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Human ITGB1 ELISA Kit for Sandwich ELISA - ABIN417575
Gupta, Khan, Kumar, Kumar, Sharma: Versican and its associated molecules: potential diagnostic markers for multiple myeloma. in Clinica chimica acta; international journal of clinical chemistry 2015
Findings demonstrate the neurotrophin (show BDNF ELISA Kits), BDNF (show BDNF ELISA Kits)-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG ELISA Kits) .
Findings identify beta(1)-integrin as an important functional cargo during Ca(2+)-dependent rapid endocytosis stimulated by a diffusible guidance cue in Xenopus spinal neurons.
Itgb1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of Sharpin (show SHARPIN ELISA Kits)-deficient mice.
Taken together, acid-induced acute lung injury results in epithelial microvesicle shuttling of miR-17/221 that in turn modulates macrophage beta1 integrin recycling, promoting macrophage recruitment and ultimately contributing to lung inflammation.
Type I collagen was highly expressed in the spinal cord during the scar-forming phase and induced astrocytic scar formation via the integrin-N-cadherin (show CDH2 ELISA Kits) pathway.
the transcription regulators YAP (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.
Itgb1 is an essential niche molecule that maintains satellite cell (SC) homeostasis, and sustains the expansion and self-renewal of this stem cell pool during regeneration. We further show that Itgb1 cooperates with fibroblast growth factor 2 (Fgf2 (show FGF2 ELISA Kits)), a potent growth factor for SCs (show TWIST1 ELISA Kits), to synergistically activate their common downstream effectors, the mitogen-activated protein (MAP) kinase Erk (show MAPK1 ELISA Kits) and protein kinase B (Akt (show AKT1 ELISA Kits)).
this study shows that alpha4beta1 integrin mediates memory CD8 (show CD8A ELISA Kits)+ T cells accumulation in salivary glands after infection with lymphocytic choriomeningitis virus
FAK sustained the active integrin conformation by maintaining talin association with Rab11 endosomes in a type I phosphatidylinositol phosphate kinase (PIPKIgamma)-dependent manner.
results demonstrate that c-Cbl (show CBL ELISA Kits) mediates the ubiquitination/degradation of integrin beta1, which leads to COMP (show COMP ELISA Kits) deficiency-induced dilated cardiomyopathy.
Ptrh2 (show PTRH2 ELISA Kits) levels were up-regulated in dystrophin (show DMD ELISA Kits) deficient mdx (show DMD ELISA Kits) muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx (show DMD ELISA Kits) muscle and Duchenne muscular dystrophy (show DMD ELISA Kits) patients. Similar to the a7 integrin, Ptrh2 (show PTRH2 ELISA Kits) expression was decreased in laminin-a2 null gastrocnemius muscle
this study has identified a new role for Parvin (show PARVA ELISA Kits) and alphaPix (show ARHGEF6 ELISA Kits) downstream of the integrin-ILK (show ILK ELISA Kits) signaling axis for mammary epithelial cell differentiation.
alpha5beta1 integrin can stimulate drug resistance in cancer cells via a mechanism based on inhibition of protein kinase (show CDK7 ELISA Kits) Erk (show EPHB2 ELISA Kits).
We measured the effect of recombinant Gal-3 (show LGALS3 ELISA Kits) added exogenously on the lateral mobility of the alpha5b1 integrin on HeLa cells. Using single-particle tracking (SPT (show AGXT ELISA Kits)) we detected increased lateral mobility of the integrin in the presence of Gal-3 (show LGALS3 ELISA Kits), while its truncated C-terminal domain (Gal (show GAL ELISA Kits)-3C) showed only minor reductions in lateral mobility.
By directly binding to the 3'UTRs of ITGA6 (show ITGA6 ELISA Kits) and ITGB1, we found miR (show MLXIP ELISA Kits)-30e-5p to suppress mainly the adhesion of ITGA6 (show ITGA6 ELISA Kits) in CRC (show CALR ELISA Kits) cells to laminin.Taken together, miR (show MLXIP ELISA Kits)-30e-5p is a novel effector of P53 (show TP53 ELISA Kits)-induced suppression of migration, invasion and metastasis
These data outline a new signaling mechanism by which KCa1.1 (show KCNMA1 ELISA Kits) regulates beta1-integrin function and therefore invasiveness of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs).
sp(2) -Iminosugar alpha-glucosidase (show AGLU ELISA Kits) inhibitor 1 (show PPP1R1A ELISA Kits)-C-octyl-2-oxa-3-oxocastanospermine inhibits breast cancer cell migration via beta1-integrin, Stim1 (show STIM1 ELISA Kits), and FAK (show PTK2 ELISA Kits) signaling pathways.
beta1-integrin expression is regulated in pancreatic and colon cancer cells by the pro-oncogenic orphan nuclear receptor (show ESRRB ELISA Kits) 4A1
The SALL4 (show SALL4 ELISA Kits) - integrin alpha6 - integrin beta1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells.
membrane-proximal N-glycosylation is critical for intermolecular interactions between integrin beta1 and other cell membrane proteins, such as syndecan-4 (show SDC4 ELISA Kits) and epidermal growth factor receptor (show EGFR ELISA Kits). Moreover, alpha2,6-sialylation is required for beta1 activation
High ITGB1 expression is associated with lung metastasis in ovarian cancer.
the loss of MUC16 (show MUC16 ELISA Kits) and E-cadherin (show CDH1 ELISA Kits) expression resulted in the formation of more compact spheroids. In addition, our data describe an unusual link between E-cadherin (show CDH1 ELISA Kits) expression and less compact spheroids. Our data also emphasize the role of MUC16 (show MUC16 ELISA Kits) and b1 integrin in Epithelial ovarian cancer (EOC) spheroid formation.
beta1-integrin antigen-antibody interactions and the distribution of beta1-integrin protein on spermatogonial stem cell membrane were demonstrated using atomic force microscopy
The overall findings suggest that the secreted galectin-3 (show LGALS3 ELISA Kits) stimulated by PGF (show PGF ELISA Kits) plays a role in structural luteolysis by binding to beta 1 integrin.
Putative function of fibronectin (show FN1 ELISA Kits) and its receptor (integrin alpha(5 (show ITGA5 ELISA Kits))beta(1)) in male and female gametes during bovine fertilization in vitro.
integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk association at integrin sites, where it plays a role in downstream, shear-stimulated myosin light chain diphosphorylation.
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
both the gpIb-VWF (show VWF ELISA Kits) interaction and the integrin alpha(2 (show ITGA2 ELISA Kits))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 ELISA Kits))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF ELISA Kits) is bound
TRPV4 (show TRPV4 ELISA Kits) channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
integrin beta 1
, integrin beta-1*
, integrin beta-1-B
, VLA-4 subunit beta
, fibronectin receptor subunit beta
, integrin beta-1
, beta OL
, beta oligodendroglia
, integrin VLA-4 subunit beta
, integrin beta 1 (fibronectin receptor beta)
, glycoprotein IIa
, integrin VLA-4 beta subunit
, very late activation protein, beta polypeptide
, integrin beta-1 subunit
, CSAT antigen
, JG22 antigen
, Fibronectin receptor subunit beta
, Integrin VLA-4 subunit beta
, Integrin subunit beta-1