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Browse our anti-Chemokine (C-C Motif) Ligand 2 (CCL2) Antibodies

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anti-Chemokine (C-C Motif) Ligand 2 Antibodies (CCL2)
On are 530 Chemokine (C-C Motif) Ligand 2 (CCL2) Antibodies from 35 different suppliers available. Additionally we are shipping Chemokine (C-C Motif) Ligand 2 Kits (191) and Chemokine (C-C Motif) Ligand 2 Proteins (126) and many more products for this protein. A total of 869 Chemokine (C-C Motif) Ligand 2 products are currently listed.
AI323594, GDCF-2, HC11, HSMCR30, JE, MCAF, MCP-1, MCP-1A, MCP1, MCP1A, SCYA2, Sigje, SMC-CF

All available anti-Chemokine (C-C Motif) Ligand 2 Antibodies

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Top referenced anti-Chemokine (C-C Motif) Ligand 2 Antibodies

  1. Human Monoclonal CCL2 Primary Antibody for EIA - ABIN453918 : Matsushima, Larsen, DuBois, Oppenheim: Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. in The Journal of experimental medicine 1989 (PubMed)
    Show all 9 references for ABIN453918

  2. Mouse (Murine) Monoclonal CCL2 Primary Antibody for IHC (fro), IHC (p) - ABIN1108186 : Zoja, Liu, Donadelli, Abbate, Testa, Corna, Taraboletti, Vecchi, Dong, Rollins, Bertani, Remuzzi: Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice. in Journal of the American Society of Nephrology : JASN 1997 (PubMed)
    Show all 3 references for ABIN1108186

  3. Cow (Bovine) Polyclonal CCL2 Primary Antibody for EIA, WB - ABIN401066 : Liptak, Sullivan, Henkes, Wijayagunawardane, Miyamoto, Davis, Rueda, Townson: Cooperative expression of monocyte chemoattractant protein 1 within the bovine corpus luteum: evidence of immune cell-endothelial cell interactions in a coculture system. in Biology of reproduction 2005 (PubMed)
    Show all 3 references for ABIN401066

  4. Human Polyclonal CCL2 Primary Antibody for BP, ICC - ABIN446462 : Fet, Fiebeler, Klinge, Park, Barth, Thepen, Tolba: Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 (PubMed)
    Show all 2 references for ABIN446462

  5. Human Monoclonal CCL2 Primary Antibody for EIA, FACS - ABIN1108180 : Semple, Kossmann, Morganti-Kossmann: Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010 (PubMed)
    Show all 2 references for ABIN1108180

  6. Human Polyclonal CCL2 Primary Antibody for EIA, IHC (p) - ABIN452821 : Rollins, Morton, Ledbetter, Eddy, Shows: Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus. in Genomics 1991 (PubMed)
    Show all 2 references for ABIN452821

  7. Mouse (Murine) Polyclonal CCL2 Primary Antibody for Neut, WB - ABIN223560 : Lau, Liu, Pahlevan, Yuan, Khazaeli, Ni, Chan, Vaziri: Role of Nrf2 Dysfunction in Uremia-Associated Intestinal Inflammation and Epithelial Barrier Disruption. in Digestive diseases and sciences 2014 (PubMed)

  8. Dog (Canine) Polyclonal CCL2 Primary Antibody for IHC, WB - ABIN2792200 : Carulli, Spagnolo, Fonseca, Welsh, duBois, Black, Denton: Single-nucleotide polymorphisms in CCL2 gene are not associated with susceptibility to systemic sclerosis. in The Journal of rheumatology 2008 (PubMed)

  9. Human Polyclonal CCL2 Primary Antibody for WB - ABIN446454 : Xiang, Dong, Liu, Wang, Shi, Wei, Hu, Gong: Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 (PubMed)

  10. Human Polyclonal CCL2 Primary Antibody for FACS, IF - ABIN390653 : Bannon, Johnson, Michelhaugh, Hartley, Halter, David, Kapatos, Schmidt: A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 (PubMed)

More Antibodies against Chemokine (C-C Motif) Ligand 2 Interaction Partners

Human Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Results of the luciferase reporter gene assay demonstrated that miR-1 (show FSD1 Antibodies)-3p targeted CCL2. MiR-1 (show FSD1 Antibodies)-3p suppresses the proliferation and invasion of urinary bladder cancer cells by targeting CCL2.

