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Browse our CXCL5 Proteins (CXCL5)

Full name:
Chemokine (C-X-C Motif) Ligand 5 Proteins (CXCL5)
On are 83 Chemokine (C-X-C Motif) Ligand 5 (CXCL5) Proteins from 14 different suppliers available. Additionally we are shipping CXCL5 Antibodies (164) and CXCL5 Kits (72) and many more products for this protein. A total of 326 CXCL5 products are currently listed.
AMCF-II, CXCL5, Cxcl6, ENA-78, GCP-2, LIX, Scyb5, Scyb6
list all proteins Gene Name GeneID UniProt
CXCL5 6374 P42830
CXCL5 20311 P50228
CXCL5 60665 P97885

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CXCL5 Proteins (CXCL5) by Origin

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Top referenced CXCL5 Proteins

  1. Human CXCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666977 : Walz, Burgener, Car, Baggiolini, Kunkel, Strieter: Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8. in The Journal of experimental medicine 1992 (PubMed)
    Show all 8 references for ABIN2666977

  2. Human CXCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666644 : Grommes, Soehnlein: Contribution of neutrophils to acute lung injury. in Molecular medicine (Cambridge, Mass.) 2011 (PubMed)
    Show all 8 references for ABIN2666644

  3. Mouse (Murine) CXCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666646 : Wuyts, DHaese, Cremers, Menten, Lenaerts, De Loof, Heremans, Proost, Van Damme: NH2- and COOH-terminal truncations of murine granulocyte chemotactic protein-2 augment the in vitro and in vivo neutrophil chemotactic potency. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 5 references for ABIN2666646

  4. Human CXCL5 Protein expressed in Escherichia coli (E. coli) - ABIN1046744 : Chang, McNinch, Basu, Simonet: Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene. in The Journal of biological chemistry 1994 (PubMed)
    Show all 3 references for ABIN1046744

  5. Mouse (Murine) CXCL5 Protein expressed in Escherichia coli (E. coli) - ABIN1046746 : Smith, Herschman: Glucocorticoid-attenuated response genes encode intercellular mediators, including a new C-X-C chemokine. in The Journal of biological chemistry 1995 (PubMed)
    Show all 3 references for ABIN1046746

  6. Human CXCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2003555 : Dawes, Calvo, Perkins, Paterson, Kiesewetter, Hobbs, Kaan, Orengo, Bennett, McMahon: CXCL5 mediates UVB irradiation-induced pain. in Science translational medicine 2011 (PubMed)
    Show all 2 references for ABIN2003555

More Proteins for CXCL5 Interaction Partners

Human Chemokine (C-X-C Motif) Ligand 5 (CXCL5) interaction partners

  1. CXCL5 plays a promoting role in glioma in autocrine- and paracrine-dependent manners.

  2. The expression of CXCL5 is up-regulated in osteosarcoma cells.

  3. CXCL5 expression in urine is related to bladder cancer TNM (show ODZ1 Proteins) stage, lymph node metastasis, tumor size, and tumor grade.

  4. ENA 78 plasma levels were correlated with Expanded Disability Status Scale scores in neuromyelitis optica (NMO) patients; elevated secretion of ENA 78 may be a critical step in neutrophil recruitment during the remission of NMO.

  5. CXCL5 expression is enriched in human atherosclerotic coronary artery. The CXCL5 variant might be a genetic risk factor for the susceptibility of CAD and the CXCL5 promoter -156 G/C C allele might be an independent predictor for CAD.

  6. Study shows that CXCL5 expression is elevated in positive correlation to bladder cancer grade and promotes cell migration and invasion via binding to its receptor CXCR2 (show CXCR2 Proteins).

  7. Analysis of monocultured dermal fibroblasts and keratinocytes revealed that only fibroblasts but not keratinocytes displayed up regulated CXCL5 levels after UV stimulation.

  8. There was an inverse correlation between DACH1 (show DACH1 Proteins) mRNA levels and CXCL5 in both lung cancer cell lines and human NSCLC tissues.

  9. High CXCL5 expression is associated with pediatric ulcerative colitis.

  10. the increased level of CXCL5 in tissue compartments, including the central nervous system of HIV-1-infected individuals might alter the inflammatory response through the infiltration of neutrophils into tissue compartment

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 5 (CXCL5) interaction partners

  1. IL-17RA (show IL17RA Proteins) regulates CXL-1 and 5 production in the lungs during the adaptive response.

  2. STAT3 (show STAT3 Proteins) is required for maximal OSM (show OSM Proteins)-induced CXCL5 expression.

  3. CXCL5 has a role in neutrophil recruitment in TH17-mediated glomerulonephritis

  4. Since adaptive villus growth occurs despite impaired CXCL5 expression and enhanced angiogenesis, this suggests that the growth of new blood vessels is not needed for resection-induced mucosal surface area expansion following massive SBR (show NXF1 Proteins).

  5. CXCL5 regulates pulmonary responses to infection and plays a central role in conferring clock control of inflammation.

  6. findings demonstrated that CXCL1 (show CXCL1 Proteins) and CXCL5 are increased in circulation with onset of T2D, are produced by islets under stress, and synergistically affect islet function, suggesting that these chemokines participate in pathogenesis of T2D.

  7. TLR2-induced epithelial-derived CXCL5 is critical for polymorphonuclear leukocyte-driven destructive inflammation in pulmonary tuberculosis.

  8. Our data suggest that the differential regulation of the chemokine CXCL5 between osteoblasts and endothelial cells upon FGF2 treatment is involved in Hematopoietic stem cell mobilization from the osteoblast niche or bone marrow to peripheral blood.

  9. CXCL5 modulated macrophage activation, increased expression of the cholesterol efflux regulatory protein ABCA1 (show ABCA1 Proteins), and enhanced cholesterol efflux activity in macrophages.

  10. The omentum is the main site of early neutrophil entry into the peritoneal cavity, where the action of CXCL5 synergizes with matrix metalloproteinases MMP-2 (show MMP2 Proteins) and -9 to promote neutrophil migration during the inflammatory process.

CXCL5 Protein Profile

Protein Summary

The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation.

Alternative names and synonyms associated with CXCL5

  • chemokine (C-X-C motif) ligand 5 (CXCL5)
  • chemokine (C-X-C motif) ligand 5 (Cxcl5)
  • AMCF-II protein
  • CXCL5 protein
  • Cxcl6 protein
  • ENA-78 protein
  • GCP-2 protein
  • LIX protein
  • Scyb5 protein
  • Scyb6 protein

Protein level used designations for CXCL5

chemokine (C-X-C motif) ligand 5 , C-X-C motif chemokine 5 , epithelial-derived neutrophil-activating protein 78 , neutrophil-activating peptide ENA-78 , neutrophil-activating protein 78 , small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78) , cytokine LIX , granulocyte chemotactic protein-2 , small inducible cytokine B subfamily, member 5 , small inducible cytokine subfamily B, member 15 , small-inducible cytokine B5 , CXC chemokine LIX , chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)

611927 Canis lupus familiaris
701697 Macaca mulatta
701946 Macaca mulatta
703222 Macaca mulatta
740377 Pan troglodytes
6374 Homo sapiens
20311 Mus musculus
60665 Rattus norvegicus
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