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Browse our RBX1 Proteins (RBX1)

Full name:
Ring-Box 1, E3 Ubiquitin Protein Ligase Proteins (RBX1)
On www.antibodies-online.com are 8 Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) Proteins from 4 different suppliers available. Additionally we are shipping RBX1 Antibodies (58) and many more products for this protein. A total of 67 RBX1 products are currently listed.
Synonyms:
1500002P15Rik, AA517855, BA554C12.1, hop21, RNF75, ROC1
list all proteins Gene Name GeneID UniProt
RBX1 56438 P62878
RBX1 9978 P62877
Rat RBX1 RBX1 300084  

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RBX1 Proteins (RBX1) by Origin

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Top referenced RBX1 Proteins

  1. Human RBX1 Protein expressed in Wheat germ - ABIN1317671 : Mallampalli, Glasser, Coon, Chen: Calmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis. in Cell cycle (Georgetown, Tex.) 2013 (PubMed)

More Proteins for RBX1 Interaction Partners

Caenorhabditis elegans (C. elegans) Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. oocyte maturation from pachytene exit and MPK-1 (show MAPK1 Proteins) activation are redundantly controlled by the RBX-2-CUL-5 (show CUL5 Proteins)- and RBX-1-CUL-2 (show CUL2 Proteins)-based complexes.

Mouse (Murine) Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. Downregulation of Rbx1 caused accumulation of Emi1.

  2. the early or pre-induction nuclear export of INrf2 (show KEAP1 Proteins) in response to antioxidants is controlled by tyrosine phosphorylation, whereas the nuclear export of Cul3 (show CUL3 Proteins) and Rbx1 is controlled by INrf2 (show KEAP1 Proteins), allowing normal activation or repression of Nrf2 (show NFE2L2 Proteins)

  3. a model by which N-terminal cleavage of RBX1 impairs its activity and promotes susceptibility to ER stress induction.

  4. Nrf2 regulates Cul3-Rbx1 by controlling regulation of expression and induction of Cul3-Rbx1

  5. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

  6. prothymosin-alpha (show PTMA Proteins)-mediated nuclear import of INrf2 (show KEAP1 Proteins)/Cul3 (show CUL3 Proteins) Rbx1 complex leads to ubiquitination and degradation of Nrf2 (show NFE2L2 Proteins) inside the nucleus presumably to regulate nuclear level of Nrf2 (show NFE2L2 Proteins) and rapidly switch off the activation of Nrf2 (show NFE2L2 Proteins) downstream gene expression.

  7. in vivo physiological function of RBX1 is to ensure cell proliferation by preventing p27 (show CDKN1B Proteins) accumulation during the early stage of embryonic development

Human Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. Data show that melanoma antigen, family C, 2 protein (MAGE-C2) binds with RING-box protein 1 (Rbx1) and Cullin 1, and regulates cyclin E stability in melanoma cells.

  2. ROC1 (show RIT1 Proteins) has an important role in the malignant progression of bladder transitional cell carcinoma via the mTOR (show FRAP1 Proteins)/DEPTOR (show DEPTOR Proteins) pathway.

  3. Nedd8 (show NEDD8 Proteins)(Q40E) cannot induce the same structural effect on Cul1 (show CUL1 Proteins)-Rbx1 as wild-type Nedd8 (show NEDD8 Proteins).

  4. RBX1 E3 ubiquitin protein expression responsible with multiple genetic mechanism in the development of head and neck cancer.

  5. This work sheds new light on the roles of NEDD8 (show NEDD8 Proteins) lysines on neddylation cascades and provides a dominant negative mutant for the study of neddylation and its biological functions.

  6. These findings indicate that Rbx1 and Rbx2 (show RNF7 Proteins) can both activate Cul5 (show CUL5 Proteins)-Vif (show BTG1 Proteins) E3 ligase in vitro, but they may undergo a more delicate selection mechanism in vivo.

  7. upregulation of miR-194 can inhibit proliferation, migration, and invasion of GC cells, possibly by targeting RBX1. Aberrant expression of miR-194 and RBX1 is correlated to GC patient survival time.

  8. RBX1 expression level was associated with the proliferation of gastric cancer.

  9. Studied the DNA-level mechanisms affecting KEAP1 (show KEAP1 Proteins)/CUL3 (show CUL3 Proteins)/RBX1 E3-ubiquitin ligase (show MUL1 Proteins) complex as a regulator of NRF2 (show GABPA Proteins) levels in ovarian cancer.

  10. eEF1A1 may mediate SAMHD1 turnover by targeting it to the proteosome for degradation through association with Cullin4A and Rbx1.

Cow (Bovine) Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) interaction partners

  1. The SCF (show KITLG Proteins)-complex gene expression has been characterized during bovine preimplantation development (show MTA2 Proteins).

RBX1 Protein Profile

Protein Summary

This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.

Alternative names and synonyms associated with RBX1

  • Protein RBX-1 (rbx-1)
  • ring-box 1 (Rbx1)
  • ring-box 1 (rbx1)
  • ring-box 1, E3 ubiquitin protein ligase (RBX1)
  • ring-box 1, E3 ubiquitin protein ligase (Rbx1)
  • 1500002P15Rik protein
  • AA517855 protein
  • BA554C12.1 protein
  • hop21 protein
  • RNF75 protein
  • ROC1 protein

Protein level used designations for RBX1

E3 ubiquitin-protein ligase RBX1 , RING finger protein 75 , ring-box protein 1 , RING-box protein 1 , hyperosmotic protein 21 , sHOP21 , RING box protein 1 , ZYP protein , regulator of cullins 1

GENE ID SPECIES
179358 Caenorhabditis elegans
56438 Mus musculus
100136424 Salmo salar
9978 Homo sapiens
474494 Canis lupus familiaris
518880 Bos taurus
300084 Rattus norvegicus
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