You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our CCL3 Proteins (CCL3)

Full name:
Chemokine (C-C Motif) Ligand 3 Proteins (CCL3)
On are 108 Chemokine (C-C Motif) Ligand 3 (CCL3) Proteins from 20 different suppliers available. Additionally we are shipping CCL3 Antibodies (279) and CCL3 Kits (94) and many more products for this protein. A total of 489 CCL3 products are currently listed.
AI323804, CCL3L1, CCL3L3, G0S19-1, LD78alpha, MIP-1-alpha, MIP-1a, MIP-1alpha, MIP1-(a), MIP1-alpha, Mip1a, Scya3
list all proteins Gene Name GeneID UniProt
CCL3 6348 P10147
CCL3 25542 P50229
CCL3 20302 P10855

Show all synonyms

CCL3 Proteins (CCL3) by Origin

Select your origin of interest

Top referenced CCL3 Proteins

  1. Mouse (Murine) CCL3 Protein expressed in Escherichia coli (E. coli) - ABIN2666878 : Cocchi, DeVico, Garzino-Demo, Arya, Gallo, Lusso: Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 8 references for ABIN2666878

  2. Human CCL3 Protein expressed in Escherichia coli (E. coli) - ABIN2666616 : Blum, Forsdyke, Forsdyke: Three human homologs of a murine gene encoding an inhibitor of stem cell proliferation. in DNA and cell biology 1991 (PubMed)
    Show all 6 references for ABIN2666616

  3. Mouse (Murine) CCL3 Protein expressed in Escherichia coli (E. coli) - ABIN1046684 : Davatelis, Tekamp-Olson, Wolpe, Hermsen, Luedke, Gallegos, Coit, Merryweather, Cerami: Cloning and characterization of a cDNA for murine macrophage inflammatory protein (MIP), a novel monokine with inflammatory and chemokinetic properties. in The Journal of experimental medicine 1988 (PubMed)
    Show all 3 references for ABIN1046684

  4. Mouse (Murine) CCL3 Protein expressed in Escherichia coli (E. coli) - ABIN1098426 : Brown, Zurawski, Mosmann, Zurawski et al.: A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of ... in Journal of immunology (Baltimore, Md. : 1950) 1989 (PubMed)
    Show all 2 references for ABIN1098426

  5. Human CCL3 Protein expressed in Escherichia coli (E. coli) - ABIN666794 : Guan, Wang, Norcross: Identification of human macrophage inflammatory proteins 1alpha and 1beta as a native secreted heterodimer. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN666794

  6. Human CCL3 Protein expressed in Wheat germ - ABIN1348408 : Baschuk, Wang, Watt, Halse, House, Bird, Strugnell, Trapani, Smyth, Andrews: NK cell intrinsic regulation of MIP-1? by granzyme M. in Cell death & disease 2014 (PubMed)

More Proteins for CCL3 Interaction Partners

Human Chemokine (C-C Motif) Ligand 3 (CCL3) interaction partners

  1. we demonstrate an association of CCL3 expression by CLL cells with increased numbers of CD3 (show CD3 Proteins)+ T cells and CD57 (show B3GAT1 Proteins)+ cells in the lymph node microenvironment, which may promote CLL cell survival and proliferation.

  2. The N termini of CC chemokines are shown to be involved in receptor binding and oligomerization. We also report an alternative CCL3 oligomer structure that reveals how conformational changes in CCL3 N termini profoundly alter its surface properties and dimer-dimer interactions to affect GAG binding and oligomerization. Such complexity in oligomerization and GAG binding enables intricate, physiologically relevant regulatio

  3. CCL3 promotes VEGF-A (show VEGFA Proteins) expression and angiogenesis in human osteosarcoma cells by down-regulating miR (show MLXIP Proteins)-374b expression via JNK (show MAPK8 Proteins), ERK (show EPHB2 Proteins), and p38 (show CRK Proteins) signaling pathways.

  4. The residues on the N-loop and beta-sheets of MIP-1a are close to both CCR1 and CCR5, and those in the C-terminal helix region are close to CCR5.

  5. CCL2 (show CCL2 Proteins), 3, 14 have roles in stimulating macrophage bone marrow homing, proliferation, and polarization in multiple myeloma

  6. An increased MIP-1alpha level in nasopharyngeal aspirates from patients with acute respiratory symptoms during the first wheezing episode caused by viral infections might predict recurrent wheezing.

  7. Tregs from subjects with established type 1 diabetes were impaired in their ability to produce CCL3 and CCL4 (show CCL4 Proteins).

  8. Pleural and serum MIP1a were lower in patients with lung cancer compared to lung metastasis, pneumonia, tuberculosis, and transudate pleural effusion.

  9. AEG-1 (show MTDH Proteins) mediates CCL3/CCR5-induced EMT (show ITK Proteins) development via both Erk1/2 and Akt (show AKT1 Proteins) signaling pathway in CM patients, which indicates CCL3/CCR5-AEG-1 (show MTDH Proteins)-EMT (show ITK Proteins) pathway could be suggested as a useful target to affect the progression of CM.

  10. The EP in TKA differed from EP in aseptically failed THA by lower CCL3 and DC-STAMP mRNA and protein expression. EP of all studied inflammatory and osteoclastogenic molecules were similar in knee and hip OA.

