Browse our anti-Cyclin D2 (CCND2) Antibodies

Full name:
anti-Cyclin D2 Antibodies (CCND2)
On www.antibodies-online.com are 190 Cyclin D2 (CCND2) Antibodies from 27 different suppliers available. Additionally we are shipping Cyclin D2 Kits (41) and Cyclin D2 Proteins (18) and many more products for this protein. A total of 255 Cyclin D2 products are currently listed.
Synonyms:
2600016F06Rik, AI256817, BF642806, C86853, CCND2, cD2, KIAK0002, LOC100224096, si:ch211-240j22.2, Vin-1, Vin1, zgc:162280
list all antibodies Gene Name GeneID UniProt
CCND2 894 P30279
CCND2 12444 P30280
CCND2 64033 Q04827

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Most Popular Reactivities for anti-Cyclin D2 (CCND2) Antibodies

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anti-Human Cyclin D2 Antibodies:

anti-Mouse (Murine) Cyclin D2 Antibodies:

anti-Rat (Rattus) Cyclin D2 Antibodies:

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Top referenced anti-Cyclin D2 Antibodies

  1. Human Monoclonal Cyclin D2 Primary Antibody for WB - ABIN393662 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 5 references for 393662

  2. Human Polyclonal Cyclin D2 Primary Antibody for WB - ABIN658342 : Park, Chun, Bae, Park, Cheong, Lee, Kim, Shin: CCND2 polymorphisms associated with clearance of HBV infection. in Journal of human genetics 2010 (PubMed)
    Show all 3 references for 658342

  3. Human Monoclonal Cyclin D2 Primary Antibody for IF, WB - ABIN1106875 : Kozar, Ciemerych, Rebel, Shigematsu, Zagozdzon, Sicinska, Geng, Yu, Bhattacharya, Bronson, Akashi, Sicinski: Mouse development and cell proliferation in the absence of D-cyclins. in Cell 2004 (PubMed)
    Show all 3 references for 1106875

  4. Human Polyclonal Cyclin D2 Primary Antibody for ICC, IF - ABIN4301609 : Danielsson, Wiking, Mahdessian, Skogs, Ait Blal, Hjelmare, Stadler, Uhlén, Lundberg: RNA deep sequencing as a tool for selection of cell lines for systematic subcellular localization of all human proteins. in Journal of proteome research 2013 (PubMed)
    Show all 2 references for 4301609

  5. Human Monoclonal Cyclin D2 Primary Antibody for IHC (fro), IF - ABIN264332 : Lukas, Bartkova, Welcker, Petersen, Peters, Strauss, Bartek: Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types. in Oncogene 1995 (PubMed)
    Show all 2 references for 264332

  6. Human Polyclonal Cyclin D2 Primary Antibody for ELISA, WB - ABIN1450707 : Xiong, Menninger, Beach, Ward: Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins. in Genomics 1992 (PubMed)
    Show all 2 references for 1450707

  7. Human Polyclonal Cyclin D2 Primary Antibody for ELISA, WB - ABIN1532139 : Palmero, Holder, Sinclair, Dickson, Peters: Cyclins D1 and D2 are differentially expressed in human B-lymphoid cell lines. in Oncogene 1993 (PubMed)
    Show all 2 references for 1532139

  8. Human Polyclonal Cyclin D2 Primary Antibody for IF (cc), IF (p) - ABIN738366 : Wang, Wu, Gao, Chen, Gu, Ding, Guo: Elevated toll-like receptor 3 inhibits pancreatic ?-cell proliferation through G1 phase cell cycle arrest. in Molecular and cellular endocrinology 2013 (PubMed)

More Antibodies against Cyclin D2 Interaction Partners

Human Cyclin D2 (CCND2) interaction partners

  1. data suggested that loss of CCND2 expression is closely associated with the promoter aberrant methylation

  2. MiR (show MLXIP Antibodies)-497 significantly suppressed cell proliferation by arresting the cell cycle through the CCND2 protein.

  3. cyclin D2 acts as regulator of cell cycle (show C13orf15 Antibodies) proteins affecting SAMHD1 (show SAMHD1 Antibodies)-mediated HIV-1 restriction in non-proliferating macrophages.

  4. CCND2-AS1 (show PTGDR Antibodies) promotes glioma cells proliferation and growth in a process that involves Wnt (show WNT2 Antibodies) and beta-catenin (show CTNNB1 Antibodies)

  5. CCND1 (show CCND1 Antibodies) is downregulated, whereas CCND2 is not, following ionizing radiation (IR) . Both CCND1 (show CCND1 Antibodies)- and CCND2-expressing MM cells arrested in S/G2 (show STRN3 Antibodies)/M, and did not differ in other cell-cycle proteins or sensitivity to IR.Differential expression of D-cyclin (show PCNA Antibodies) does not appear to affect cell-cycle response to IR, and is unlikely to underlie differential sensitivity to DNA damage.

  6. the phosphorylation levels of ErbB2 (show ERBB2 Antibodies), ErbB3 (show ERBB3 Antibodies) and Akt (show AKT1 Antibodies) and the protein levels of cyclin D1 (show CCND1 Antibodies) were decreased by lapatinib treatment of HSC3, HSC4 and Ca9 (show CA9 Antibodies)-22 cells

  7. miR (show MLXIP Antibodies)-155 overexpression plays a promoting role in the proliferative, migratory and invasive behavior of OSCC cells. Its effects on OSCC are possibly associated with its regulation of the BCL6 (show BCL6 Antibodies)/cyclin D2 axis.

