GADD45B Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721555

Product Details

Target: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GADD45B protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human GADD45B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Alternative Name: Gadd45b (GADD45B Products)

Synonyms: GADD45BETA Protein, MYD118 Protein, AI323528 Protein, Myd118 Protein, CS131 Protein, cb196 Protein, gadd45b Protein, gadd45b2 Protein, sb:cb196 Protein, zgc:73104 Protein, gadd45beta Protein, wu:fa92d10 Protein, wu:fa98h12 Protein, wu:fk65h03 Protein, zgc:111973 Protein, gadd45b1 Protein, gadd45bl Protein, zgc:112453 Protein, growth arrest and DNA damage inducible beta Protein, growth arrest and DNA-damage-inducible 45 beta Protein, growth arrest and DNA-damage-inducible, beta Protein, growth arrest and DNA-damage-inducible, beta a Protein, growth arrest and DNA-damage-inducible, beta b Protein, GADD45B Protein, Gadd45b Protein, gadd45ba Protein, gadd45bb Protein

Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

Molecular Weight: 17.6 kDa

NCBI Accession: NP_056490

Pathways: Cell Division Cycle