AVPR2 antibody (C-Term)

Catalog No. ABIN1492332

Product Details anti-AVPR2 Antibody

Target: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Binding Specificity: C-Term

Reactivity: Human, Monkey, Cow, Dog, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human AVPR2

Predicted Reactivity: Percent identity by BLAST analysis: Guinea pig (100%) Mouse (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from C-Terminus of human AVPR2 (P30518, NP_000045). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Marmoset, Guinea pig (100%), Mouse, Rat (92%), Galago, Bat, Rabbit, Horse (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 - 5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09% sodium azide, 2% sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-AVPR2 antibody (ABIN1492332)

Sakai, Yamazaki, Ishizawa, Tamura, Wang, Ueno, Hayama, Fujigaki, Shibata: "Upregulation of renal Na-K-2Cl cotransporter 2 in obese diabetes mellitus via a vasopressin receptor 2-dependent pathway." in: Biochemical and biophysical research communications, Vol. 524, Issue 3, pp. 710-715, (2020) (PubMed).

Target Details for AVPR2

Target: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Alternative Name: AVPR2 / V2R (AVPR2 Products)

Synonyms: AVPR2 antibody, ADHR antibody, DI1 antibody, DIR antibody, DIR3 antibody, NDI antibody, V2R antibody, ND1 antibody, VPV2R antibody, arginine vasopressin receptor 2 antibody, AVPR2 antibody, Avpr2 antibody

Background: Name/Gene ID: AVPR2
Subfamily: Vasopressin/oxytocin
Family: GPCR

Synonyms: AVPR2, ADHR, AVPR V2, Avp2r, Antidiuretic hormone receptor, DI1, DIR3, NDI, Vasopressin type 2 receptor, Vasopressin type II receptor, Vasopressin V2 receptor, V2 vasopressin receptor, Vasopressin receptor type 2, DIR, Type 2 vasopressin receptor, V2-renal V2R, V2R

Gene ID: 554

NCBI Accession: NP_000045

UniProt: P30518

Pathways: cAMP Metabolic Process