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Both FMRP (show FMR1 ELISA Kits) deficiency in Fmr1 (show FMR1 ELISA Kits)(I304N) mice and Fmr1 (show FMR1 ELISA Kits) knockdown impeded the axonal delivery of miR (show MLXIP ELISA Kits)-181d, Map1b (show MAP1B ELISA Kits), and Calm1 and reduced the protein levels of MAP1B (show MAP1B ELISA Kits) and calmodulin in axons.
The association of calcium-bound calmodulin (CaM) with DREAM is mediated by a short amphipathic amino acid sequence located between residues 29 and 44 on DREAM.
Calcium plays a role in regulating the expression and function of beta-adducin to sustain normal organization of the spectrin-based cytoskeleton and the differentiation properties in keratinocytes through the calmodulin/EGFR/cadherin signaling pathway.
Data suggest that Cys3602 in RyR2 (ryanodine receptor 2 (show RYR2 ELISA Kits)) plays important role in activation/termination of Ca2 (show CA2 ELISA Kits)+ release, but it is not essential for calmodulin regulation of RyR2 (show RYR2 ELISA Kits).
CaM plays an active role in shaping both the spatial and temporal aspects of calcineurin-mediated calcium signaling.
Calm1 signaling pathway is essential for the migration of mouse precerebellar neurons.
Ca(2+) binding to calmodulin induces major conformational changes in both IQ motifs and the post-IQ domain and increases flexibility of the myosin-1c tail.
Using mass spectrometry this study identified calmodulin as a calcium-dependent GluN2A (show GRIN2A ELISA Kits) binding partner.
new insights into the role of BTK (show BTK ELISA Kits), an important target for autoimmune diseases, in B cell activation (show BLNK ELISA Kits)
The relationships between the interaction of alphaCaMKII with CaM and the conformational change of alphaCaMKII, were investigated.
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).
, Calmodulin 1 (phosphorylase kinase, delta)