Browse our AGL Proteins (AGL)

Full name:
Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase Proteins (AGL)
On are 5 Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) Proteins from 3 different suppliers available. Additionally we are shipping AGL Antibodies (46) and AGL Kits (3) and many more products for this protein. A total of 58 AGL products are currently listed.
1110061O17Rik, 9430004C13Rik, 9630046L06Rik, AI850929, C77197, DDBDRAFT_0219237, DDBDRAFT_0234114, DDB_0219237, DDB_0234114, GDE
list all proteins Gene Name GeneID UniProt
Mouse AGL AGL 77559  
AGL 178 P35573
Rat AGL AGL 362029  

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AGL Proteins (AGL) by Origin

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Human Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) interaction partners

  1. The study identified 31 novel mutations and extended the mutation spectrum of AGL in Chinese patients with glycogen (show GYS1 Proteins) storage disease type III.

  2. Our study establishes HAS2 (show HAS2 Proteins)-mediated HA synthesis as a driver of growth of bladder cancer with low AGL and provides preclinical rationale for personalized targeting of HAS2 (show HAS2 Proteins)/HA signaling in patients with low amylo-alpha-1-6-glucosidase-4-alpha-glucanotransferase -expressing tumors.

  3. AGL loss causes high SHMT2 (show SHMT2 Proteins) expression and consequently increases glycine-dependent nucleotide synthesis leading to bladder cancer growth.

  4. Point mutations in AGL gene are associated with glycogen (show GYS1 Proteins) storage disease type IIIa in a Chinese family.

  5. AGL haplotype analyses suggested that c.1019delA and c.958+1G>A are founder mutations in Turkish patients, while p.R864X is a recurrent mutation.

  6. A homozygous frameshift deletion, c.4456delT, in exon 33 of the AGL gene in Inuit children determines the cause of glycogen (show GYS1 Proteins) storage disease type IIIa and confirms a founder effect.

  7. study identified 10 different mutations in 8 Korean Glycogen (show GYS1 Proteins) storage disease type III patients; 5 mutations are novel and include 1 nonsense (c.1461G>A, p.W487X), 3 splicing (c.293+4_293+6delAGT in IVS4, c.460+1G>T in IVS5, c.2682-8A>G in IVS21) and 1 missense mutation (c.2591G>C, p.R864P)

  8. Characterization of a novel homozygous single point mutation at the polypyrimidine tract of intron 21 of the AGL gene in two consanguineous siblings with glycogen (show GYS1 Proteins) storage disease type III.

  9. We found that most patients with macular telangiectasia-2 possess retinal autoantibodies, the most prevalent of which were directed against AGL, RBP3 (show E2F1 Proteins), and CK-B.

  10. A founder effect discovered amongst Tunisian patients with glycogen (show GYS1 Proteins) storage disease type III and a c.3216_3217delGA mutation in the AGL gene.

AGL Protein Profile

Protein Summary

This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.

Alternative names and synonyms associated with AGL

  • amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL)
  • glycogen debranching enzyme (agl)
  • glycogen debranching enzyme (Mmah_0764)
  • amylo-1,6-glucosidase, 4-alpha-glucanotransferase (Agl)
  • amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase (Agl)
  • 1110061O17Rik protein
  • 9430004C13Rik protein
  • 9630046L06Rik protein
  • AI850929 protein
  • C77197 protein
  • DDBDRAFT_0219237 protein
  • DDBDRAFT_0234114 protein
  • DDB_0219237 protein
  • DDB_0234114 protein
  • GDE protein

Protein level used designations for AGL

amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) , glycogen debranching enzyme , amylo-1, 6-glucosidase, 4-alpha-glucanotransferase , amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase , glycogen storage disease type III , glycogen debrancher , amylo-1,6-glucosidase, 4-alpha-glucanotransferase , Glycogen debrancher

469392 Pan troglodytes
517397 Bos taurus
8626162 Dictyostelium discoideum AX4
8982925 Methanohalophilus mahii DSM 5219
100126856 Sus scrofa
77559 Mus musculus
178 Homo sapiens
362029 Rattus norvegicus
479931 Canis lupus familiaris
100050695 Equus caballus
100009066 Oryctolagus cuniculus
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