CCL3 Protein (AA 24-92)
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- Target See all CCL3 Proteins
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 24-92
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Cell Migration Assay (CMA)
- Sequence
- SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
- Characteristics
- Recombinant Human CCL3 (MIP-1alpha)
- Purity
- > 97 % by SDS PAGE
- Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5
- Top Product
- Discover our top product CCL3 Protein
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Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 1-92) protein (GST tag)
CCL3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 23-92) protein (His tag)CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (Active) proteinCCL3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (GST tag)CCL3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 3 (CCL3) protein (His tag)CCL3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (Biotin)CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 27-92) protein (His tag)Crystallography grade CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)Crystallography grade CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Storage
- -20 °C,-80 °C
- Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Expiry Date
- 12 months
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- Target
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Alternative Name
- CCL3 (MIP-1alpha) (CCL3 Products)
- Background
- Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
- Molecular Weight
- 7.716 kDa
- UniProt
- P10147
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagy
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