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GJB1 Products

(Gap Junction Protein, beta 1, 32kDa (GJB1))
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2008].

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Featured GJB1 Categories

GJB1 Antibodies

High quality antibodies with extensive validation data.

GJB1 ELISA Kits

Reliable ELISA kits for a wide range of species.

GJB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GJB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN2774855
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC, ELISA, ICC
Validations
  • (3)
Cat. No. ABIN6260962
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7153605
Quantity 100 μg
Datasheet Datasheet

Recommended GJB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966959
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956052
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN509971
Quantity 96 tests
Datasheet Datasheet

Recommended GJB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355139
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355137
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396454
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GJB1 products

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Hoek, Schlegel, Eichhoff, Widmer, Praetorius, Einarsson, Valgeirsdottir, Bergsteinsdottir, Schepsky, Dummer, Steingrimsson: "Novel MITF targets identified using a two-step DNA microarray strategy." in: Pigment cell & melanoma research, Vol. 21, Issue 6, pp. 665-76, (2008) (PubMed).

Dagli, Yamasaki, Krutovskikh, Omori: "Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver." in: Carcinogenesis, Vol. 25, Issue 4, pp. 483-92, (2004) (PubMed).

Kocha?ski, Kabzi?ska: "Molecular genetic analysis of the GJB1 gene: a study of six mutations." in: Journal of applied genetics, Vol. 45, Issue 1, pp. 95-100, (2004) (PubMed).

Wang, Chang, Yeh, Wu, Chen, Wu: "Functional analysis of connexin-32 mutants associated with X-linked dominant Charcot-Marie-Tooth disease." in: Neurobiology of disease, Vol. 15, Issue 2, pp. 361-70, (2004) (PubMed).

Ma, Ma, Sui, Wang, Wang: "Signal transduction of gap junctional genes, connexin32, connexin43 in human hepatocarcinogenesis." in: World journal of gastroenterology : WJG, Vol. 9, Issue 5, pp. 946-50, (2003) (PubMed).

Sahin, Tan, Kalay, Calapoglu, Karaguzel: "Connexin 32 mutation in a Turkish family with X-linked Charcot-Marie-Tooth disease." in: The International journal of neuroscience, Vol. 113, Issue 6, pp. 777-85, (2003) (PubMed).

Yang, Ichikawa, Tsuchiya: "A novel function of connexin 32: marked enhancement of liver function in a hepatoma cell line." in: Biochemical and biophysical research communications, Vol. 307, Issue 1, pp. 80-5, (2003) (PubMed).

Bondurand, Girard, Pingault, Lemort, Dubourg, Goossens: "Human Connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10." in: Human molecular genetics, Vol. 10, Issue 24, pp. 2783-95, (2001) (PubMed).

Corcos, Lafrenière, Begy, Loch-Caruso, Willard, Glover: "Refined localization of human connexin32 gene locus, GJB1, to Xq13.1." in: Genomics, Vol. 13, Issue 2, pp. 479-80, (1992) (PubMed).

Synonyms and alternative names related to GJB1

gap junction protein beta 1 (gjb1), connexin 32 (CX32), probable serine/threonine-protein kinase CST (LOC9303136), gap junction protein beta 1 (GJB1), gap junction protein, beta 1 (Gjb1), gap junction protein beta 1 (Gjb1), gap junction protein beta 1 L homeolog (gjb1.L), AI118175, cmtx, CMTX, cmtx1, CMTX1, Cnx32, connexin-30, connexin32, cx30, cx32, CX32, Cx32, gja1, Gjb-1, GJB1, gjb1-a, GJIC

Protein level used designations for GJB1

  • connexin 30
  • connexin 32
  • gap junction protein, beta 1, 32kDa
  • connexin-32
  • connexin-43
  • gap junction beta-1 protein
  • gap junction membrane channel protein beta 1
  • GAP junction 28 kDa liver protein
  • connexin32
  • cx32
  • gap junction protein, beta 1, 32 kD
  • gap junction protein beta 1
  • connexin-30
  • cx30
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