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Browse our Claudin 19 Proteins (CLDN19)

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Claudin 19 Proteins (CLDN19)
On are 6 Claudin 19 (CLDN19) Proteins from 3 different suppliers available. Additionally we are shipping Claudin 19 Antibodies (36) and Claudin 19 Kits (12) and many more products for this protein. A total of 58 Claudin 19 products are currently listed.
claudin-19, HOMG5, zgc:112141
list all proteins Gene Name GeneID UniProt
CLDN19 149461 Q8N6F1
Rat CLDN19 CLDN19 298487 Q5QT56
CLDN19 242653 Q9ET38

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Claudin 19 Proteins (CLDN19) by Origin

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More Proteins for Claudin 19 Interaction Partners

Human Claudin 19 (CLDN19) interaction partners

  1. permeability barriers and affected cell morphology, proliferation, migration, AKT (show AKT1 Proteins) signaling, and gene expression. When claudins are exogenously expressed, ARPE-19 more closely model native RPE (show RPE Proteins).

  2. CLDN19 genetic mutation is responsible for familial magnesium deficiency with hypercalciuria and nephrocalcinosis.

  3. analysis of a novel mutation c.241C>T in exon 2 of CLDN19 in a Chinese patient

  4. Claudin-19, the most abundant claudin in myelin, exhibited no binding to ZO2 (show TJP2 Proteins) protein.

  5. patients with CLDN19 mutations have a high risk of progression to chronic renal disease

  6. Case Reports: novel CLDN19 mutation in familial hypomagnesemia with hypercalciuria and nephrocalcinosis.

  7. The risk of end-stage renal disease in patients with CLDN19 mutations was two times the risk of patients with CLDN16 (show CLDN16 Proteins) mutations. Ocular abnormalities were observed only in patients with CLDN19 mutations.

  8. In a patient with consanguineous parents, history of disturbed organization and development of the retina, a diagnosis of Familial hypomagnesemia with hypercalciuria and nephrocalcinosis caused by claudin-19 mutation should be considered.

  9. Ocular manifestations and exercise intolerance mimicking mild to moderate periodic paralysis are two symptoms that may occur in patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis and may indicate CLDN19 mutations.

  10. The identification of CLDN19 mutations in patients with chronic renal failure and severe visual impairment supports the fundamental role of claudin-19 for normal renal tubular function and undisturbed organization and development of the retina.

Mouse (Murine) Claudin 19 (CLDN19) interaction partners

  1. this study presents the structure of mammalian claudin-19 in complex with C-CPE (show CPE Proteins) at 3.7 A resolution.

  2. Sp1 (show SP1 Proteins) site is crucial for Cldn19 gene expression in kidney cells.

  3. Claudin-16 (show CLDN16 Proteins) and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium.

Claudin 19 (CLDN19) Protein Profile

Protein Summary

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with Claudin 19 (CLDN19)

  • claudin 19 (cldn19)
  • claudin 19 (CLDN19)
  • claudin 19 (LOC100357396)
  • claudin 19 (Cldn19)
  • claudin-19 protein
  • HOMG5 protein
  • zgc:112141 protein

Protein level used designations for Claudin 19 Proteins (CLDN19)

claudin-19 , claudin 19

496231 Xenopus laevis
550431 Danio rerio
697807 Macaca mulatta
747192 Pan troglodytes
100032684 Monodelphis domestica
100053591 Equus caballus
100357396 Oryctolagus cuniculus
149461 Homo sapiens
298487 Rattus norvegicus
607005 Canis lupus familiaris
100294682 Sus scrofa
513034 Bos taurus
242653 Mus musculus
101102362 Ovis aries
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