Browse our Fibronectin Proteins (FN1)

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Fibronectin 1 Proteins (FN1)
On www.antibodies-online.com are 18 Fibronectin 1 (FN1) Proteins from 6 different suppliers available. Additionally we are shipping Fibronectin Antibodies (194) and Fibronectin Kits (23) and many more products for this protein. A total of 240 Fibronectin products are currently listed.
Synonyms:
CIG, E330027I09, ED-B, fb80d10, FIBNEC, fibronectin, FINC, Fn, fn-1, FN1, fn2, FNZ, GFND, GFND2, LETS, MSF, wu:fb80d10
list all proteins Gene Name GeneID UniProt
FN1 2335 P02751
FN1 14268 P11276
Rat FN1 FN1 25661  

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Fibronectin Proteins (FN1) by Origin

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Top referenced Fibronectin Proteins

  1. Human Fibronectin Protein expressed in Human Cells - ABIN2002555 : Liu, Fedorov, Pollard, Lattman, Almo, Magnus: Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii. in Journal of structural biology 1998 (PubMed)
    Show all 6 references for 2002555

More Proteins for Fibronectin Interaction Partners

Zebrafish Fibronectin 1 (FN1) interaction partners

  1. Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.

  2. Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage

  3. Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.

  4. Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.

  5. reduction of fn1 function enables rescue of cardiac fusion in hand2 (show HAND2 Proteins) mutants

  6. Fibronectin regulates epithelial organization during myocardial migration in zebrafish.

Human Fibronectin 1 (FN1) interaction partners

  1. Fibronectin and Hepatocyte Growth Factor (show HGF Proteins) were shown to be produced by lung fibroblasts and, furthermore, to enhance malignant pleural mesothelioma cell migration and invasion

  2. Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1 (show WWC1 Proteins)), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3 (show CELSR3 Proteins)), NIPBL (show NIPBL Proteins) (Nipped (show RPL38 Proteins)-B-like), and FN1 (fibronectin 1).

  3. fibrillar fibronectin on this polymer, but not a globular conformation obtained on control polymers, promotes synergistic presentation of integrin-binding sites and bound bone morphogenetic protein 2 (BMP-2 (show BMP2 Proteins)), which enhances mesenchymal stem cell osteogenesis in vitro and drives full regeneration of a nonhealing bone defect in vivo at low GF concentrations.

  4. Fn plays a critical role in inflammasome-activated cells by amplifying caspase-1 (show CASP1 Proteins) activation and inducing inflammatory cell death.

  5. If the expression of Capon (show NOS1AP Proteins) is decreased, myeloma cells are adhered to fibronectin or bone marrow stromal cells (bone marrow mesenchymal stem cells). In addition, the sensitivity of the cell line to chemotherapeutic agents was reduced after silencing Capon (show NOS1AP Proteins) in the myeloma cell line which was adhered to bone marrow mesenchymal stem cells.

  6. C-terminal truncation of transglutaminase 2 (TG2 (show TGM2 Proteins)) reduces binding to the small intestinal extracellular matrix (ECM (show MMRN1 Proteins)) despite retained fibronectin (FN)-binding capacity.

  7. analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation

  8. In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (show ANGPT2 Proteins) Ang-1 (show ANGPT1 Proteins), but not the receptor binding domain of Ang-2 (show ANGPT2 Proteins), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (show MAPK1 Proteins) signaling in the presence of both Ang-1 (show ANGPT1 Proteins) and fibronectin

  9. Results directly implicate the heparin-binding sequence of the first type III repeat of fibrillar fibronectin (FNIII1) in realignment of stress fibers in HUVECs and, importantly, show that the matricryptic heparin-binding RWRPK sequence located in FNIII1 is required for the response.

  10. TGFbeta (show TGFB1 Proteins) elevated the expression of CamK (show CAMK4 Proteins) IIbeta and CamK (show CAMK4 Proteins) IIdelta, while siRNA silencing of those two subtypes significantly reduced TGFbeta (show TGFB1 Proteins)-mediated expression of collagen A1 and fibronectin 1.

