Browse our anti-AVPR2 (AVPR2) Antibodies

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anti-Arginine Vasopressin Receptor 2 Antibodies (AVPR2)
On are 66 Arginine Vasopressin Receptor 2 (AVPR2) Antibodies from 17 different suppliers available. Additionally we are shipping AVPR2 Kits (3) and and many more products for this protein. A total of 75 AVPR2 products are currently listed.
list all antibodies Gene Name GeneID UniProt
AVPR2 554 P30518
AVPR2 12000 O88721
AVPR2 25108 Q00788

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Top referenced anti-AVPR2 Antibodies

  1. Human Polyclonal AVPR2 Primary Antibody for WB - ABIN2801893 : Seibold, Brabet, Rosenthal, Birnbaumer: Structure and chromosomal localization of the human antidiuretic hormone receptor gene. in American journal of human genetics 1992 (PubMed)
    Show all 5 references for 2801893

  2. Human Polyclonal AVPR2 Primary Antibody for IF, ELISA - ABIN1536014 : Birnbaumer, Seibold, Gilbert, Ishido, Barberis, Antaramian, Brabet, Rosenthal: Molecular cloning of the receptor for human antidiuretic hormone. in Nature 1992 (PubMed)
    Show all 2 references for 1536014

  3. Human Polyclonal AVPR2 Primary Antibody for WB - ABIN929264 : Canal, Wilkinson, Cooper, Wraith, Wynn, Bigger: Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB. in Behavioural brain research 2010 (PubMed)

  4. Human Polyclonal AVPR2 Primary Antibody for ELISA - ABIN409117 : Mutig, Paliege, Kahl, Jöns, Müller-Esterl, Bachmann: Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL. in American journal of physiology. Renal physiology 2007 (PubMed)

More Antibodies against AVPR2 Interaction Partners

Human Arginine Vasopressin Receptor 2 (AVPR2) interaction partners

  1. An overview of AVPR2 mutations in genetic forms of nephrogenic diabetes insipidus (review)

  2. this case report describes a case of congenital nephrogenic diabetes insipidus with an AVPR2 gene I324M missense mutation; this is the first report of this mutation in patients with congenital nephrogenic diabetes insipidus

  3. the canceling of the desensitization effect of OPC51803 by the pharmacochaperone effect after long-term treatment may produce sustainable signaling, and thus pharmacochaperone agonists such as OPC51803 may serve as promising therapeutics for NDI caused by misfolded V2R mutants.

  4. AVPR2 missense mutation is associated with nephrogenic diabetes insipidus.

  5. Data suggest that the congenital congenital nephrogenic diabetes insipidus (NDI) in the patient, his mother and grandmother was probably due to mutation of the arginine vasopressin receptor 2 (AVPR2) gene.

  6. a splice site mutation in AVPR2 leads to partial X-linked NDI in two brothers.

  7. A heterozygous deletion in exon 1 of the AVPR2 gene is associated with nephrogenic diabetes insipidus.

  8. In this study, we identified and characterized a new gain-of function mutation of the V2R, which leads to nephrogenic syndrome of inappropriate diuresis.

  9. We present a novel mutation in codon 137 within AVPR2 with substitution of glycine for arginine in male dizygotic twins.

  10. Rescue of the N321K-V2R function by Val(4)-desmopressin action in nephrogenic diabetes insipidus.

Pig (Porcine) Arginine Vasopressin Receptor 2 (AVPR2) interaction partners

  1. Type 2 vasopressin (show AVP Antibodies) receptor (V2R) is in primary cilia of renal epithelial cells. There is also a functional cAMP-signaling pathway, which targets ciliary channel function and may help control the sensory function of the primary cilium.

Mouse (Murine) Arginine Vasopressin Receptor 2 (AVPR2) interaction partners

  1. Data show that upon heteromer formation with secretin receptor (SCTR (show SCTR Antibodies)), R137H, a nephrogenic diabetes insipidus (NDI)-causing vasopressin (show AVP Antibodies) receptor 2 (AVPR2) mutant that is defective in trafficking to cell surface, can functionally be rescued.

  2. Conditional inactivation of Elf5 (show ELF5 Antibodies) in the developing collecting ducts results in a small but significant reduction in the expression levels of Aqp2 (show AQP2 Antibodies) and Avpr2 genes.

  3. Data show that cryptochrome Cry1 (show CRY1 Antibodies) and Cry2 (show CRY2 Antibodies) expression must be circadian and appropriately phased to support rhythms, and arginine vasopressin (AVP (show AVP Antibodies)) receptor signaling is required to impose circuit-level circadian function.

  4. In polycystic kidney disease, structural or functional loss of cilia leads to abnormal trafficking of AQP2 (show AQP2 Antibodies)/V2R leading to enhanced salt and water absorption.

  5. AVPR2 expression levels in the kidneys of male TALLYHO/JngJ mice, independent of diabetes disease state, were significantly reduced compared with those of B6 mice.

  6. V(2)R mRNA was expressed in medullary TAL (show TALDO1 Antibodies) (MTAL), macula densa, connecting tubule, and cortical and medullary collecting duct, and was weakly expressed in cortical TAL (show TALDO1 Antibodies) and distal convoluted tubule in rat, mouse, and human

  7. The data support roles for multiple vasopressin V2-receptor-dependent signaling pathways in the vasopressin (show AVP Antibodies) signaling network of collecting duct cells, involving several kinases not generally accepted to regulate collecting duct function.

  8. NF-kappaB (show NFKB1 Antibodies) activation is of importance for the downregulation of AQP2 (show AQP2 Antibodies) channel and vasopressin (show AVP Antibodies) V(2) receptor expression during sepsis. NF-kappaB (show NFKB1 Antibodies) inhibition ameliorates sepsis-induced acute renal failure.

  9. RNA interference methodology can be used successfully in vivo to significantly reduce functional expression of the V2R in the mouse kidney.

  10. Pax (show PXN Antibodies) transactivation domain-interacting protein is required for the urine concentration mechanism by modulating arginine vasopressin receptor 2 and AQP2 (show AQP2 Antibodies) expression in the inner medulla.

AVPR2 Antigen Profile

Antigen Summary

This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing.

Alternative names and synonyms associated with AVPR2

  • arginine vasopressin receptor 2 (AVPR2) antibody
  • vasopressin V2 receptor (AVPR2) antibody
  • arginine vasopressin receptor 2 (Avpr2) antibody
  • ADHR antibody
  • AVPR2 antibody
  • DI1 antibody
  • DIR antibody
  • DIR3 antibody
  • ND1 antibody
  • NDI antibody
  • V2R antibody
  • VPV2R antibody

Protein level used designations for AVPR2

vasopressin V2 receptor , arginine vasopressin receptor 2 , AVPR V2 , antidiuretic hormone receptor , renal-type arginine vasopressin receptor , V-2 lysine vasopressin receptor , V2R , arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) , nephrogenic diabetes insipidus , Vasopressin receptor V2

100528011 Ovis aries
697763 Macaca mulatta
100137253 Papio anubis
100328747 Oryctolagus cuniculus
100595937 Nomascus leucogenys
554 Homo sapiens
397462 Sus scrofa
281642 Bos taurus
12000 Mus musculus
25108 Rattus norvegicus
403804 Canis lupus familiaris
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