Mouse (Murine) Chemokine (C-C Motif) Ligand 3 (CCL3) interaction partners

  1. A marked increase of CCL3 mRNA expression was observed in inflamed paws, with CCL3 protein detected in neutrophils and macrophages by immunohistochemical experiments.

  2. CCL2 (show CCL2 Proteins)/CCL3 double-mutant animals are viable, fertile, and do not present with gross abnormalities. Cuprizone increased CCL3 expression in wild-type but not mutant mice. Cuprizone-induced demyelination, oligodendrocyte loss, and astrogliosis were significantly ameliorated in the cortex but not corpus callosum of chemokine (show CCL1 Proteins)-deficient animals.

  3. these data suggest that the chemokine (show CCL1 Proteins) CCL3 is an hippocampal neuromodulator able to regulate synaptic plasticity mechanisms involved in learning and memory functions.

  4. Ccl3 mRNAs increased within 5 h after injury in mouse cortical slices.

  5. Previous exposure to noninjurious ventilation induces a state of tolerance to ventilator-induced lung injury. Down regulation of the chemokine (show CCL1 Proteins) gene Ccl3 could be the mechanism responsible for this effect.

  6. the tissue fibrinolytic system contributes to the induction of macrophage recruitment and CCL3 at the bone injury site, thereby, leading to the enhancement of the repair process.

  7. APOE (show APOE Proteins) varepsilon4 genotype specifically modulates astrocyte secretion of potent microglial chemotactic agents, including CCL3

  8. The chemokines monocyte chemotactic protein 1 (MCP1 (show CCL2 Proteins)), MIP1alpha, MIP1beta (show CCL4 Proteins), interferon gamma (show IFNG Proteins)-induced protein 10 (IP-10 (show CXCL10 Proteins)), and eotaxin were induced in Saa1 (show SAA1 Proteins) TG mice.

  9. In experimental autoimmune encephalomyelitis there was a significant increase in activation of astrocytes with increased MIP-1alpha expression.

  10. Aged mice had similar levels of IL-1beta (show IL1B Proteins), TNF (show TNF Proteins), IFN-gamma (show IFNG Proteins), IL-17 (show IL17A Proteins), and granulocyte colony-stimulating factor (show CSF3 Proteins) following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9 (show CXCL9 Proteins), CXCL12 (show CXCL12 Proteins), CCL3, CCL4 (show CCL4 Proteins), CCL5 (show CCL5 Proteins), CCL11, and CCL17 (show CCL17 Proteins).

Chimpanzee Chemokine (C-C Motif) Ligand 3 (CCL3) interaction partners

  1. variation in the CCL18 (show CCL18 Proteins)-CCL3-CCL4 (show CCL4 Proteins) chemokine (show CCL1 Proteins) gene cluster influences HIV Type 1 transmission and AIDS disease progression

Rhesus Monkey Chemokine (C-C Motif) Ligand 3 (CCL3) interaction partners

  1. CCL3, CCL4 (show CCL4 Proteins) and CCL5 (show CCL5 Proteins) gene expression was evaluated in response to simian-human immunodeficiency virus (SHIV) infection in a rhesus macaque model.

  2. Stress decreased MIP-1alpha gene expression in both CeA (show CEACAM3 Proteins) lesioned and non-lesioned animals. But, the CeA (show CEACAM3 Proteins) lesions increased the tissue expression of MIP-1alpha mRNA prior to and after stress exposure.

CCL3 Protein Profile

Protein Summary

This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.

Alternative names and synonyms associated with CCL3

  • chemokine (C-C motif) ligand 3 (CCL3)
  • chemokine (C-C motif) ligand 3 (Ccl3)
  • AI323804 protein
  • CCL3L1 protein
  • CCL3L3 protein
  • G0S19-1 protein
  • LD78alpha protein
  • MIP-1-alpha protein
  • MIP-1a protein
  • MIP-1alpha protein
  • MIP1-(a) protein
  • MIP1-alpha protein
  • Mip1a protein
  • Scya3 protein

Protein level used designations for CCL3

C-C motif chemokine 3 , macrophage inflammatory protein 1 alpha , G0/G1 switch regulatory protein 19-1 , PAT 464.1 , SIS-beta , macrophage inflammatory protein 1-alpha , small inducible cytokine A3 (homologous to mouse Mip-1a) , tonsillar lymphocyte LD78 alpha protein , MIP-1-alpha , Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3) , small inducible cytokine A3 , small-inducible cytokine A3 , L2G25B , MIP-1 alpha , MIP1 (a) , SIS-alpha , TY-5 , heparin-binding chemotaxis protein , macrophage inflammatory protein-1alpha , chemokine (C-C motif) ligand 3-like 1 , CC chemokine ligand 3 , chemokine (C-C motif) ligand 3-like 3 , CCL3-like 1 , MIP-1alpha

100057909 Equus caballus
6348 Homo sapiens
25542 Rattus norvegicus
20302 Mus musculus
282170 Bos taurus
448787 Canis lupus familiaris
454592 Pan troglodytes
619514 Macaca mulatta
Selected quality suppliers for CCL3 Proteins (CCL3)
Did you look for something else?