Browse our F2RL2 Proteins (F2RL2)

Full name:
Coagulation Factor II (thrombin) Receptor-Like 2 Proteins (F2RL2)
On www.antibodies-online.com are 3 Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2) Proteins from 2 different suppliers available. Additionally we are shipping F2RL2 Antibodies (41) and F2RL2 Kits (13) and many more products for this protein. A total of 60 F2RL2 products are currently listed.
Synonyms:
ASIP, Baz, F730031A08, PAR-3, PAR3, PAR3alpha, PARD-3, PARD3A, SE2-5L16, SE2-5LT1, SE2-5T2
list all proteins Gene Name GeneID UniProt
F2RL2 2151 O00254
F2RL2 14064 O08675
Rat F2RL2 F2RL2 29636 Q920E1

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F2RL2 Proteins (F2RL2) by Origin

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More Proteins for F2RL2 Interaction Partners

Human Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2) interaction partners

  1. These data highlight the importance of the carboxy-terminal motif of the E6 protein and downregulation of PAR3 in tumorigenic transformation of human cervical keratinocytes.

  2. Results suggest that Par3 expression is likely involved in ovarian cancer progression, especially in peritoneal metastasis, probably through modulating IL-6 (show IL6 Proteins) /STAT3 (show STAT3 Proteins) signaling.

  3. reduced keratinocytes Par3 function fosters a permissive P-cadherin-dependent niche for melanocytes transformation, invasion, and metastasis.

  4. These results demonstrate the importance of Par3 and SNAIL (show SNAI1 Proteins) in development of KSHV-induced B-cells cancers

  5. PAR-3 protein expression is frequently lost in primary esophageal squamous cell carcinoma and loss of the PAR-3 protein is associated with aggressive clinicopathological features.

  6. Taken together, these results suggest that the Par3 regulates invasion and metastasis in pancreatic cancers by controlling tight junction assembly via Tiam1 (show TIAM1 Proteins).

  7. PAR3 is essential in thrombin (show F2 Proteins) stimulated insulin (show INS Proteins) secretion.

  8. Knockdown of the polarity protein Par3 reversed the effects of Galpha13 (show GNA13 Proteins) knockdown on cell-cell adhesion and proteolytic invasion in three-dimensional collagen.

  9. Par-3 plays an important role in the modulation of intestinal barrier function by regulating delivery of occludin as well as suppression of MLC phosphorylation.

  10. TFRGAP, a PAR-3 mimicking peptide significantly induced the phosphorylation of eNOS (show NOS3 Proteins)-Thr (show TRH Proteins)-495 with minimal phosphorylation of eNOS (show NOS3 Proteins)-Ser (show SIGLEC1 Proteins)-1177 with no change in nitric oxide production.

Mouse (Murine) Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2) interaction partners

  1. found a hypomethylated region mapping to Iqgap2 (IQ motif-containing GTPase activating protein 2 (show IQGAP2 Proteins)) and F2rl2

  2. Simultaneous depletion of PAR-1 (show MARK2 Proteins) and PAR-3 almost completely inhibited epithelial-mesenchymal transition in bleomycin-induced lung fibrosis.

  3. these data point to a novel kallikrein 6 (show KLK1 Proteins) -signaling axis in neurons that is mediated by PAR1 (show F2R Proteins) and PAR2 (show F2RL1 Proteins) and is positioned to contribute to neurodegeneration

  4. Par3(-/-) mice were protected against ferric chloride-induced thrombosis of mesenteric arterioles and against thromboplastin (show F3 Proteins)-induced pulmonary embolism (protease-activated receptor-3 (PAR3)

  5. PAR3 receptors and analogues can mediate cell signaling by interaction with PAR1 (show F2R Proteins)-type thrombin (show F2 Proteins) receptors

  6. Crystal structures reveal the molecular basis of the cofactor function of cleaved PAR3, bound to exosite I, on recognition of PAR4 (show F2RL3 Proteins) by the active site of thrombin (show F2 Proteins).

F2RL2 Protein Profile

Protein Summary

This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins\; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene.

Alternative names and synonyms associated with F2RL2

  • coagulation factor II (thrombin) receptor-like 2 (f2rl2)
  • coagulation factor II (thrombin) receptor-like 2 (F2RL2)
  • coagulation factor II (thrombin) receptor-like 2 (F2rl2)
  • par-3 family cell polarity regulator (PARD3)
  • par-3 partitioning defective 3 homolog (C. elegans) (PARD3)
  • ASIP protein
  • Baz protein
  • F730031A08 protein
  • PAR-3 protein
  • PAR3 protein
  • PAR3alpha protein
  • PARD-3 protein
  • PARD3A protein
  • SE2-5L16 protein
  • SE2-5LT1 protein
  • SE2-5T2 protein

Protein level used designations for F2RL2

proteinase-activated receptor 3 , Coagulation factor II receptor-like 2 (protease-actovated receptor 3) , protease-activated receptor 3 , proteinase-activated receptor-3 , thrombin receptor-like 2 , PAR-3 , Proteinase activated receptor 3 precursor (PAR-3) (Thrombin receptor-like 2) (Coagulation factor II receptor-like 2) , coagulation factor II receptor-like 2 , CTCL tumor antigen se2-5 , PAR3-alpha , atypical PKC isotype-specific interacting protein , atypical PKC isotype-specific-interacting protein , bazooka , par-3 family cell polarity regulator alpha , par-3 partitioning defective 3 homolog , partitioning defective 3 homolog , par3 , partitioning-defective 3 protein , partitioning-defective protein 3 homolog

GENE ID SPECIES
100148468 Danio rerio
2151 Homo sapiens
14064 Mus musculus
29636 Rattus norvegicus
512581 Bos taurus
56288 Homo sapiens
420468 Gallus gallus
477953 Canis lupus familiaris
527964 Bos taurus
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