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Mouse (Murine) Ccl12 Protein expressed in Escherichia coli (E. coli) - ABIN2666885
Sarafi, Garcia-Zepeda, MacLean, Charo, Luster: Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1. in The Journal of experimental medicine 1997
Show all 6 references for ABIN2666885
results provide evidence for a previously unrecognized role of IKKbeta (show IKBKB Proteins) in the regulation of the growth plate that is mediated through stimulation-independent downregulation of MCP-5 (show CMA1 Proteins) in the perichondrium.
tumours are characterized by expression of inflammatory chemokines (CCL2 (show CCL2 Proteins), CCL5 (show CCL5 Proteins), CCL7 (show CCL7 Proteins), CCL8 (show CCL8 Proteins), CCL12, CXCL9 (show CXCL9 Proteins), CXCL10 (show CXCL10 Proteins) and CX3CL1 (show CX3CL1 Proteins)), reflected by an enrichment of activated Foxp3 (show FOXP3 Proteins)(-) and Foxp3 (show FOXP3 Proteins)(+) T cells
After 100% O2 treatment, genes involved in inflammation (Ccl12), angiogenesis (Igfr1, Stat3 (show STAT3 Proteins)), and metabolism (Hk2 (show HK2 Proteins)) were upregulated.
Data indicate mRNA upregulation of CCR2 (show CCR2 Proteins) and CCR2 (show CCR2 Proteins) ligands CCL2 (show CCL2 Proteins), CCL7 (show CCL7 Proteins), CCL8 (show CCL8 Proteins), and CCL12 in aortas from DOCA/salt-treated hypertension.
The transforming growth factor (TGF)beta type II receptor (show TGFBR2 Proteins)/MCP-5 (show CMA1 Proteins) axis is an essential crossroad for joint development and endochondral growth.
CCL12 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli.
Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
chemokine (C-C motif) ligand 12
, C-C motif chemokine 12
, MCP-1-related chemokine
, monocyte chemoattractant protein 5
, monocyte chemotactic protein 5
, small inducible cytokine A12
, small-inducible cytokine A12