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Human TIMP2 ELISA Kit for Sandwich ELISA - ABIN625100
Chon, Kim, Ahn: Transient elastography in real practice: a time for action? in Journal of gastroenterology and hepatology 2012
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Human TIMP2 ELISA Kit for Sandwich ELISA - ABIN411359
Kim, Lee, Choi, Yoo, Yang: Implication of MMP-9 and urokinase plasminogen activator (uPA) in the activation of pro-matrix metalloproteinase (MMP)-13. in Rheumatology international 2012
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Human TIMP2 ELISA Kit for Sandwich ELISA - ABIN414925
Hu, Cui, Yang, Wang, Hu, Li, Zeng: Bone morphogenetic protein-2: a potential regulator in scleral remodeling. in Molecular vision 2008
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Mouse (Murine) TIMP2 ELISA Kit for Sandwich ELISA - ABIN415607
Kim, Shin, Park, Hong, Shin, Kim, Kwon, Park: Oral administration of 3,3'-diindolylmethane inhibits lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice. in The Journal of nutrition 2009
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Mouse (Murine) TIMP2 ELISA Kit for Sandwich ELISA - ABIN1889329
De Clerck, Szpirer, Aly, Cassiman, Eeckhout, Rousseau: The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. in Genomics 1992
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Rat (Rattus) TIMP2 ELISA Kit for Sandwich ELISA - ABIN1889442
Seo, Li, Guedez, Wingfield, Diaz, Salloum, Wei, Stetler-Stevenson: TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. in Cell 2003
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Rat (Rattus) TIMP2 ELISA Kit for Sandwich ELISA - ABIN416333
Michalski, Pelz, Weise, Kacza, Boltze, Grosche, Kamprad, Schneider, Hobohm, Härtig: Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke. in Experimental & translational stroke medicine 2011
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Mouse (Murine) TIMP2 ELISA Kit for Sandwich ELISA - ABIN625181
Cuaz-Pérolin, Jguirim, Larigauderie, Jlassi, Furman, Moreau, Chapman, Fruchart, Slimane, Mezdour, Rouis: Apolipoprotein E knockout mice over-expressing human tissue inhibitor of metalloproteinase 1 are protected against aneurysm formation but not against atherosclerotic plaque development. in Journal of vascular research 2006
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Horse (Equine) TIMP2 ELISA Kit for Sandwich ELISA - ABIN416675
Barton, Shety, Bondzio, Einspanier, Gehlen: Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy in combination with environmental dust reduction in equine recurrent airway obstruction. in BMC veterinary research 2016
Pig (Porcine) TIMP2 ELISA Kit for Sandwich ELISA - ABIN415894
Witt, Glage, Schulz, Lichtinghagen, Simann, Pape, Sümpelmann: Impact of 6% hydroxyethyl starch 130/0.42 and 4% gelatin on renal function in a pediatric animal model. in Paediatric anaesthesia 2014
Suggest that IL-6 (show IL6 ELISA Kits) could promote the invasiveness of breast cancer cells by inducing secretion of TIMP-1 (show TIMP1 ELISA Kits) and -2, causing a disturbance in TIMP/MMP balance.
High TIMP2 expression is associated with acute kidney injury.
expression of TIMP2 was inversely associated with miR (show MLXIP ELISA Kits)-106a in nodule tissues. Apoptotic body was also seen under electron microscope accompanied by silencing of miR (show MLXIP ELISA Kits)-106a. Together, this data indicated that miR (show MLXIP ELISA Kits)-106a may act as an oncogene (show RAB1A ELISA Kits) and contribute to gastric cancer development.
Data show that the mean values for TIMP1 (show TIMP1 ELISA Kits), TIMP2 and MMP2 (show MMP2 ELISA Kits) were lower in survivors, MMP9 (show MMP9 ELISA Kits) was higher in survivors.
Urine [TIMP-2]*[IGFBP7 (show IGFBP7 ELISA Kits)] is a promising candidate for early detection of AKI, especially in ruling-out AKI
We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7 (show MMP7 ELISA Kits), MMP-10 (show MMP10 ELISA Kits) and TIMP-1 (show TIMP1 ELISA Kits) correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the disease. MMP-10 (show MMP10 ELISA Kits), MMP-7 (show MMP7 ELISA Kits), TIMP-1 (show TIMP1 ELISA Kits), TIMP-2 were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.
At hospital admission, all viral gastroenteritis (GE) patients viral gastroenteritis (GE) patients demonstrated increased MMP-9 (show MMP9 ELISA Kits) and decreased MMP-2 (show MMP2 ELISA Kits) and TIMP-2 serum levels; kinetics of serum MMP-2 (show MMP2 ELISA Kits), MMP-9 (show MMP9 ELISA Kits), and TIMP-2 levels were similar among the viral GE patients but distinct from bacterial enteritis patients; involvement of MMPs and TIMPs in the pathophysiology of gastrointestinal symptoms likely varies depending on the
Meta-analysis indicated that urinary [TIMP-2].[IGFBP7 (show IGFBP7 ELISA Kits)] may be a reliable biomarker for the early detection of acute kidney injury in adults.