  2. Low wall shear stress concomitant with turbulent flow contributes to sustained expression of MCP-1 in endothelial cells and presumably plays a role in facilitating macrophage infiltration and exacerbating inflammation, which leads to enlargement or rupture of intracranial aneurysms.

  3. MCP-1 is increased in endothelial cells after treatment with uremic toxins p-cresyl sulfate and indoxyl sulfate.

  4. Elevations in serum and follicular fluid MCP-1 levels are positively correlated with adiposity and negatively correlated with pregnancy rates in women undergoing IVF (show SCN5A Antibodies).

  5. Nurr1 (show NR4A2 Antibodies) overexpression exerts neuroprotective and anti-inflammatory roles via down-regulating CCL2 in both in vivo and in vitro Parkinson's disease models, contributing to developing mechanism-based and neuroprotective strategies against PD

  6. Study shows that MCP-1 -2518A/G polymorphism does not influence ischemic stroke risk

  7. IL-6 (show IL6 Antibodies) Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 (show CCL5 Antibodies) in Non-small Cell Lung Cancer

  8. Urinary CCL2:Cr/CXCL10 (show CXCL10 Antibodies):Cr alone have similar prognostic performance after kidney transplantation, but when both are elevated, this suggests a worse prognosis.

  9. Using a combination of cytokine expression profiling and miRNAs algorithms, we identified VEGFA (show VEGFA Antibodies)/CCL2 and FOXO3a (show FOXO3 Antibodies) as direct targets of miR-1 (show FSD1 Antibodies), miR (show MLXIP Antibodies)-206 and miR (show MLXIP Antibodies)-31, respectively. Importantly, systemic delivery of anti-VEGFA (show VEGFA Antibodies)/CCL2 or pre-miR-1 (show FSD1 Antibodies), pre-miR (show MLXIP Antibodies)-206 and anti-miR (show MLXIP Antibodies)-31 significantly inhibited tumor angiogenesis, TAMs accumulation, tumor growth and lung metastasis.

  10. calprotectin (show S100A8 Antibodies) induces IL-6 (show IL6 Antibodies) and MCP-1 production in Human Gingival Fibroblasts via TLR4 (show TLR4 Antibodies) signaling that involves MAPK (show MAPK1 Antibodies) and NF-kappaB (show NFKB1 Antibodies), resulting in the progression of periodontitis.

Mouse (Murine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Macrophages induce neural stem cells migrating into the spinal cord injury site possibly through promoting the secretion of MCP-1 (show CPT1B Antibodies).

  2. this study shows that CCL2 supports the classical activation of macrophages, with miR (show MLXIP Antibodies)-9 mediated down-regulation of Dusp6 (show DUSP6 Antibodies) and enhanced ERK (show EPHB2 Antibodies)-mediated signal transduction possibly mediating this enhanced pro-inflammatory gene expression

  3. macrophage-specific chemokine (C-C Motif) receptor 2 (Ccr2 (show CCR2 Antibodies)) knockout (M-Ccr2KO) and intestinal epithelial cell-specific tamoxifen-inducible Ccl2 knockout (Vil (show VIL1 Antibodies)-Ccl2KO) mice, were studied.

  4. PERK (show EIF2AK3 Antibodies) and IRE1alpha (show ERN1 Antibodies)/XBP1 (show XBP1 Antibodies) in the unfolded protein response differentially regulate the expression of CXCL10 (show CXCL10 Antibodies) and CCL2 likely through modulation of ER stress-induced NF-kappaB (show NFKB1 Antibodies) RelA (show NFkBP65 Antibodies) and STAT3 (show STAT3 Antibodies) activation.

  5. microRNA-155 promoted the directional migration of smooth muscle progenitor cells from the adventitia by regulating the monocyte chemoattractant protein 1 concentration gradient, which aggravated transplant arteriosclerosis.

  6. Kupffer cells secrete CCL2 to promote CCR2-expressing neutrophil recruitment from the bone marrow and subsequent infiltration into the liver during ischemia/reperfusion injury. These findings reveal a novel pro-inflammatory role of cell-mediated CCL2-CCR2 interactions during this sterile insult.

