Browse our SCP2 (SCP2) ELISA Kits

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Sterol Carrier Protein 2 ELISA Kits (SCP2)
On are 19 Sterol Carrier Protein 2 (SCP2) ELISA Kits from 1 different suppliers available. Additionally we are shipping SCP2 Antibodies (135) and SCP2 Proteins (18) and many more products for this protein. A total of 182 SCP2 products are currently listed.
AA409774, AA409893, AI586070, C76618, C79031, D10Ertd73e, NLTP, ns-LTP, NSL-TP, NSLIPTR, OS-4, OS4, PLTP, SCP-2, SCP-CHI, SCP-X, SCP2, SCPx

More ELISA Kits for SCP2 Interaction Partners

Mouse (Murine) Sterol Carrier Protein 2 (SCP2) interaction partners

  1. Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells

  2. L-FABP (show FABP1 ELISA Kits) was more important in hepatic retention of bile acids, while SCP-2/SCP-x more broadly affected biliary bile acid and phospholipid levels.

  3. Loss of L-FABP (show FABP1 ELISA Kits) and SCP-2 (show CRISP3 ELISA Kits), or both induces hepatic lipid accumulation in female mice and mimics non-alcoholic fatty liver disease.

  4. CTDSP2 induces p21(Cip1/Waf1 (show CDKN1A ELISA Kits)) through increasing the activity of Ras.

  5. SCP-2/SCP-x may function more in formation and biliary secretion of bile acid, with less impact on hepatic uptake or biliary secretion of HDL (show HSD11B1 ELISA Kits)-cholesterol

  6. liver fatty acid-binding protein, the single most prevalent hepatic cytosolic protein that binds cholesterol, was upregulated twofold in SCP-2 (show CRISP3 ELISA Kits) null hepatocytes

  7. SCP-2 expression plays a significant role in HDL-mediated cholesterol efflux by regulating the size of rapid vs. slow cholesterol efflux pools and/or eliciting concomitant upregulation of L-FABP in cultured primary hepatocytes.

  8. Effect of Scp2 (show CRISP3 ELISA Kits) expression on the rate of sterol transfer from lysosomal membranes, and lysosomal membrane lipid distribution.

  9. Data show that expression of sterol carrier protein-2 (SCP-2) increased fatty acid uptake and targeted fatty acid to unique lipid pools, suggesting that SCP-2 (show CRISP3 ELISA Kits) may effectively serve as universal fatty acid binding and trafficking protein.

  10. Results suggest a key regulatory role for sterol carrier protein-2 in hepatic lipid metabolism.

Human Sterol Carrier Protein 2 (SCP2) interaction partners

  1. We (1) analyzed the structural basis of the fold and the classification of SCP2 domains; (2) identified structure-determined sequence features; (3) compared the lipid binding cavity of SCP2 and other lipid binding proteins; (4) surveyed proposed mechanisms of SCP2 mediated lipid transfer between membranes; and (5) uncovered a possible new function of the SCP2 domain as a protein-protein recognition device.

  2. imported protein sterol carrier protein 2 (SCP2) occupies only a subregion of larger peroxisomes, highlighting the heterogeneous distribution of proteins even within the peroxisome.

  3. Mice harboring a deletion of the Scp2 locus present a modulated diurnal accumulation of lipids in the liver and a perturbed activation of several signaling pathways including PPARalpha (show PPARA ELISA Kits), SREBP, LRH-1 (show NR5A2 ELISA Kits), TORC1 (show CRTC1 ELISA Kits) and its upstream regulators.

  4. We conclude that SCP-2 is a low affinity binding protein for arachidonylethanolamine that can facilitate its cellular uptake but does not contribute significantly to intracellular sequestration of AEA.

  5. The Peroxisomal targeting signal 1 in Scp2 is autonomous and is essential for binding to pex5 (show PEX5 ELISA Kits).

  6. cellular SCP-2 not only binds and translocates cholesterol but also cholesterol hydroperoxides, thus expanding their redox toxicity and signaling ranges under oxidative stress conditions

  7. Statistical analysis indicated that six genes, NFATC2, SCP2, CACNA1C, TCRA, POLE, and FAM3D, were associated with narcolepsy.

  8. data for the first time showed that while the N-terminal membrane binding domain of SCP(2) was itself inactive in mediating intermembrane sterol transfer, it nevertheless potentiated the ability of SCP(2) to enhance sterol transfer

  9. SCP2 in the cellular defense against oxidative damage and found that a fluorescent fatty acid analog bound to SCP2 is protected against H2O2/Cu2+-induced oxidative damage

  10. Overexpression of human SCP-2 in murine fibroblasts significantly alters the sterol dynamics of caveolae/lipid rafts, but not nonlipid raft domains, to facilitate retention of cholesterol within the cell.

Cow (Bovine) Sterol Carrier Protein 2 (SCP2) interaction partners

  1. By trafficking cholesterol hydroperoxides and phospholipid hydroperoxides in addition to parent lipids, SCP2 may exacerbate cell injury under oxidative stress conditions. [sterol carrier protein 2, SCP2, nonspecific lipid transfer protein]

SCP2 Antigen Profile

Antigen Summary

This gene encodes two proteins (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Alternative names and synonyms associated with SCP2

  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (Ctdsp2) Elisa Kit
  • phospholipid transfer protein homolog1 (plt1) Elisa Kit
  • sterol carrier protein 2 (SCP2) Elisa Kit
  • sterol carrier protein 2 (Scp2) Elisa Kit
  • sterol carrier protein 2, liver (Scp2) Elisa Kit
  • AA409774 Elisa Kit
  • AA409893 Elisa Kit
  • AI586070 Elisa Kit
  • C76618 Elisa Kit
  • C79031 Elisa Kit
  • D10Ertd73e Elisa Kit
  • NLTP Elisa Kit
  • ns-LTP Elisa Kit
  • NSL-TP Elisa Kit
  • NSLIPTR Elisa Kit
  • OS-4 Elisa Kit
  • OS4 Elisa Kit
  • PLTP Elisa Kit
  • SCP-2 Elisa Kit
  • SCP-CHI Elisa Kit
  • SCP-X Elisa Kit
  • SCP2 Elisa Kit
  • SCPx Elisa Kit

Protein level used designations for SCP2

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 , nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2) (Protein OS-4) , small C-terminal domain phosphatase 2 , CL468_1 , CL468_1(249) , CL468_1_ov , LTP , allergen Zea m 14 , non-specific lipid-transfer protein , propanoyl-CoA C-acyltransferase , sterol carrier protein X , NSL-TP , SCP-2 , SCP-X , SCP-chi , Sterol carrier protein 2, liver , sterol carrier protein-2 , SCPX , sterol carrier protein 2, liver , nonspecific lipid transfer protein

52468 Mus musculus
542231 Zea mays
6342 Homo sapiens
479564 Canis lupus familiaris
397439 Sus scrofa
508918 Bos taurus
25541 Rattus norvegicus
396550 Gallus gallus
100008683 Oryctolagus cuniculus
100728738 Cavia porcellus
101116445 Ovis aries
20280 Mus musculus
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