Browse our LAMP2 Proteins (LAMP2)

Full name:
Lysosomal-Associated Membrane Protein 2 Proteins (LAMP2)
On www.antibodies-online.com are 27 Lysosomal-Associated Membrane Protein 2 (LAMP2) Proteins from 9 different suppliers available. Additionally we are shipping LAMP2 Antibodies (426) and LAMP2 Kits (18) and many more products for this protein. A total of 483 LAMP2 products are currently listed.
Synonyms:
CD107b, DKFZp459J126, Lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, lamp2, LAMPB, LGP-B, LGP110, Mac3
list all proteins Gene Name GeneID UniProt
LAMP2 16784 P17047
LAMP2 3920 P13473
LAMP2 24944  

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LAMP2 Proteins (LAMP2) by Origin

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Top referenced LAMP2 Proteins

  1. Human LAMP2 Protein expressed in Wheat germ - ABIN1309134 : Roth, Brown, Smith, Badhwar, Parente, Chung, Bunch, McGregor, Hogan, Hu, Yang, Berg, Niles, Jennette, Preston, Falk: Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis. in Journal of the American Society of Nephrology : JASN 2012 (PubMed)
    Show all 2 references for 1309134

More Proteins for LAMP2 Interaction Partners

Mouse (Murine) Lysosomal-Associated Membrane Protein 2 (LAMP2) interaction partners

  1. The results presented here show the major role of LAMP-2 in caveolin traffic and membrane repair and consequently in T. cruzi invasion.

  2. The up-regulation of Rab11 (show RAB11A Proteins), Rab7 (show RAB7A Proteins), or RILP (show RILP Proteins), but not its truncated form RILP (show RILP Proteins)-C33 (show CD82 Proteins), rescued LAMP2A-defective trafficking in cystinosis, whereas dominant-negative Rab11 (show RAB11A Proteins) or Rab7 (show RAB7A Proteins) impaired LAMP2A trafficking.

  3. LAMP-2 in the central nervous system has a possible role in the degradation of the various macromolecules in lysosomes and an additional function concerning protection from oxidative stress, especially in the substantia nigra.

  4. The absence of LAMP-2 in murine brain led to inflammation and abnormal behavior, including motor deficits and impaired learning.

  5. Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure.

  6. These results suggest that VPS35 deficiency or mutation promotes Parkinson Disease (PD) pathogenesis, and reveals a crucial pathway, VPS35-Lamp2a-alpha-synuclein, to prevent PD pathogenesis.

  7. LAMP proteins retain TAPL (show ABCB9 Proteins) on the limiting membrane of endosomes and prevent its sorting to intraluminal vesicles.

  8. Restoration of lysosome-associated membrane protein-2 levels synergizes with partial BECLIN-1 (show BECN1 Proteins) knockdown to restore autophagosome processing and to attenuate cell death after hypoxia-reoxygenation.

  9. results suggest that LAMP-2, its luminal domain in particular, plays a critical role in endosomal cholesterol transport and that this is distinct from the chaperone-mediated autophagy function of LAMP-2

  10. Using LAMP1 (show LAMP1 Proteins)/2 knock out cells the authors show that these two proteins are important for Trypanosoma cruzi infection of host cells, both in entrance and intracellular development, conceivably by being the major source of sialic acid for Trypanosoma cruzi.

Human Lysosomal-Associated Membrane Protein 2 (LAMP2) interaction partners

  1. The authors show here that human LAMP1 (show LAMP1 Proteins) and LAMP2 bind cholesterol in a manner that buries the cholesterol 3beta-hydroxyl group; they also bind tightly to NPC1 (show NPC1 Proteins) and NPC2 (show NPC2 Proteins) proteins that export cholesterol from lysosomes.

