Pig1, wu:fb15g12, zgc:64156
list all proteins Gene Name GeneID UniProt
ATG3 64422 Q9NT62
ATG3 67841 Q9CPX6
ATG3 171415 Q6AZ50

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Human ATG3 Autophagy Related 3 Homolog (S. Cerevisiae) (ATG3) interaction partners

  1. Our data demonstrate that HOTAIR promotes the activation of autophagy in HCC (show FAM126A Proteins) cells by upregulating the expression of the autophagy-related genes ATG3 and ATG7 (show ATG7 Proteins).

  2. ATG3 upregulation contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells

  3. Hidden Markov models were used to detect protein homology among the flexible regions of Atg3 homologs and importance of conserved regions evaluated by performing affinity capture experiments with human Atg3 deletion constructs; binding studies and competition experiments demonstrate that overlapping sites in the Atg3FR are important for E3 binding and E1 binding.

  4. The region of human ATG3 that interacts with ATG7 (show ATG7 Proteins) is precisely identified using nuclear magnetic resonance.

  5. ATG3 gene and its gene family may play an important role in transformation of myelodysplastic syndrome.

  6. Lipidation of the LC3 (show MAP1LC3A Proteins)/GABARAP (show GABARAP Proteins) family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.

  7. 13 residues of the ATG3 fragment form a short beta-strand followed by an alpha-helix on a surface area that is an exclusive binding site for ATG12.

  8. caspase-8 (show CASP8 Proteins) overexpression led to Atg3 degradation and this event depended on caspase-8 (show CASP8 Proteins) enzymatic activity

  9. These results unveil a role for ATG12-ATG3 in mitochondrial homeostasis and implicate the ATG12 conjugation system in cellular functions distinct from the early steps of autophagosome formation.

  10. Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16 (show GABARAPL2 Proteins), GABARAP (show GABARAP Proteins), and MAP-LC3 (show MAP1LC3A Proteins), and facilitates the conjugation of hApg12p to hApg5p

Mouse (Murine) ATG3 Autophagy Related 3 Homolog (S. Cerevisiae) (ATG3) interaction partners

  1. miR (show MLXIP Proteins)-495 targets ATG3 and regulates its protein levels under starvation conditions. miR (show MLXIP Proteins)-495 also inhibits starvation-induced autophagy by decreasing the number of autophagosomes.

  2. ATG12 (show ATG12 Proteins)-ATG3 interacts with Alix (show PDCD6IP Proteins) to promote basal autophagic flux and late endosome function.

  3. Atg3 expression, similar to Atg5 expression, is required for Immunity Related GTPases and Guanylate binding proteins to dock to pathogen-containing vacuoles.

  4. Vaccinia virus actively disrupts the cellular autophagy through a novel molecular mechanism that is associated with aberrant LC3 (show MAP1LC3A Proteins) lipidation and a direct conjugation between ATG12 (show ATG12 Proteins) and ATG3.

  5. The model and biochemical data provide a rationale for Atg7 (show ATG7 Proteins) dimerization: Atg8 (show MAP1LC3B Proteins) is transferred in trans from the catalytic cysteine of one Atg7 (show ATG7 Proteins) protomer to Atg3 bound to the N-terminal domain of the opposite Atg7 (show ATG7 Proteins) protomer within the homodimer.

ATG3 Protein Profile

Protein Summary

Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy (Tanida et al., 2002

Alternative names and synonyms associated with ATG3

  • APG3 autophagy 3-like (apg3l)
  • ATG3 autophagy related 3 homolog (S. cerevisiae) (ATG3)
  • autophagy related 3 (ATG3)
  • autophagy related 3 (Atg3)
  • autophagy-related protein 3 (ATG3)
  • similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy (ATG3)
  • 2610016C12Rik protein
  • APG3 protein
  • APG3-LIKE protein
  • Apg3l protein
  • ATATG3 protein
  • atg3 protein
  • Atg3l protein
  • im:6910145 protein
  • K11J9.1 protein
  • K11J9_1 protein
  • PC3-96 protein
  • PIG-1 protein
  • Pig1 protein
  • wu:fb15g12 protein
  • zgc:64156 protein

Protein level used designations for ATG3

APG3-like , autophagy-related protein 3 , ubiquitin-like-conjugating enzyme ATG3 , 2610016C12Rik , ATG3 autophagy related 3 homolog , hApg3 , autophagy-related 3 , Apg3p , preconditioning-inducible gene 1 protein , potential E2-like lipid conjugating enzyme Atg3

336632 Danio rerio
508571 Bos taurus
64422 Homo sapiens
67841 Mus musculus
418369 Gallus gallus
478564 Canis lupus familiaris
171415 Rattus norvegicus
836271 Arabidopsis thaliana
3639390 Candida albicans SC5314
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