Mouse (Murine) Fibronectin 1 (FN1) interaction partners

  1. fibronectin has a critical role in tissue morphogenesis and the development of tissue heterogeneities

  2. The aged stem cell niche in skeletal muscle contains reduced levels of FN, leading to detrimental consequences for the function and maintenance of muscle stem cells (MuSCs). FN is a preferred adhesion substrate for MuSCs and integrin-mediated signaling via focal adhesion kinase and the p38 MAPK (show MAPK14 Proteins) pathway is strongly de-regulated in MuSCs from aged mice because of insufficient attachment to the niche.

  3. analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation

  4. scleraxis was required for TGFbeta-induced fibronectin expression: TGFbeta lost its ability to induce fibronectin expression following scleraxis knockdown.

  5. The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 (show LGALS3 Proteins) as opposed to fibronectin.

  6. Thus, similarly to growth factor signaling, fibronectin matrix assembly during early development can be both autocrine and paracrine.

  7. These results suggest that the Rac1 regulation of the FN arrangement is involved in retinoic acid-induced cleft palate.

  8. Fibrillar cellular fibronectin supports platelet adhesion, activation, aggregation and procoagulant activity via the interplay of a series of receptors i.e. integrins alpha5beta1 and alphaIIbbeta3, the GPIb-V-IX complex, GPVI (show GP6 Proteins) and Toll-like receptor 4 (show TLR4 Proteins).

  9. Fn1 synthesized by the neural crest mediated morphogenesis of the aortic arch artery and differentiation of neural crest cells into vascular smooth muscle cells by regulating Notch (show NOTCH1 Proteins) signaling.

  10. A novel mechanism of transcriptional regulation of fibronectin through CREB (show CREB1 Proteins).

Cow (Bovine) Fibronectin 1 (FN1) interaction partners

  1. plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.

  2. Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (show TGFB1 Proteins) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.

  3. Putative function of fibronectin and its receptor (integrin alpha(5 (show ITGA5 Proteins))beta(1)) in male and female gametes during bovine fertilization in vitro.

  4. These results highlight a crucial role for caveolin-1 (show CAV1 Proteins) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.

  5. P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn

Horse (Equine) Fibronectin 1 (FN1) interaction partners

  1. The expression of extracellular matrix molecules fibronectin and osteopontin (show SPP1 Proteins) in vitreous and retina samples in autoimmune uveitis was investigated.

Pig (Porcine) Fibronectin 1 (FN1) interaction partners

  1. The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.

  2. The relationship between hyaluronan synthesis and levels of versican (show Vcan Proteins), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.

  3. fibronectin has a cryptic binding site for tenascin (show TNC Proteins)

Fibronectin (FN1) Protein Profile

Protein Summary

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Alternative names and synonyms associated with Fibronectin (FN1)

  • fibronectin 1 (FN1)
  • fibronectin 1 (fn1)
  • fibronectin 1 (Fn1)
  • CIG protein
  • E330027I09 protein
  • ED-B protein
  • fb80d10 protein
  • FIBNEC protein
  • fibronectin protein
  • FINC protein
  • Fn protein
  • fn-1 protein
  • FN1 protein
  • fn2 protein
  • FNZ protein
  • GFND protein
  • GFND2 protein
  • LETS protein
  • MSF protein
  • wu:fb80d10 protein

Protein level used designations for Fibronectin 1 Proteins (FN1)

fibronectin 1 , gene C , fibronectin , fn1l , nat , natter , fibronectin-like , cold-insoluble globulin , migration-stimulating factor , FN , cumulus cell-specific fibronectin 1 transcript , embryo-specific fibronectin 1 transcript , fibronectin ED-A- region , fibronectin variable region

GENE ID SPECIES
459926 Pan troglodytes
595087 Xenopus (Silurana) tropicalis
613269 Macaca mulatta
100005469 Danio rerio
100405983 Callithrix jacchus
100464134 Ailuropoda melanoleuca
100601303 Nomascus leucogenys
2335 Homo sapiens
396133 Gallus gallus
14268 Mus musculus
25661 Rattus norvegicus
280794 Bos taurus
403845 Canis lupus familiaris
100034189 Equus caballus
397620 Sus scrofa
100732865 Cavia porcellus
100328589 Oryctolagus cuniculus
397744 Xenopus laevis
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