Results show that resistant hypertension was associated with higher TIMP-2 levels and low MMP-2 (show MMP2 ELISA Kits)/TIMP-2 ratio, suggesting that these regulators of ECM (show MMRN1 ELISA Kits) remodeling play a key role in blood pressure control in this high-risk subset of hypertensive individuals.
Data indicate the involvement of PKC-alpha (show PKCa ELISA Kits) in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB (show NFKB1 ELISA Kits)-MT1-MMP (show MMP14 ELISA Kits)-dependent and -independent pathway.
A differential pattern of matrix metalloproteinase-2 (show MMP2 ELISA Kits) and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.
MMP-14 (show MMP14 ELISA Kits), MMP-2 (show MMP2 ELISA Kits) and TIMP-2 are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.
Results describe distinct changes in expression of MMP2 (show MMP2 ELISA Kits), MMP14 (show MMP14 ELISA Kits), and the metallopeptidase (show ECEL1 ELISA Kits) inhibitor TIMP2 between different phases of the estrous cycle indicating an endocrine regulation.
Production of TIMP-1 (show TIMP1 ELISA Kits) was augmented by IL-1alpha, TNFalpha (show TNF ELISA Kits), and hepatocyte growth factor (show HGF ELISA Kits) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 mRNA was not affected by any treatments.
the different temporal expression patterns of TIMP-1 (show TIMP1 ELISA Kits) and TIMP-2 suggest that TIMP-1 (show TIMP1 ELISA Kits) may be important for luteal formation and development, while TIMP-2 may play significant roles during luteal development and maintenance
Identification, purification and partial characterization of timp-2 in bovine pulmonary artery smooth muscle
Results describe the isolation of matrix metalloproteinase 2 (MMP-2 (show MMP2 ELISA Kits)) from the MMP-2 (show MMP2 ELISA Kits)/tissue inhibitor of metalloproteinase 2 (TIMP-2) complex, and the characterization of both isolated MMP-2 (show MMP2 ELISA Kits) and the complex itself.
oxidants inactivate TIMP-2, and the resulting activation of MMP-2 (show MMP2 ELISA Kits) subsequently inhibits Na+ dependent Ca2 (show CA2 ELISA Kits)+ uptake in the microsomes
TIMP-2 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.
The pathology of laminitis is associated with increased and lowered transcription of MMP-14 (show MMP14 ELISA Kits) and TIMP-2, respectively.
the protein expression levels of TIMP-2 and PBEF (show NAMPT ELISA Kits) in cloned placentae, were examined.
demonstrate that TIMP-2 plays a greater protective role than TIMP-1 (show TIMP1 ELISA Kits) during the pathogenesis of atherosclerosis
Further investigation of MMP2 (show MMP2 ELISA Kits) inhibitors of TIMP2/TIMP4 (show TIMP4 ELISA Kits) showed an upregulated TIMP2 expression, but not TIMP4 (show TIMP4 ELISA Kits). low-dose pre-radiation attenuates the skin inflammation and ROS (show ROS1 ELISA Kits) production induced by medium-dose UV radiation
TIMP2 and TIMP3 (show TIMP3 ELISA Kits) play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function
Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (show MAPK14 ELISA Kits) signaling pathway.
High TIMP2 expression is associated with liver fibrosis.
TIMP2 promotes kidney injury through metalloproteinase (MMP)2 (show MMP2 ELISA Kits) activation
Gene expression of Mmp-12 (show MMP12 ELISA Kits) and Mmp-13 (show MMP13 ELISA Kits), and Timp-1 (show TIMP1 ELISA Kits) was strongly upregulated at all time points in RD compared with controls. Timp-2, Mmp-2 (show MMP2 ELISA Kits), and Mmp-9 (show MMP9 ELISA Kits) expression was modest.
Data indicate a significantly increased expression of type I collagen, TIMP-2, TGF-beta (show TGFB1 ELISA Kits), PAI-1 (show SERPINE1 ELISA Kits) and RAGE (show AGER ELISA Kits) in diabetic db/db (show LEPR ELISA Kits) cells.
This study suggests that miR-17 participates in the regulation of cardiac matrix remodeling and provides a novel therapeutic approach using miR-17 inhibitors to prevent remodeling and heart failure after MI.
To further study the function of TIMP-2 in development, we utilized zebrafish as an experimental model system
membrane-type 1 metalloproteinase, gelatinase A (show MMP2 ELISA Kits) , and tissue inhibitor 2 of metalloproteinases mRNA transcripts were expressed in the blastema
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
, metalloproteinase inhibitor 2
, tissue inhibitor of metalloproteinase 2
, tissue inhibitor of metalloproteinases 2
, collagenase inhibitor
, tissue inhibitor of mettaloproteinase 2
, tissue inhibitor of metalloproteinase-2
, tissue inhibitor of matrix metalloproteinase-2
, metalloproteinase inhibitor TIMP-2