Browse our Gap Junction Protein, beta 1, 32kDa Proteins (GJB1)

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Gap Junction Protein, beta 1, 32kDa Proteins (GJB1)
On are 4 Gap Junction Protein, beta 1, 32kDa (GJB1) Proteins from 2 different suppliers available. Additionally we are shipping Gap Junction Protein, beta 1, 32kDa Antibodies (155) and Gap Junction Protein, beta 1, 32kDa Kits (26) and many more products for this protein. A total of 190 Gap Junction Protein, beta 1, 32kDa products are currently listed.
AI118175, CMTX, CMTX1, Cnx32, connexin-30, connexin32, cx30, Cx32, gja1, Gjb-1, GJB1, gjb1-a, GJIC
list all proteins Gene Name GeneID UniProt
GJB1 14618 P28230
Rat GJB1 GJB1 29584 P08033
GJB1 2705 P08034

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Gap Junction Protein, beta 1, 32kDa Proteins (GJB1) by Origin

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More Proteins for Gap Junction Protein, beta 1, 32kDa Interaction Partners

Mouse (Murine) Gap Junction Protein, beta 1, 32kDa (GJB1) interaction partners

  1. Blocking of connexin32 or connexin43 (show GJA1 Proteins) hemichannels decreased serum levels of pro-inflammatory cytokines, and reduced acetaminophen-induced liver injury.

  2. The results of this study indicated that the Leu89Pro substitution in the second transmembrane domain of CX32 disrupts the trafficking of the protein, inhibiting the assembly of CX32 gap junctions, which in turn may result in peripheral neuropathy.

  3. We show that the cell-surface and secreted isoforms of CSF-1 (show CSF1 Proteins) have opposing effects on macrophage activation and disease progression in a mouse model of connexin32-deficientconnexin32-deficient mice

  4. Results identify CSF-1 (show CSF1 Proteins)-activated macrophages as crucial mediators of detrimental Schwann cell dedifferentiation in Cx32-deficient mice

  5. Blockade of endothelial Cx32 increased tissue factor (show F3 Proteins) expression induced by TNF-alpha (show TNF Proteins) stimulation and cell-cell interaction via ICAM1 (show ICAM1 Proteins). Direct Cx32-mediated interaction modulates TF expression in ECs during vascular inflammation.

  6. These findings support a role for Cx32 in non-myelinating and regenerating populations of Schwann cells in normal axonal maintenance in re-myelination, and regeneration of peripheral nerve following injury

  7. Connexin32 interacts with connexin26 (show GJB2 Proteins) and the mitochondrial protein (show COX6B2 Proteins), sideroflexin-1 (show SFXN1 Proteins), at the plasma membrane forming a novel signaling nexus.

  8. These results demonstrate that the incidence of hepatocellular carcinoma increases only in male Cx32KO mice, presumably due to enhanced tumor promotion and progression signals associated with Cx32 deficiency.

  9. Cx32 is differentially phosphorylated and exists in a complex with SAP97 (show DLG1 Proteins) and CaM.

  10. Cx32 therapy improves gap junctional conductance results in larger infarct size, and no antiarrhythmic efficacy.

Human Gap Junction Protein, beta 1, 32kDa (GJB1) interaction partners

  1. Clear clinical/electrophysiological sex differences (intra- and inter family) were shown in patients with hereditary motor-sensory neuropathy 1X with the small es, Cyrillic.259C>G (small er, Cyrillic.P87A) mutation in the GJB1 gene.

  2. In summary, Cx32 is involved in cisplatin resistance, and cytoplasmic Cx32 plays an important role in chemoresistance.

  3. Mutations in noncoding DNA of GJB1 are a major cause of CMTX1 and highlight the importance of mutations in noncoding DNA in human disease.

  4. NMR study of N-terminal mutants of Connexin 26 (show GJB2 Proteins) and Connexin 32

  5. Knockdown of Cx32 by shRNA in HepG2 cells induced EMT (show ITK Proteins), while overexpression of Cx32 converted EMT (show ITK Proteins) to mesenchymal-epithelial transition (MET) in the HepG2/DOX cells. These results suggest that Cx32 is an important regulator of DOX-induced EMT (show ITK Proteins) in hepatocellular carcinoma . Cx32 could be considered as a novel target to reverse DOX resistance in hepatocellular carcinoma

  6. The three novel missense mutations within the GJB1 gene broaden the mutational diversity of X-linked Charcot-Marie-Tooth Disease type I (CMT1X).

  7. A novel point mutation in GJB1 was detected, expanding the spectrum of GJB1 mutations known to be associated with CMTX.

  8. Complete loss of connexin32 function is sufficient to produce central nervous system dysfunction with clinical manifestations.

  9. This study reveals for the first time that Cx43 (show GJA1 Proteins) and Cx32 are down-regulated in keratocystic odontogenic tumours

  10. Transgenic expression of hCx32 in Cx32/Cx47dKO mice resulted in almost complete rescue of behavioral abnormalities in a hypomyelinating leukodystrophy model.

Cow (Bovine) Gap Junction Protein, beta 1, 32kDa (GJB1) interaction partners

  1. intermediate invasive status of bovine trophoblast is supported by the fact that trophoblast giant cells coexpress connexins (Cx)26 (show GJB2 Proteins), Cx32, and Cx43 (show GJA1 Proteins)

Gap Junction Protein, beta 1, 32kDa (GJB1) Protein Profile

Protein Summary

This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Gap Junction Protein, beta 1, 32kDa (GJB1)

  • gap junction protein, beta 1, 32kDa (gjb1)
  • connexin 32 (CX32)
  • connexin 32 (ARALYDRAFT_491086)
  • gap junction protein, beta 1, 32kDa (GJB1)
  • gap junction protein, beta 1 (Gjb1)
  • AI118175 protein
  • CMTX protein
  • CMTX1 protein
  • Cnx32 protein
  • connexin-30 protein
  • connexin32 protein
  • cx30 protein
  • Cx32 protein
  • gja1 protein
  • Gjb-1 protein
  • GJB1 protein
  • gjb1-a protein
  • GJIC protein

Protein level used designations for GJB1

connexin 30 , connexin 32 , gap junction protein, beta 1, 32kDa , connexin-32 , connexin-43 , gap junction beta-1 protein , gap junction membrane channel protein beta 1 , GAP junction 28 kDa liver protein , connexin32 , cx32 , gap junction protein, beta 1, 32 kD , gap junction protein beta 1 , connexin-30 , cx30

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281194 Bos taurus
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100034021 Equus caballus
394373 Xenopus laevis
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