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Browse our GADD45B Proteins (GADD45B)

Full name:
Growth Arrest and DNA-Damage-Inducible, beta Proteins (GADD45B)
On are 15 Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Proteins from 8 different suppliers available. Additionally we are shipping GADD45B Antibodies (27) and many more products for this protein. A total of 48 GADD45B products are currently listed.
AI323528, cb196, CS131, gadd45b, gadd45b2, GADD45BETA, MYD118, sb:cb196, wu:fa92d10, wu:fa98h12, wu:fk65h03, zgc:73104, zgc:111973
list all proteins Gene Name GeneID UniProt
GADD45B 17873 P22339
GADD45B 4616 O75293
GADD45B 299626  

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GADD45B Proteins (GADD45B) by Origin

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Top referenced GADD45B Proteins

  1. Human GADD45B Protein expressed in Escherichia coli (E. coli) - ABIN666871 : Takekawa, Saito: A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. in Cell 1998 (PubMed)
    Show all 2 references for ABIN666871

More Proteins for GADD45B Interaction Partners

Zebrafish Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) interaction partners

  1. investigated the functional effects of Coiled-Coil Domain Containing 80-loss-of-function during embryonic development and verified its interaction with gadd45beta2 in somitogenesis

  2. regulated expression of gadd45beta genes in the anterior PSM is required for somite segmentation.

Mouse (Murine) Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) interaction partners

  1. Gadd45b mediates the action of electroconvulsive shock-induced neural stem cell proliferation in the hippocampus.

  2. Results suggest the possibility that differential Gadd45a (show GADD45A Proteins), Gadd45b and Gadd45g (show GADD45G Proteins) expression during development affects neurons, contributing cortical evolution and diversity

  3. Hepatic oxidative stress activates the Gadd45b gene by way of degradation of the transcriptional repressor STAT3 (show STAT3 Proteins).

  4. Modulation of the TGFbeta (show TGFB1 Proteins)/NFkappaB/Gadd45b signaling pathway may provide a means to enhance the neuroprotective effect of Gadd45b in RGCs.

  5. These results implicate Gadd45b as a learning-induced gene and a regulator of memory formation and are consistent with its potential role in active DNA demethylation in memory.

  6. The data suggest that GADD45beta plays a complex role in regulating adaptive immunity and, depending on the model, either enhances or suppresses inflammation.

  7. The current studies suggest that Gadd45b may be important for long-term hippocampus-dependent memory storage.

  8. these data highlight a novel role for both Gadd45a (show GADD45A Proteins) and Gadd45b in myeloid innate immune functions by differential modulation of p38 (show CRK Proteins) and JNK (show MAPK8 Proteins) signaling in granulocytes compared to macrophages.

  9. Gadd45a (show GADD45A Proteins), Gadd45b and Gadd45g (show GADD45G Proteins) expression during mouse embryonic development.

  10. defined separate Gadd45beta domains that mediated binding to CAR and transcriptional activation

Human Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) interaction partners

  1. The gadd45b gene has both tumor suppressor and tumor promoter functions, dependent on the tissue/cell type and transforming event. (Review)

  2. Gadd45B protects the liver through two entirely different processes: binding MKK7 (show MAP2K7 Proteins) to block damaging signal transduction or binding CAR to coactivate anabolic transcription. (Review)

  3. as such may play an unappreciated role in tumorigenesis. The exact mechanism of GADD45B inactivation and overexpression requires further investigation. GADD45B could be a potential therapeutic target for CRC (show CALR Proteins) treatment in future

  4. Cadmium chloride can induce DNA damage and increase expression levels of the gadd153 (show DDIT3 Proteins) and gadd45beta promoters in HepG2 cells.

  5. finding show there is an increased expression and decreased promoter binding of GADD45b in psychotic subjects.

  6. GADD45beta is a novel pituitary tumor suppressor whose reexpression blocks proliferation, survival, and tumorigenesis

  7. The association of GADD45beta expression and pathological grading of chondrosarcoma in the present study suggests that the immunohistochemical study of GADD45beta may be a specific diagnostic parameter for chondrosarcoma cell differentiation.

  8. PXR (show NR1I2 Proteins) activates the GADD45beta gene, increasing p38 MAPK (show MAPK14 Proteins) phosphorylation, and leading HepG2 cells to change morphology and migrate.

  9. Findings suggest that GADD45beta induction contributes to sorafenib-induced apoptosis in HCC (show FAM126A Proteins) cells, prompting further studies to validate its potential value in predicting sorafenib efficacy.

  10. Findings suggest that Gadd45b mediates p38 (show CRK Proteins)-induced Rb phosphorylation by enhancing the interaction between p38 (show CRK Proteins) and Rb during Fas (show FAS Proteins)-induced apoptosis in murine hepatocytes.

GADD45B Protein Profile

Protein Summary

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

Alternative names and synonyms associated with GADD45B

  • growth arrest and DNA-damage-inducible, beta a (gadd45ba)
  • growth arrest and DNA-damage-inducible, beta (GADD45B)
  • growth arrest and DNA-damage-inducible 45 beta (Gadd45b)
  • growth arrest and DNA-damage-inducible, beta (Gadd45b)
  • AI323528 protein
  • cb196 protein
  • CS131 protein
  • gadd45b protein
  • gadd45b2 protein
  • GADD45BETA protein
  • MYD118 protein
  • sb:cb196 protein
  • wu:fa92d10 protein
  • wu:fa98h12 protein
  • wu:fk65h03 protein
  • zgc:73104 protein
  • zgc:111973 protein

Protein level used designations for GADD45B

gadd , growth arrest and DNA damage 45 beta , Myeloid differentiation primary response protein MyD118 , growth arrest and DNA damage-inducible protein GADD45 beta , growth arrest and DNA-damage-inducible protein GADD45 beta , myeloid differentiation primary response gene 118 , myeloid differentiation primary response protein MyD118 , negative growth regulatory protein MyD118 , myeloid differentiation primary response , growth arrest and DNA-damage-inducible 45 beta

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