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RAN Antibodies

(RAN, Member RAS Oncogene Family (RAN))
RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease. [provided by RefSeq, Jul 2008].
anti-RAN, Member RAS Oncogene Family (RAN) (AA 1-216) antibody anti-RAN, Member RAS Oncogene Family (RAN) (AA 1-216) antibody anti-RAN, Member RAS Oncogene Family (RAN) (AA 1-216) antibody (ABIN5542382)

RAN Reactivity: Human, Mouse, Rat, Monkey ELISA, FACS, ICC, IHC, WB Host: Mouse Monoclonal 8D1A6 unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 2-216) antibody anti-RAN, Member RAS Oncogene Family (RAN) (AA 2-216) antibody anti-RAN, Member RAS Oncogene Family (RAN) (AA 2-216) antibody (ABIN5518950)

RAN Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-RAN, Member RAS Oncogene Family (RAN) (AA 12-39) antibody anti-RAN, Member RAS Oncogene Family (RAN) (AA 12-39) antibody anti-RAN, Member RAS Oncogene Family (RAN) (AA 12-39) antibody (ABIN3032431)

RAN Reactivity: Human, Mouse FACS, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

RAN Antibodies by Grade

Find RAN Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

RAN Antibodies by Reactivity

Find RAN Antibodies for a variety of species such as anti-Human RAN, anti-Rat RAN, anti-Mouse RAN. The species listed below are among those available. Click on a link to go to the corresponding products.

RAN Antibodies by Application

Find RAN Antibodies validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

RAN Antibodies by Host

Find RAN Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

RAN Antibodies by Binding Specificity

Find RAN Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

RAN Antibodies by Clonality

Find available monoclonal or polyclonal RAN Antibodies. Click on a link to go to the corresponding products.

RAN Antibodies by Clone

Find RAN Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

RAN Antibodies by Conjugate

Find RAN Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular RAN Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application FACS, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3032430
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
  • (4)
Cat. No. ABIN3021203
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, IHC, ELISA, WB
Validations
  • (4)
Cat. No. ABIN2496204
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IF, IHC, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN467626
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN390647
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN185256
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN571291
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1533388
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN6264629
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN652226
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN562575
Quantity 50 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Monkey, Mouse, Rat
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN2705170
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN2496205
Quantity 400 μL
Datasheet Datasheet
Reactivity Hamster, Human, Mouse, Rat
Application IF, IP, WB
Validations
  • (2)
Cat. No. ABIN1449197
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (1)
Cat. No. ABIN3186685
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our RAN Antibodies

Zhang, Yang, Cao, Xu, Li, Chen, Gao, Xin, Zhou, Zhou, Yang, Sheng, Zeng: "MiR-203 suppresses tumor growth and invasion and down-regulates MiR-21 expression through repressing Ran in esophageal cancer." in: Cancer letters, Vol. 342, Issue 1, pp. 121-9, (2013) (PubMed).

Xia, Dohi, Martin, Raskett, Liu, Altieri: "Essential role of the small GTPase Ran in postnatal pancreatic islet development." in: PLoS ONE, Vol. 6, Issue 11, pp. e27879, (2011) (PubMed).

Ly, Wang, Pereira, Rojas, Peng, Feng, Cerione, Wilson: "Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5815-26, (2010) (PubMed).

Simula, Cannizzaro, Canzonieri, Pavan, Maiero, Toffoli, De Re: "PPAR signaling pathway and cancer-related proteins are involved in celiac disease-associated tissue damage." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 5-6, pp. 199-209, (2010) (PubMed).

Nilsen, Rosendal, Sørensen, Wesche, Olsnes, Wiedłocha: "A nuclear export sequence located on a beta-strand in fibroblast growth factor-1." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26245-56, (2007) (PubMed).

Ramos, Rafikova, Melikov, Chernomordik: "Transmembrane proteins are not required for early stages of nuclear envelope assembly." in: The Biochemical journal, Vol. 400, Issue 3, pp. 393-400, (2006) (PubMed).

Nemergut, Lindsay, Brownawell, Macara: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, (2002) (PubMed).

Schwoebel, Ho, Moore: "The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 963-74, (2002) (PubMed).

Faleiro, Lazebnik: "Caspases disrupt the nuclear-cytoplasmic barrier." in: The Journal of cell biology, Vol. 151, Issue 5, pp. 951-9, (2000) (PubMed).

Iborra, Jackson, Cook: "The path of RNA through nuclear pores: apparent entry from the sides into specialized pores." in: Journal of cell science, Vol. 113 Pt 2, pp. 291-302, (2000) (PubMed).

Aliases for RAN Antibodies

RAN, member RAS oncogene family (RAN) Antibodies
RAN, member RAS oncogene family (Ran) Antibodies
RAN, member RAS oncogene family S homeolog (ran.S) Antibodies
RAN, member RAS oncogene family (ran) Antibodies
CG1404 gene product from transcript CG1404-RC (Ran) Antibodies
AAF30287 Antibodies
ARA24 Antibodies
ara24 Antibodies
CG1404 Antibodies
Dmel\CG1404 Antibodies
dran Antibodies
fc16b04 Antibodies
Gsp1 Antibodies
gsp1 Antibodies
l(1)G0075 Antibodies
ran Antibodies
RAN Antibodies
Ran Antibodies
ran-1 Antibodies
ran10A Antibodies
RANP1 Antibodies
TC4 Antibodies
tc4 Antibodies
wu:fc16b04 Antibodies
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