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Cyclin H Products

(Cyclin H (CCNH))

Categories

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010].

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Featured Cyclin H Categories

Cyclin H Antibodies

High quality antibodies with extensive validation data.

Cyclin H ELISA Kits

Reliable ELISA kits for a wide range of species.

Cyclin H Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cyclin H Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (6)
Cat. No. ABIN560218
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (5)
Cat. No. ABIN3021259
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7266569
Quantity 100 μL
Datasheet Datasheet

Recommended Cyclin H ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380396
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1745484
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1744265
Quantity 96 tests
Datasheet Datasheet

Recommended Cyclin H Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348473
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348475
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090783
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Cyclin H products

Schütz, Wangen, Sommerer, Kögler, Eickhoff, Degenhart, Klebl, Naing, Egilmezer, Hamilton, Rawlinson, Sticht, Marschall: "Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency." in: Virus research, Vol. 335, pp. 199200, (2023) (PubMed).

Nakazawa, Sasaki, Mitsutake, Matsuse, Shimada, Nardo, Takahashi, Ohyama, Ito, Mishima, Nomura, Kinoshita, Ono, Takenaka, Masuyama, Kudo, Slor, Utani, Tateishi, Yamashita, Stefanini, Lehmann, Yoshiura et al.: "Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. ..." in: Nature genetics, Vol. 44, Issue 5, pp. 586-92, (2012) (PubMed).

Prohaska, Williams: "Assembly of the Trypanosoma brucei 60S ribosomal subunit nuclear export complex requires trypanosome-specific proteins P34 and P37." in: Eukaryotic cell, Vol. 8, Issue 1, pp. 77-87, (2009) (PubMed).

Synonyms and alternative names related to Cyclin H

cyclin H (CCNH), cyclin H (ccnh), cyclin-H (LOC5577539), cyclin H (Cych), Cyclin H (CycH), CYclin H (cyh-1), cyclin H (Ccnh), cyclin H L homeolog (ccnh.L), 142767_at, 6330408H09Rik, ACYPI004637, AI661354, AV102684, AW538719, cak, CAK, ccnh, ccnh-A, CG7405, Cych, Cyclin-H, Dmel\\CG7405, p34, p37, zgc:114132

Protein level used designations for Cyclin H

  • cyclin-H
  • cyclin h
  • Cyclin H
  • cyclin H
  • CG7405-PA
  • CycH-PA
  • CyclinH
  • CYclin H family member (cyh-1)
  • CAK complex subunit
  • CDK-activating kinase complex subunit
  • MO15-associated protein
  • cyclin-dependent kinase-activating kinase complex subunit
  • p36
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