LAMP2 Protein (His tag)
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- Target See all LAMP2 Proteins
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This LAMP2 protein is labelled with His tag.
- Purpose
- Recombinant Human LAMP2/CD107b Protein (His Tag)(Active)
- Sequence
- Leu29-Ile375
- Characteristics
- Recombinant Human Lysosome-Associated Membrane Glycoprotein 2 is produced by our Mammalian expression system and the target gene encoding Leu29-Ile375 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human LGALS3(Cat: PKSH032474) at 1.5μg/ml(100 μl/well) can bind Human LAMP2-His. The ED50 of Human LAMP2-His is 12.73 ug/ml .
- Top Product
- Discover our top product LAMP2 Protein
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Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 30-127) protein (GST tag)
LAMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 34-231) protein (His-IF2DI Tag)LAMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Lysosomal-Associated Membrane Protein 2 (LAMP2) protein (His tag)LAMP2 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-375) protein (His tag)Crystallography grade LAMP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 26-379) protein (His tag)Crystallography grade LAMP2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-410) protein (rho-1D4 tag)Crystallography grade LAMP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 26-415) protein (rho-1D4 tag)Crystallography grade LAMP2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Alternative Name
- LAMP2/CD107b (LAMP2 Products)
- Synonyms
- CD107b Protein, LAMP-2 Protein, LAMPB Protein, LGP110 Protein, Lamp-2 Protein, Lamp-2a Protein, Lamp-2b Protein, Lamp-2c Protein, Mac3 Protein, cd107b Protein, lamp-2 Protein, lampb Protein, LAMP2 Protein, lamp2 Protein, DKFZp459J126 Protein, LGP-B Protein, sb:cb587 Protein, wu:fb14a06 Protein, zgc:103532 Protein, lysosomal associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 S homeolog Protein, lysosomal membrane glycoprotein 2 Protein, LAMP2 Protein, Lamp2 Protein, lamp2.S Protein, lamp2 Protein
- Background
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Background: Lysosomal Associated Membrane Protein 2 (LAMP2) is a major component of lysosomal membranes. LAMP2 is a transmembrane glycoprotein about 110 kDa. Mature human LAMP2 consists of a 347 amino acid (aa) intralumenal domain, a 24 aa transmembrane segment, and a 35 aa cytoplasmic tail . The lumenal domain is organized into two heavily N-glycosylated regions. Alternate splicing generates a human LAMP2 isoform (LAMP2B) with a substituted juxtamembrane lumenal region, cytoplasmic tail and transmenmbrane segment.LAMP2 itself can cleavage lysosomal luminal domain and degradation lysosomal. In the help of chaperone HSC73,LAMP2 mediates the lysosomal uptake in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles.
Synonym: Lysosome-Associated Membrane Glycoprotein 2, LAMP-2, Lysosome-Associated Membrane Protein 2, CD107 Antigen-Like Family Member B, CD107b, LAMP2
- Molecular Weight
- 33.9 kDa
- UniProt
- P13473
- Pathways
- Autophagy
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