CXCL5 Protein (AA 37-110, partial) (His tag)

Catalog No. ABIN1046744

Product Details

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Protein Type: Recombinant

Protein Characteristics: AA 37-110, partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CXCL5 protein is labelled with His tag.

Application: ELISA

Sequence: AGPAAAVLRE LRCVCLQTTQ GVHPKMISNL QVFAIGPQCS KVEVVASLKN GKEICLDPEA PFLKKVIQKI LDGG

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

References

Corbett, Schmitt, Riess, Walz: "Characterization of the gene for human neutrophil-activating peptide 78 (ENA-78)." in: Biochemical and biophysical research communications, Vol. 205, Issue 1, pp. 612-7, (1995) (PubMed).

Power, Furness, Brawand, Wells: "Cloning of a full-length cDNA encoding the neutrophil-activating peptide ENA-78 from human platelets." in: Gene, Vol. 151, Issue 1-2, pp. 333-4, (1995) (PubMed).

Chang, McNinch, Basu, Simonet: "Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene." in: The Journal of biological chemistry, Vol. 269, Issue 41, pp. 25277-82, (1994) (PubMed).

Target Details

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Alternative Name: C-X-C motif chemokine 5 protein (CXCL5 Products)

Synonyms: ENA-78 Protein, SCYB5 Protein, Cxcl6 Protein, CXCL5 Protein, GCP-2 Protein, GCP2 Protein, SCYB6 Protein, AMCF-II Protein, LIX Protein, Scyb5 Protein, Scyb6 Protein, C-X-C motif chemokine ligand 5 Protein, C-X-C motif chemokine ligand 6 Protein, chemokine (C-X-C motif) ligand 5 Protein, C-X-C motif chemokine 5 Protein, CXCL5 Protein, Cxcl6 Protein, LOC701946 Protein, LOC703222 Protein, Cxcl5 Protein

Background: Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.

Molecular Weight: 12 kD

UniProt: P42830

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity