Browse our anti-RAMP2 (RAMP2) Antibodies

Full name:
anti-Receptor (G Protein-Coupled) Activity Modifying Protein 2 Antibodies (RAMP2)
On www.antibodies-online.com are 72 Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) Antibodies from 14 different suppliers available. Additionally we are shipping RAMP2 Proteins (9) and RAMP2 Kits (4) and many more products for this protein. A total of 86 RAMP2 products are currently listed.
Synonyms:
RAMP2, zgc:174936
list all antibodies Gene Name GeneID UniProt
RAMP2 54409 Q9WUP0
RAMP2 58966 Q9JHJ1
RAMP2 10266 O60895

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Most Popular Reactivities for anti-RAMP2 (RAMP2) Antibodies

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anti-Mouse (Murine) RAMP2 Antibodies:

anti-Rat (Rattus) RAMP2 Antibodies:

anti-Human RAMP2 Antibodies:

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Top referenced anti-RAMP2 Antibodies

  1. Human Polyclonal RAMP2 Primary Antibody for IF (p), IHC (p) - ABIN1386641 : Qiao, Wang, Wang, Zhao, Zhang, Han, Peng: Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction. in Nephrology (Carlton, Vic.) 2015 (PubMed)

More Antibodies against RAMP2 Interaction Partners

Mouse (Murine) Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) interaction partners

  1. The AM-RAMP2 system exerts crucial vasoprotective effects after vascular injury and could be a therapeutic target for the treatment of vascular diseases.

  2. Results provide in vivo evidence of a role for RAMP2 in placental development distinct from the RAMP2-calcitonin receptor-like receptor (show CALCRL Antibodies)/adrenomedullin (show ADM Antibodies) signaling paradigm; decreases Pthr1 (show PTH1R Antibodies) expression and causes a blunted response to systemic parathyroid hormone (show PTH Antibodies); and identify additional pathways underlying the endocrine and fertility defects of the previously characterized Ramp2 heterozygous adult females.

  3. the Adrenomedullin (show ADM Antibodies)-RAMP2 system regulates vascular integrity, whereas RAMP2 deletion promotes vascular permeability

  4. RAMP2 is essential for early vascular development and knockout-mice die in utero.

  5. These results indicate the AM-RAMP2 system works to protect nerve cells from both acute and chronic cerebral ischemia by maintaining cerebral blood flow suppressing oxidative stress, and in the case of chronic ischemia, enhancing capillary growth.

  6. The AM-RAMP2 system is a key determinant of vascular integrity and homeostasis from prenatal stages through adulthood.

  7. These data demonstrate that the adrenomedullin (show ADM Antibodies)-RAMP2 system is essential for cardiac metabolism and homeostasis.

  8. Data show that mechanical ventilation reduced the expression of receptor activity-modifying protein RAMP3 (show RAMP3 Antibodies), but not of intermedin (IMD (show ADM2 Antibodies)), calcitonin receptor-like receptor (CRLR (show CALCRL Antibodies)), and RAMP1 (show RAMP1 Antibodies) and RAMP2.

  9. Adrenomedullin (show ADM Antibodies)-RAMP2 system is the potential target for the induction of liver sinusoidal endothelial cells.

  10. this work reveals an essential role for RAMP2 in endocrine physiology and provides the first in vivo evidence for a physiological role of RAMP2 beyond that of AM/CLR (show CALCR Antibodies) signaling

Human Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) interaction partners

  1. This work suggests that RAMP2 may modify the agonist activity and trafficking of the GCGR (show GCGR Antibodies), with potential relevance to production of new peptide analogs with selective agonist activities.

  2. Data suggest that a single GlcNAc residue at CTR (show CALCR Antibodies) N130 (asparagine 130) is responsible for enhanced affinity of calcitonin (show CALCA Antibodies) for CTR (show CALCR Antibodies) ECD (show SHFM1 Antibodies); the same appears to apply for enhanced affinity of amylin (show IAPP Antibodies) for RAMP2-CTR (show CALCR Antibodies) ECD (show SHFM1 Antibodies). [GlcNAc = N-acetylglucosamine; CTR (show CALCR Antibodies) = calcitonin receptor (show CALCR Antibodies); ECD (show SHFM1 Antibodies) = extracellular domain; RAMP2 = receptor (calcitonin) activity modifying protein 2].

  3. interaction of RAMP2 or RAMP3 (show RAMP3 Antibodies) with CLR (show DCLK3 Antibodies) induces conformational variation in the juxtamembrane region, yielding distinct binding pockets, probably via an allosteric mechanism.

  4. This study reveals the glucagon receptor (show GCGR Antibodies) as a previously unidentified target for GLP-1 receptor (show GLP1R Antibodies) agonists and highlights a role for RAMP2 in regulating its pharmacology.

  5. Data suggest that ligand binding of a G protein-coupled receptor (GPCR (show TAS1R3 Antibodies)) may inform drug development targeting calcitonin receptor-like receptor (CLR (show CALCRL Antibodies)):receptor activity-modifying proteins RAMP1 (show RAMP1 Antibodies)/2 complexes.

  6. the AM system is widely expressed in human thymus from newborns; both AM1 receptor components CLR (show DCLK3 Antibodies) and RAMP2, but not RAMP3 (show RAMP3 Antibodies), are not associated with the plasma membrane of TECs and thymocytes but are located intracellularly, notably in the nucleus

  7. Adrenomedullin (show ADM Antibodies)-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection.

  8. Data suggest isoforms of RAMP modulate accessibility of peptides to residues situated on CALCRL (calcitonin receptor-like receptor (show CALCRL Antibodies)) N-terminal domain; RAMP3 (show RAMP3 Antibodies)/RAMP2/RAMP1 (show RAMP1 Antibodies) appear to alter accessibility of specific residues at CALCRL (show CALCRL Antibodies)-RAMP interface.

  9. RAMP2 gene expression increases with gestational age development in the fetal lung.

  10. The CRLR (show CALCRL Antibodies)-RAMP2 interactions were confirmed for the full-length proteins on the cell surface by site-specific photo-crosslinking.

Cow (Bovine) Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) interaction partners

  1. Data indicate that adrenomedullin (show ADM Antibodies) mRNA and protein signal were only found in trophoblast binucleate cells (BNCs), whereas those of CRLR (show CALCRL Antibodies), RAMP2 and RAMP3 (show RAMP3 Antibodies) were detected in cotyledonary villous and caruncular epithelial cells.

RAMP2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

Alternative names and synonyms associated with RAMP2

  • receptor (G protein-coupled) activity modifying protein 2 (RAMP2) antibody
  • receptor (G protein-coupled) activity modifying protein 2 (ramp2) antibody
  • receptor (G protein-coupled) activity modifying protein 2 (LOC100224587) antibody
  • receptor (calcitonin) activity modifying protein 2 (Ramp2) antibody
  • receptor (G protein-coupled) activity modifying protein 2 (Ramp2) antibody
  • RAMP2 antibody
  • zgc:174936 antibody

Protein level used designations for RAMP2

receptor (calcitonin) activity modifying protein 2 , receptor activity modifying protein 2 , receptor activity-modifying protein 2 , receptor (G protein-coupled) activity modifying protein 2 , receptor activity modifying protein 2 isoform , CRLR activity-modifying protein 2 , calcitonin receptor-like receptor activity modifying protein 2 , calcitonin-receptor-like receptor activity-modifying protein 2 , receptor-activity-modifying protein 2

GENE ID SPECIES
420022 Gallus gallus
480515 Canis lupus familiaris
566313 Danio rerio
707718 Macaca mulatta
100224587 Taeniopygia guttata
54409 Mus musculus
100135611 Cavia porcellus
58966 Rattus norvegicus
10266 Homo sapiens
454698 Pan troglodytes
397155 Sus scrofa
504230 Bos taurus
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