  2. identified LAMP-2 as an endocytic receptor on monocyte-derived dendritic cells (MoDC) that routes cargo into unusual Ag processing pathways, which reduces surface expression of Ag-derived peptides while selectively enriching Ag within immunogenic exosome; this novel pathway has implications for the initiation of immune responses both locally and at distant sites

  3. downregulation of FUT1 (show FUT1 Proteins), which leads to the perinuclear localization of LAMP-1 (show LAMP1 Proteins) and 2, is correlated with increased rate of autophagic flux by decreasing mTOR (show FRAP1 Proteins) signaling and increasing autolysosome formation.

  4. The results provide a new insight that LAMP-2 contributes to the ROS (show ROS1 Proteins) clearance and cell death induced by Zn(2+) treatment, which would help us to get a better understanding of Zn(2+)-induced toxicity in respiratory system.

  5. Genetic analysis identified 2 novel LAMP2 gene mutations. In Family A, a G-A transition (c.962G > A) leading to a nonsense mutation at codon 321 (p.Trp321Ter), and in Family B, a one-nucleotide insertion (c.973insC) leading to a full frame-shift (p.Pro324+24X) was detected in exon 8 of the LAMP2 gene.

  6. the assembly modes of LAMP-1 (show LAMP1 Proteins) and LAMP-2 are different, which may underlie their distinct functions

  7. intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73 (show HSPA8 Proteins), key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.

  8. 3 novel nonsense mutations (p.Q240X, p.S250X, and p.G22X) were found in LAMP2 associated with early onset Danon disease with hypertrophic cardiomyopathy. LAMP2 expression was absent in both cardiac and skeletal muscle samples of the first proband and severely decreased LAMP2 expression in the skeletal muscle samples of the second proband.

  9. Increased expression of LAMP2 has been observed in peripheral blood mononuclear cells of coronary artery disease patients compared to the control group.

  10. Knockdown of LAMP2A, a CMA-related protein, and TSG101 (show TSG101 Proteins), an mA-related protein, significantly but only partially decreased the punctate accumulation of GAPDH (show GAPDH Proteins)-HT in AD293 cells and primary cultured rat cortical neurons.

LAMP2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.

Alternative names and synonyms associated with LAMP2

  • lysosomal-associated membrane protein 2 (LAMP2)
  • lysosomal-associated membrane protein 2 (lamp2)
  • Lysosome-associated membrane glycoprotein 2 (lamp2)
  • lysosomal-associated membrane protein 2 (LOC100218047)
  • lysosomal-associated membrane protein 2 (LOC100222683)
  • lysosomal membrane glycoprotein B (Lgpb)
  • lysosomal-associated membrane protein 2 (Lamp2)
  • CD107b protein
  • DKFZp459J126 protein
  • Lamp-2 protein
  • Lamp-2a protein
  • Lamp-2b protein
  • Lamp-2c protein
  • lamp2 protein
  • LAMPB protein
  • LGP-B protein
  • LGP110 protein
  • Mac3 protein

Protein level used designations for LAMP2

lysosome-associated membrane glycoprotein 2 , lysosomal-associated membrane protein 2 , Lysosome-associated membrane glycoprotein 2 , lysosome-associated membrane glycoprotein 2-like , CD107 antigen-like family member B , Lysosome-associated membrane protein 2 , LGP-B , Lamp II , lysosomal membrane glycoprotein 2 , lysosomal membrane glycoprotein type B , lysosome-associated membrane protein 2 , lysosome-associated membrane protein-2 , LAMP-2 , LGP-110 , LGP-96 , lysosome-associated membrane glycoprotein LAMP-2

GENE ID SPECIES
481037 Canis lupus familiaris
447742 Xenopus laevis
529148 Bos taurus
695379 Macaca mulatta
737597 Pan troglodytes
779509 Xenopus (Silurana) tropicalis
100154598 Sus scrofa
100169945 Felis catus
100194781 Salmo salar
100218047 Taeniopygia guttata
100222683 Taeniopygia guttata
100398116 Callithrix jacchus
100173702 Pongo abelii
100591960 Nomascus leucogenys
100689316 Cricetulus griseus
16784 Mus musculus
3920 Homo sapiens
24944 Rattus norvegicus
414800 Gallus gallus
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