  7. IL-6 (show IL6 Antibodies) Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 (show CCL5 Antibodies) in Non-small Cell Lung Cancer

  8. this study shows that CCL2 ablation provides highly increased susceptibility to Japanese encephalitis virus

  9. Data show that loss of loss of matrix metalloproteinase-3 (MMP-3 (show MMP3 Antibodies)) repressed the upregulation of the chemokines monocyte chemoattractant protein (MCP)-1 (show CPT1B Antibodies) and (C-X-C motif) ligand 1 (CXCL1 (show CXCL1 Antibodies)).

  10. These data indicated that alpha7-nAChR (show CHRNA7 Antibodies) caused the inhibition of ASPinduced activation of p38 (show CRK Antibodies) kinase and NFkappa B to inhibit the production of MCP1 and keratinocytederived chemokine (show CCL1 Antibodies).

Cow (Bovine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes

  2. Studied SNPs in the bovine toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) and monocyte chemo attractant protein-1(CCL2) genes.

  3. The LEP (show LEP Antibodies), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.

  4. immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum

Rabbit Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (show CXCL12 Antibodies) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.

  2. In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.

  3. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (show IL8 Antibodies)) decreased significantly in Dachengqi decoction treatment group.

  4. measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.

  5. Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.

Pig (Porcine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. CXCL10 (show CXCL10 Antibodies) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  2. Porcine CCL2 binding on Tuk4+SLA (show SLA Antibodies)-II- but not on Tuk4-SLA (show SLA Antibodies)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.

  3. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  4. MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment

  5. Contrast media did not affect bone marrow cell viability/MCP-1 secretion.

  6. Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.

  7. in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta

  8. Variable gene expression (eg, matrix metalloproteinase-9 (show MMP9 Antibodies), CCL2 and Lp-PLA(2 (show Lp-PLA2 Antibodies)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.

  9. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (show F3 Antibodies) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (show CRP Antibodies)

Chemokine (C-C Motif) Ligand 2 (CCL2) Antigen Profile

Antigen Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Alternative names and synonyms associated with Chemokine (C-C Motif) Ligand 2 (CCL2)

  • chemokine (C-C motif) ligand 2 (CCL2) antibody
  • chemokine (C-C motif) ligand 2 (Ccl2) antibody
  • macrophage cationic peptide 1 (MCP-1) antibody
  • mast cell proteinase-1 (MCP1) antibody
  • AI323594 antibody
  • GDCF-2 antibody
  • HC11 antibody
  • HSMCR30 antibody
  • JE antibody
  • MCAF antibody
  • MCP-1 antibody
  • MCP-1A antibody
  • MCP1 antibody
  • MCP1A antibody
  • SCYA2 antibody
  • Sigje antibody
  • SMC-CF antibody

Protein level used designations for CCL2

small inducible cytokine A2 , C-C motif chemokine 2 , immediate-early serum-responsive JE protein , immediate-early serum-responsive protein JE , monocyte chemoattractant protein 1 , monocyte chemoattractant protein-1 , monocyte chemotactic protein 1 , small inducible gene JE , small-inducible cytokine A2 , monocyte chemotactic and activating factor , monocyte secretory protein JE , small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) , small inducible cytokine subfamily A (Cys-Cys), member 2 , platelet-derived growth factor-inducible protein JE , acidic seminal fluid protein , monocyte chemotactic protein 1A , MCP-1 , chemokine CCL2/MCP-1 , CS-III , NP-1 , antiadrenocorticotropin peptide III , corticostatin III , corticostatin-3 , macrophage antibiotic peptide MCP-1 , SMCP-1A , mast cell protease 1A

748205 Pan troglodytes
24770 Rattus norvegicus
6347 Homo sapiens
20296 Mus musculus
281043 Bos taurus
100009130 Oryctolagus cuniculus
397422 Sus scrofa
403981 Canis lupus familiaris
100135494 Cavia porcellus
100034136 Equus caballus
100172740 Pongo abelii
101120093 Ovis aries
574138 Macaca mulatta
100009115 Oryctolagus cuniculus
443546 Ovis aries
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