Browse our RBX1 Proteins (RBX1)

On are 8 Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) Proteins from 4 different suppliers available. Additionally we are shipping RBX1 Antibodies (65) and many more products for this protein. A total of 75 RBX1 products are currently listed.
1500002P15Rik, AA517855, ATRBX1, BA554C12.1, F7C8.160, F7C8_160, hop21, HRT1, im:7137515, RBX1, REGULATOR OF CULLINS-1, RING-box 1, RNF75, ROC1, zgc:136444
list all proteins Gene Name GeneID UniProt
RBX1 9978 P62877
RBX1 56438 P62878
Rat RBX1 RBX1 300084  

RBX1 Proteins (RBX1) by Origin

More Proteins for RBX1 Interaction Partners

Caenorhabditis elegans (C. elegans) Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. oocyte maturation from pachytene exit and MPK-1 (show MAPK1 Proteins) activation are redundantly controlled by the RBX-2-CUL-5 (show CUL5 Proteins)- and RBX-1-CUL-2 (show CUL2 Proteins)-based complexes.

Mouse (Murine) Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. Downregulation of Rbx1 caused accumulation of Emi1.

  2. a model by which N-terminal cleavage of RBX1 impairs its activity and promotes susceptibility to ER stress induction.

  3. Nrf2 regulates Cul3-Rbx1 by controlling regulation of expression and induction of Cul3-Rbx1

  4. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

  5. in vivo physiological function of RBX1 is to ensure cell proliferation by preventing p27 (show CDKN1B Proteins) accumulation during the early stage of embryonic development

Human Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. p97 (show EIF4G2 Proteins) negatively regulates NRF2 (show GABPA Proteins) through the canonical pathway by extracting ubiquitylated NRF2 (show GABPA Proteins) from the KEAP1 (show KEAP1 Proteins)-CUL3 (show CUL3 Proteins) E3 complex.

  2. Regulation of substrate ubiquitination and polyubiquitination takes place through Rbx1 rotations.

  3. High RBX1 expression was related to poor tumor differentiation, advanced TNM (show ODZ1 Proteins) stage, and lymph node metastasis in non-small cell lung cancer.

  4. Data show that melanoma antigen, family C, 2 protein (MAGE-C2) binds with RING-box protein 1 (Rbx1) and Cullin 1, and regulates cyclin E stability in melanoma cells.

  5. ROC1 (show RIT1 Proteins) has an important role in the malignant progression of bladder transitional cell carcinoma via the mTOR (show FRAP1 Proteins)/DEPTOR (show DEPTOR Proteins) pathway.

  6. Nedd8 (show NEDD8 Proteins)(Q40E) cannot induce the same structural effect on Cul1 (show CUL1 Proteins)-Rbx1 as wild-type Nedd8 (show NEDD8 Proteins).

  7. RBX1 E3 ubiquitin protein expression responsible with multiple genetic mechanism in the development of head and neck cancer.

  8. This work sheds new light on the roles of NEDD8 (show NEDD8 Proteins) lysines on neddylation cascades and provides a dominant negative mutant for the study of neddylation and its biological functions.

  9. These findings indicate that Rbx1 and Rbx2 (show RNF7 Proteins) can both activate Cul5 (show CUL5 Proteins)-Vif (show BTG1 Proteins) E3 ligase in vitro, but they may undergo a more delicate selection mechanism in vivo.

  10. upregulation of miR-194 can inhibit proliferation, migration, and invasion of GC cells, possibly by targeting RBX1. Aberrant expression of miR-194 and RBX1 is correlated to GC patient survival time.

Cow (Bovine) Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. The SCF (show KITLG Proteins)-complex gene expression has been characterized during bovine preimplantation development (show MTA2 Proteins).

RBX1 Protein Profile

Protein Summary

This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.

Alternative names and synonyms associated with RBX1

  • ring-box 1, E3 ubiquitin protein ligase (RBX1)
  • ring-box 1 (Rbx1)
  • ring-box 1, E3 ubiquitin protein ligase (Rbx1)
  • ring-box 1, E3 ubiquitin protein ligase (rbx1)
  • ring-box 1 (RBX1)
  • RING-box protein 1 (RBX1)
  • ring-box 1 (MGG_08844)
  • ring-box 1 (rbx1)
  • Protein RBX-1 (rbx-1)
  • 1500002P15Rik protein
  • AA517855 protein
  • ATRBX1 protein
  • BA554C12.1 protein
  • F7C8.160 protein
  • F7C8_160 protein
  • hop21 protein
  • HRT1 protein
  • im:7137515 protein
  • RBX1 protein
  • RING-box 1 protein
  • RNF75 protein
  • ROC1 protein
  • zgc:136444 protein

Protein level used designations for RBX1

E3 ubiquitin-protein ligase RBX1 , RING box protein 1 , RING finger protein 75 , RING-box protein 1 , ZYP protein , regulator of cullins 1 , ring-box protein 1 , ring-box 1 , hyperosmotic protein 21 , sHOP21

9978 Homo sapiens
56438 Mus musculus
300084 Rattus norvegicus
418001 Gallus gallus
449846 Danio rerio
458860 Pan troglodytes
474494 Canis lupus familiaris
518880 Bos taurus
832179 Arabidopsis thaliana
2679830 Magnaporthe oryzae 70-15
9308017 Arabidopsis lyrata subsp. lyrata
100528272 Ictalurus punctatus
100363742 Mus musculus
179358 Caenorhabditis elegans
100136424 Salmo salar
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