Browse our Cadherin 8 Proteins (CDH8)

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Cadherin 8 Proteins (CDH8)
On are 15 Cadherin 8 (CDH8) Proteins from 6 different suppliers available. Additionally we are shipping Cadherin 8 Antibodies (46) and many more products for this protein. A total of 71 Cadherin 8 products are currently listed.
AI851472, cad8, cadherin-8, Nbla04261
list all proteins Gene Name GeneID UniProt
CDH8 12564 P97291
CDH8 84408  
CDH8 1006 P55286

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Cadherin 8 Proteins (CDH8) by Origin

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Top referenced Cadherin 8 Proteins

  1. Rat (Rattus) Cadherin 8 Protein expressed in Human Cells - ABIN2009415 : Kido, Obata, Tanihara, Rochelle, Seldin, Taketani, Suzuki: Molecular properties and chromosomal location of cadherin-8. in Genomics 1998 (PubMed)
    Show all 4 references for 2009415

  2. Human Cadherin 8 Protein expressed in Human Cells - ABIN2002165 : Tanihara, Sano, Heimark, St John, Suzuki: Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin. in Cell adhesion and communication 1995 (PubMed)
    Show all 3 references for 2002165

More Proteins for Cadherin 8 Interaction Partners

Mouse (Murine) Cadherin 8 (CDH8) interaction partners

  1. Results indicate that Cdh8 delineates developing corticostriatal circuits where it is a strong candidate for regulating the generation of normal cortical projections, neuronal morphology, and corticostriatal synapses

  2. Study shows that bipolar cells BC2s and BC5s deliver visual input to neurons that compute direction of motion and demonstrate that Cdh8 and Cdh9 (show CDH9 Proteins) are required for assembly of the circuit.

  3. These results demonstrate that cad8 is essential for establishing the physiological coupling between cold-sensitive sensory neurons and their target DH neurons.

  4. Results describe individual monomer and dimer states and the monomer-dimer equilibrium of the mouse Type II cadherin-8 EC1 domain.

Human Cadherin 8 (CDH8) interaction partners

  1. Results show that promoter hypermethylation of ADCY8 (show ADCY8 Proteins), CDH8, and ZNF582 (show ZNF582 Proteins) are correlated with high-grade squamous intraepithelial lesion.

  2. cadherin 8, a type II neuronal cadherin, is expressed in cyst epithelia both in vivo and in vitro; data suggest that ectopic expression of cadherin 8 in renal epithelial cells is sufficient to cause the morphogenic pattern of cyst formation

  3. Rare familial 16q21 microdeletions and expression analysis implicate CDH8 in susceptibility to autism and learning disabilities.

  4. cadherin-8 may be involved in both kidney morphogenesis as well as tumorigenesis in some types of renal cell carcinoma (show MOK Proteins)

Cadherin 8 (CDH8) Protein Profile

Protein Summary

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

Alternative names and synonyms associated with Cadherin 8 (CDH8)

  • cadherin 8 (Cdh8)
  • cadherin 8, type 2 (CDH8)
  • AI851472 protein
  • cad8 protein
  • cadherin-8 protein
  • Nbla04261 protein

Protein level used designations for Cadherin 8 Proteins (CDH8)

cadherin-8 , cadherin 8, type 2 preproprotein

12564 Mus musculus
84408 Rattus norvegicus
427553 Gallus gallus
1006 Homo sapiens
521039 Bos taurus
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