Browse our VIPR2 Proteins (VIPR2)

Full name:
Vasoactive Intestinal Peptide Receptor 2 Proteins (VIPR2)
On are 8 Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Proteins from 5 different suppliers available. Additionally we are shipping VIPR2 Antibodies (84) and VIPR2 Kits (9) and many more products for this protein. A total of 104 VIPR2 products are currently listed.
C16DUPq36.3, DUP7q36.3, LOC100136266, LOC100224359, LOC100229999, pacap, PACAP-R-3, PACAP-R3, VIP-R-2, Vip2, VIPR2, VPAC2, vpac2-r, VPAC2R, VPCAP2R
list all proteins Gene Name GeneID UniProt
VIPR2 7434 P41587
Mouse VIPR2 VIPR2 22355 P41588
Rat VIPR2 VIPR2 29555 P35000

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VIPR2 Proteins (VIPR2) by Origin

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More Proteins for VIPR2 Interaction Partners

Zebrafish Vasoactive Intestinal Peptide Receptor 2 (VIPR2) interaction partners

  1. Study found a protective effect of PACAP-38 (show ADCYAP1 Proteins) on oxidative stress damage in zebrafish hair cells, suggesting PACAP-38 (show ADCYAP1 Proteins) ability to prevent hair cells from apoptosis. PACAP-38 (show ADCYAP1 Proteins) treatment decreased the cleaved caspase-3 (show CASP3 Proteins) level in the hair cells, but somewhat unexpectedly had no influence on p-38 MAPK (show MAPK1 Proteins) pathway. PACAP-38 (show ADCYAP1 Proteins) treatment also rescued H2O2-induced reduction in movement.

  2. PACAP might play dual roles in regulating follicle growth and maturation through different receptors located in different compartments.

  3. These results suggest that, in fish, PACAP and PAC1-R may play a role in brain development.

  4. The temporal and spatial expression pattern of the ghrh-pacap1 (show ADCYAP1 Proteins) transcript suggests that these hormones may modulate patterning during development.

  5. zfPACAP38-2 is a potential ovarian factor that mediates gonadotropin actions in paracrine/autocrine manners, and its functional roles are likely, to some extent, related to the ovarian activin/follistatin (show FST Proteins) system.

Pig (Porcine) Vasoactive Intestinal Peptide Receptor 2 (VIPR2) interaction partners

  1. Splice variants of pVPAC1-R are predominantly expressed in all tissues instead of the transcript encoding the full-length receptor, hinting that pVPAC2-R may play more important roles than pVPAC1-R in mediating VIP (show Vip Proteins) and PACAP (show ADCYAP1 Proteins) actions.

Human Vasoactive Intestinal Peptide Receptor 2 (VIPR2) interaction partners

  1. In vitro-polarized macrophages by GM-CSF (show CSF2 Proteins) (GM-MO), with a proinflammatory profile, expressed higher levels of VIP (show Vip Proteins) receptors, vasoactive intestinal polypeptide (show Vip Proteins) receptors 1 and 2 (VPAC1 (show VIPR1 Proteins) and VPAC2, respectively), than macrophages polarized by M-CSF (show CSF1 Proteins) (M-MO) with anti-inflammatory activities. RA synovial macrophages, according to their GM-CSF (show CSF2 Proteins)-like polarization state, expressed both VPAC1 (show VIPR1 Proteins) and VPAC2.

  2. Lower CpG methylation of VIPR2 in the saliva (show RAG1AP1 Proteins) of children with ADHD.

  3. The results reveal that more severe inflammation, based on high levels of IL-6 (show IL6 Proteins), is associated with lower expression of VPAC1 (show VIPR1 Proteins) and, conversely, with increased expression of VPAC2.

  4. CD4 (show CD4 Proteins)+ T cells in HIV infection show increased levels of expression of VPAC2

  5. This study suggest that carriers of microduplication genotypes of VIPR2 are predisposed to SCZ in Han Chinese.

  6. Monocytes from Sjogren's syndrome patients display increased vasoactive intestinal peptide receptor 2 expression and impaired apoptotic cell phagocytosis.

  7. Data indicate that VIP (show Vip Proteins) and PACAP (show ADCYAP1 Proteins) increased macrophage resistance to HIV-1 replication by inducing the synthesis of beta-chemokines CCL3 (show CCL3 Proteins) and CCL5 (show CCL5 Proteins) and IL-10 (show IL10 Proteins) following preferential activation of the receptors VPAC2 and PAC1 (show ADCYAP1R1 Proteins).

  8. This is the first study to suggest a role of VIPR2 in the genetic susceptibility to high myopia. EGR1 (show EGR1 Proteins), JUN (show JUN Proteins), FOS and VIP (show Vip Proteins) are unlikely to be important in predisposing humans to high myopia.

