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Browse our Cyclin H Proteins (CCNH)

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Cyclin H Proteins (CCNH)
On are 14 Cyclin H (CCNH) Proteins from 6 different suppliers available. Additionally we are shipping Cyclin H Antibodies (112) and Cyclin H Kits (25) and many more products for this protein. A total of 164 Cyclin H products are currently listed.
142767_at, 6330408H09Rik, ACYPI004637, AI661354, AV102684, AW538719, CAK, ccnh, ccnh-A, CG7405, Cych, Cyclin-H, Dmel\\CG7405, p34, p37, zgc:114132
list all proteins Gene Name GeneID UniProt
CCNH 902 P51946
CCNH 66671 Q61458
CCNH 84389 Q9R1A0

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Cyclin H Proteins (CCNH) by Origin

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Top referenced Cyclin H Proteins

  1. Human Cyclin H Protein expressed in Escherichia coli (E. coli) - ABIN666973 : Schneider, Montenarh, Wagner: Regulation of CAK kinase activity by p53. in Oncogene 1998 (PubMed)
    Show all 2 references for ABIN666973

More Proteins for Cyclin H Interaction Partners

Zebrafish Cyclin H (CCNH) interaction partners

  1. Cyclin H is implicated in the regulation of the transcriptional machinery during midblastula transition and is therefore an essential gene in early zebrafish larval development.

Human Cyclin H (CCNH) interaction partners

  1. Our results indicated that CCNH/CDK7 (show CDK7 Proteins)-CtBP2 (show CTBP2 Proteins) axis may augment ESCC cell migration, and targeting the interaction of both may provide a novel therapeutic target of esophageal squamous cell carcinoma .

  2. SNPs in CCNH and ABCG2 can modulate the development of severe oxaliplatin-induced peripheral neuropathy.

  3. Hemodynamic forces modulate EC proliferative phenotype through the miR (show MLXIP Proteins)-23b/CAK/cyclin H pathway.

  4. When considering all thyroid cancer (DTC) cases, only rs2230641 (CCNH) was associated with DTC risk.

  5. CCNH and CDK7 (show CDK7 Proteins) may play an important role in the tumorigenesis and development of esophageal squamous cell carcinoma.

  6. High Cyclin H is associated with gastrointestinal stromal tumours.

  7. The expression of cyclin H and CDK7 (show CDK7 Proteins) protein in proliferating hemangiomas was significantly higher than that in involuting hemangiomas and normal skin tissues.

  8. The cyclin H/cdk7 (show CDK7 Proteins)/Mat1 (show MAT1A Proteins) kinase activity is regulated by CK2 (show CSNK2A1 Proteins) phosphorylation of cyclin H.

  9. Confocal microscopy revealed the co-localization of PKC (show PRRT2 Proteins)-iota with CAK/cdk7 (show CDK7 Proteins) in both the cytoplasm and nucleus of U-373 MG glioma cells, supporting its role in cell signaling

  10. In response to ATRA, PML (show PML Proteins)/RARalpha (show RARA Proteins) is dissociated from CAK, leading to MAT1 (show MAT1A Proteins) degradation, G1 arrest, and decreased CAK phosphorylation of PML (show PML Proteins)/RARalpha (show RARA Proteins)

Pig (Porcine) Cyclin H (CCNH) interaction partners

  1. CDK7 (show CDK7 Proteins) and CCNH activate CDC2 (show CDK1 Proteins) by T161 phosphorylation and make up CDK-activating kinase (show CDK7 Proteins), which is required for normal meiotic progression during porcine oocyte maturation.

Mouse (Murine) Cyclin H (CCNH) interaction partners

  1. investigated the function of the Cdk7 (show CDK7 Proteins).cyclin (show PCNA Proteins) H.Mat1 complex in murine embryonic stem (ES) cells and preimplantation embryos to determine whether it regulates the unique cell cycle structure and transcriptional network of pluripotent cells

Cyclin H (CCNH) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Cyclin H (CCNH)

  • cyclin H (CCNH)
  • cyclin H (ccnh)
  • cyclin h (AaeL_AAEL013248)
  • Cyclin H (Cych)
  • Cyclin H (CycH)
  • CYclin H (cyh-1)
  • cyclin H (Ccnh)
  • 142767_at protein
  • 6330408H09Rik protein
  • ACYPI004637 protein
  • AI661354 protein
  • AV102684 protein
  • AW538719 protein
  • CAK protein
  • ccnh protein
  • ccnh-A protein
  • CG7405 protein
  • Cych protein
  • Cyclin-H protein
  • Dmel\\CG7405 protein
  • p34 protein
  • p37 protein
  • zgc:114132 protein

Protein level used designations for Cyclin H Proteins (CCNH)

cyclin-H , cyclin h , Cyclin H , cyclin H , CG7405-PA , CycH-PA , CyclinH , CYclin H family member (cyh-1) , CAK complex subunit , CDK-activating kinase complex subunit , MO15-associated protein , cyclin-dependent kinase-activating kinase complex subunit , p36

100065185 Equus caballus
541325 Danio rerio
549010 Xenopus (Silurana) tropicalis
5577539 Aedes aegypti
100163558 Acyrthosiphon pisum
100194548 Salmo salar
100294622 Pongo abelii
40429 Drosophila melanogaster
427328 Gallus gallus
739351 Pan troglodytes
190078 Caenorhabditis elegans
100528117 Ictalurus punctatus
902 Homo sapiens
100310796 Sus scrofa
615512 Bos taurus
66671 Mus musculus
84389 Rattus norvegicus
479156 Canis lupus familiaris
394356 Xenopus laevis
101104905 Ovis aries
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