  8. Bioinformatics analysis further revealed cyclin D2 (CCND2) and AKT3 (show AKT3 Antibodies), putative tumor promoters, as potential targets of miR610. Data from reporter assays showed that miR610 directly binds to the 3'untranslated

  9. this study shows that miR (show MLXIP Antibodies)-124-3p may negatively regulate the transcription of the STAT3 (show STAT3 Antibodies) by interfering with its 3'UTR (show UTS2R Antibodies), and the degradation of STAT3 (show STAT3 Antibodies) affects its downstream expression of such as p-STAT3 (show STAT3 Antibodies), CCND2 and MMP-2 (show MMP2 Antibodies)

  10. these results highlight the impact of CCND2 3'UTR (show UTS2R Antibodies) shortening on miRNA-dependent regulation of CCND2 in multiple myeloma.

Mouse (Murine) Cyclin D2 (CCND2) interaction partners

  1. cyclin D2 acts as regulator of cell cycle (show C13orf15 Antibodies) proteins affecting SAMHD1 (show SAMHD1 Antibodies)-mediated HIV-1 restriction in non-proliferating macrophages.

  2. Data (including data from studies in transgenic and knockout mice) suggest that Pkcz (protein kinase C zeta (show PRKCZ Antibodies)) activation is key for early compensatory pancreatic beta-cell proliferation in insulin (show INS Antibodies) resistance (overweight and diabetes type 2) by regulating downstream signal transduction components mTOR (mammalian target of rapamycin (show FRAP1 Antibodies) protein) and Ccnd2 (cyclin-D2).

  3. miR (show MLXIP Antibodies)-26a regulated mouse hepatocyte proliferation by directly targeting the 3' untranslated regions of cyclin D2/cyclin E2 (show CCNE2 Antibodies).

  4. NF-kappaB (show NFKB1 Antibodies)-miR (show MLXIP Antibodies)-195/497-Igf1r (show IGF1R Antibodies)/Insr (show INSR Antibodies)-Ccnd2/Ccne1 (show CCNE1 Antibodies) plays important roles in myogenesis.

  5. Loss of N-myc (show MYCN Antibodies) significantly impairs the Sonic hedgehog (show SHH Antibodies) signaling pathway and disrupts the expression of cell cycle effectors with a significant reduction of Ccnd2.

  6. Activation of the ERK1/2 (show MAPK1/3 Antibodies) signalling pathway, increased phosphorylation of c-myc (show MYC Antibodies) and significantly increased expression of cyclin D2 protein, are demonstrated.

  7. Hippocampus-dependent learning was not generally impaired in Ccnd2 knockout mice, but specifically functional aspects of maze learning were affected.

  8. FGF2 signaling results in the phosphorylation of Erk1/2, and activation of c-Fos and c-Jun that lead to elevated cyclin D mRNA levels.

  9. Islet ARNT (show ARNT Antibodies) increases in normal murine pregnancy and beta-cell ARNT (show ARNT Antibodies) is required for cyclinD2 induction and increased beta-cell proliferation in pregnancy.

  10. Study reveals molecular insight into how the Ets (show ETS1 Antibodies) family transcription factor Pea3 (show ETV4 Antibodies) favors EMT (show ITK Antibodies) and contributes to tumorigenesis via a negative regulatory loop with Cyclin D2, a new Pea3 (show ETV4 Antibodies) target gene.

Pig (Porcine) Cyclin D2 (CCND2) interaction partners

  1. maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 and PSEN1 (show PSEN1 Antibodies) genes via a STAT3 (show STAT3 Antibodies)-dependent pathway

Cyclin D2 (CCND2) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

Alternative names and synonyms associated with Cyclin D2 (CCND2)

  • cyclin D2, b (ccnd2b) antibody
  • cyclin D2 (ccnd2-b) antibody
  • cyclin D2 (CCND2) antibody
  • cyclin D2 (ccnd2) antibody
  • G1/S-specific cyclin-D2 (ccnd2) antibody
  • cyclin D2, a (ccnd2a) antibody
  • cyclin D2 (LOC100224096) antibody
  • cyclin D1 (CCND1) antibody
  • cyclin D2 (Ccnd2) antibody
  • cyclin D2 (ccnd2-a) antibody
  • 2600016F06Rik antibody
  • AI256817 antibody
  • BF642806 antibody
  • C86853 antibody
  • CCND2 antibody
  • cD2 antibody
  • KIAK0002 antibody
  • LOC100224096 antibody
  • si:ch211-240j22.2 antibody
  • Vin-1 antibody
  • Vin1 antibody
  • zgc:162280 antibody

Protein level used designations for anti-Cyclin D2 (CCND2) Antibodies

cyclin D2 , G1/S-specific cyclin-D2 , ccnd2 , G1/S-specific cyclin D2 , vin-1 proto-oncogene

GENE ID SPECIES
565038 Danio rerio
734882 Xenopus laevis
747123 Pan troglodytes
779063 Xenopus laevis
100038071 Xenopus (Silurana) tropicalis
100195486 Salmo salar
799608 Danio rerio
100224096 Taeniopygia guttata
100009036 Oryctolagus cuniculus
894 Homo sapiens
12444 Mus musculus
64033 Rattus norvegicus
100730596 Cavia porcellus
397162 Sus scrofa
615414 Bos taurus
374047 Gallus gallus
611782 Canis lupus familiaris
100147799 Ovis aries
373667 Xenopus laevis
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