  9. Genetic testing for VIPR2-LCR-associated inversions should be performed on available cohorts of psychiatric patients to evaluate their potential pathogenic role

  10. Conclude that VPAC2/PAC1 (show ADCYAP1R1 Proteins) receptors require NO in series to effect cutaneous active vasodilation during heat stress in humans.

Mouse (Murine) Vasoactive Intestinal Peptide Receptor 2 (VIPR2) interaction partners

  1. Results demonstrate critical protective roles for PACAP (show ADCYAP1 Proteins) and the VPAC2 receptor against autoimmunity, promoting the expansion and maintenance of the Treg pool.

  2. The results suggest that caveolin-1 (show CAV1 Proteins) plays an important role in VPAC2 receptor internalization and desensitization.

  3. Cumulus cells express PACAP (show ADCYAP1 Proteins) and its receptors PAC1-R and VPAC2-R.

  4. VPAC2R mRNA expression showed a nonsignificant tendency to increase on day 7 after ischemia induced by bilateral common carotid artery occlusion.

  5. The loss of adrenal clock gene rhythm in the VPAC2 receptor knockout mice after transfer into constant darkness was accompanied by disappearance of rhythmicity in Star mRNA expression and serum corticosterone concentration.

  6. Cyclophosphamide-induced cystitis significantly decreased VPAC2 receptor expression in the urothelium & detrusor of both WT and NGF-OE mice

  7. The circadian clock, not ambient light level, regulates Vipr2 protein localization, since VAPC2R plays a role in signaling at all times of day.

  8. Data support the notion that both VPAC1 (show VIPR1 Proteins) and VPAC2 receptors are dynamically regulated by Ikaros (show IKZF1 Proteins), a master transcriptional regulator for thymocyte differentiation, during early thymic development.

  9. results support that decline in VIP (show Vip Proteins)/VPAC local levels may influence survival/apoptosis intracellular set point in NOD acinar cells and their clearance, contributing to gland homeostasis loss in a model of Sjogren's syndrome

  10. Toll-like receptor 4 (show TLR4 Proteins) and 5 stimulation differentially regulates vasoactive intestinal peptide (show Vip Proteins) type 2 receptor in macrophages

VIPR2 Protein Profile

Protein Summary

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase.

Alternative names and synonyms associated with VIPR2

  • vasoactive intestinal peptide receptor 2 (VIPR2)
  • vasoactive intestinal polypeptide receptor type 2 (LOC100136266)
  • vasoactive intestinal peptide receptor 2 (LOC100224359)
  • vasoactive intestinal peptide receptor 2 (vipr2)
  • vasoactive intestinal peptide receptor 2 (LOC100229999)
  • vasoactive intestinal peptide receptor 2 (Vipr2)
  • C16DUPq36.3 protein
  • DUP7q36.3 protein
  • LOC100136266 protein
  • LOC100224359 protein
  • LOC100229999 protein
  • pacap protein
  • PACAP-R-3 protein
  • PACAP-R3 protein
  • VIP-R-2 protein
  • Vip2 protein
  • VIPR2 protein
  • VPAC2 protein
  • vpac2-r protein
  • VPAC2R protein
  • VPCAP2R protein

Protein level used designations for VIPR2

vasoactive intestinal peptide receptor 2 , vasoactive intestinal polypeptide receptor type 2 , PHI-R , PHIR , histidine-isoleucine receptor , pituitary adenylate cyclase-activating peptide , vasoactive intestinal polypeptide receptor 2 , vasoactive intestingal polypeptide receptor type 2 , VPAC2 receptor , VIP-specific receptor , gastric VPAC2 receptor , vasoactive intestinal polypeptide receptor 2-like , vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 2 , PACAP type III receptor , VIP and PACAP receptor 2 , helodermin-preferring VIP receptor , pituitary adenylate cyclase-activating polypeptide type III receptor , PACAP-R-3 , PACAP-R3 , VIP receptor subtype 2 , VIP-R-2 , vasopressive intestinal peptide receptor 2

611663 Canis lupus familiaris
706344 Macaca mulatta
100009382 Oryctolagus cuniculus
100136266 Oncorhynchus mykiss
100224359 Taeniopygia guttata
81886 Danio rerio
420453 Gallus gallus
100021265 Monodelphis domestica
100145780 Xenopus (Silurana) tropicalis
100229999 Taeniopygia guttata
100379253 Cavia porcellus
100385837 Callithrix jacchus
100499553 Sus scrofa
100080907 Ornithorhynchus anatinus
100484201 Ailuropoda melanoleuca
100500781 Ovis aries
100615624 Pan troglodytes
7434 Homo sapiens
22355 Mus musculus
29555 Rattus norvegicus
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