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Browse our anti-IL-10 (IL10) Antibodies

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anti-Interleukin 10 Antibodies (IL10)
On are 674 Interleukin 10 (IL10) Antibodies from 37 different suppliers available. Additionally we are shipping IL-10 Kits (312) and IL-10 Proteins (179) and many more products for this protein. A total of 1190 IL-10 products are currently listed.

All available anti-IL-10 Antibodies

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Top referenced anti-IL-10 Antibodies

  1. Human Monoclonal IL-10 Primary Antibody for ELISA (Capture), FACS - ABIN967464 : Just, Abrams, Louie, Urbano, Wara, Nicholas, Stein, King: Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1. in The Journal of pediatrics 1995 (PubMed)
    Show all 8 references for ABIN967464

  2. Cow (Bovine) Polyclonal IL-10 Primary Antibody for IHC, ELISA - ABIN1582204 : Shi, Diez-Freire, Jun, Qi, Katovich, Li, Sriramula, Francis, Sumners, Raizada: Brain microglial cytokines in neurogenic hypertension. in Hypertension 2010 (PubMed)
    Show all 7 references for ABIN1582204

  3. Human Monoclonal IL-10 Primary Antibody for ELISA, IHC - ABIN4324436 : Sahoo, Dey, Maiti: pSiM24 is a novel versatile gene expression vector for transient assays as well as stable expression of foreign genes in plants. in PLoS ONE 2014 (PubMed)
    Show all 6 references for ABIN4324436

  4. Human Polyclonal IL-10 Primary Antibody for ELISA, IF (p) - ABIN672051 : Kou, Hu, Yao, Wang, Shen, Kang, Hong: Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 (PubMed)
    Show all 5 references for ABIN672051

  5. Human Monoclonal IL-10 Primary Antibody for FACS - ABIN4896009 : Schilling, Harasymczuk, Schuler, Egan, Whiteside: IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model. in Journal of molecular medicine (Berlin, Germany) 2012 (PubMed)
    Show all 3 references for ABIN4896009

  6. Human Polyclonal IL-10 Primary Antibody for EIA, FACS - ABIN952917 : Trajkov, Trajchevska, Arsov, Petlichkovski, Strezova, Efinska-Mladenovska, Sandevski, Spiroski: Association of 22 cytokine gene polymorphisms with tuberculosis in Macedonians. in The Indian journal of tuberculosis 2010 (PubMed)
    Show all 2 references for ABIN952917

  7. Human Polyclonal IL-10 Primary Antibody for EIA, Func - ABIN116099 : Roca, Di Paolo, Petruzzelli, Grandaliano, Ranieri, Schena, Gesualdo: Dexamethasone modulates interleukin-12 production by inducing monocyte chemoattractant protein-1 in human dendritic cells. in Immunology and cell biology 2007 (PubMed)
    Show all 2 references for ABIN116099

  8. Mouse (Murine) Monoclonal IL-10 Primary Antibody for FACS - ABIN118665 : Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. in Immunological reviews 1992 (PubMed)

  9. Human Monoclonal IL-10 Primary Antibody for ELISA, WB - ABIN1724633 : Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

  10. Human Monoclonal IL-10 Primary Antibody for ELISA, WB - ABIN151606 : Rho, Lampe: High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. in Journal of proteome research 2013 (PubMed)

More Antibodies against IL-10 Interaction Partners

Human Interleukin 10 (IL10) interaction partners

  1. In patients with cutaneous leishmaniasis, the A allele in TNFalpha (show TNF Antibodies)-308G/A SNP was found more frequently in individuals with asymptomatic infection (16% vs 7%), whereas the CC genotype in IL-10-819 C/T SNP was more frequent in patients with chronic disease (34% vs. 27% in asymptomatic individuals). No differences in allele frequencies for TLR4 (show TLR4 Antibodies) SNPs were found among groups.

  2. DC-derived IL-10 selects high-affinity CTL upon priming. Moreover, IL-10 preserves established CTL memory by enhancing IL-15 (show IL15 Antibodies)-dependent homeostatic proliferation. These combined effects on CTL priming and memory maintenance provide a plausible mechanism how IL-10 promotes CTL responses in humans.

  3. Our findings demonstrated a novel epigenetic mechanism of IL-10 dysregulation in inflammatory bowel disease. Down-regulation of KAT2B (show KAT2B Antibodies) may disrupt the innate and adaptive inflammatory responses due to the suppression of this crucial anti-inflammatory cytokine.

  4. Low IL10 expression is associated with atherosclerosis.

  5. polymorphisms in IL-10 gene (-819C>T and -592C>A), haplotypes (ACC (show ACACA Antibodies) and GTA) and serum level are significantly associated with risk of MetS (show ETV3 Antibodies). IL- 10 -819C>T and -592C>A polymorphic variants are also significantly associated with insulin (show INS Antibodies) level and homeostasis model assessment-insulin (show INS Antibodies) resistance in north Indian MetS (show ETV3 Antibodies) subjects.

  6. findings suggest that interleukin-10 -1082G/A polymorphism may play an important role in susceptibility to tuberculosis

  7. Our results from a large-scale population-based study suggest that there are differences in levels of adiponectin (show ADIPOQ Antibodies), IL-10 and IL-12 (show IL12A Antibodies) between neonates that later develop T1D compared to their healthy controls

  8. Interleukin 10 and interleukin 10 receptor (show IL10RB Antibodies) expression was also enriched in interferon gamma (show IFNG Antibodies)-expressing activated CD8 (show CD8A Antibodies)(+) T cells. Treatment of anti-CD3 (show CD3 Antibodies)/CD28 (show CD28 Antibodies)-stimulated, purified CD8 (show CD8A Antibodies)(+) T cells with interleukin 10 alone could significantly enhance CD8 (show CD8A Antibodies)(+) T cell survival, an effect dependent on interleukin 10 receptor (show IL10RB Antibodies) expression

  9. this study provides evidence that "normal" and neoplastic plasma cell responses integrate an immunosuppressive IL-10 response, which can serve as a counterbalancing mechanism to limit harmful antibody/immune complex-mediated inflammation in case of a strong plasma cell response

  10. IL-10 deficiency results in stable chromatin alterations in intestinal macrophages (IM), even in the absence of bacteria. This supports a model in which IL-10-deficiency leads to chromatin alterations that contribute to a loss of IM tolerance to bacteria, which is a primary initiating event in chronic intestinal inflammation.

Mouse (Murine) Interleukin 10 (IL10) interaction partners

  1. These results suggest that activation of iNKT cells increases the initial severity of C. albicans infection, most likely mediated by IL-10 induced modulation of macrophage antifungal activity.

  2. Our data suggest that NAOs have a beneficial preventive effect in septic shock correlated with the enhancement of IL-10 via the induction of A20 (show TNFAIP3 Antibodies) and COX-2 (show COX2 Antibodies).

  3. this study provides evidence that "normal" and neoplastic plasma cell responses integrate an immunosuppressive IL-10 response, which can serve as a counterbalancing mechanism to limit harmful antibody/immune complex-mediated inflammation in case of a strong plasma cell response.

  4. IL-10 deficiency results in stable chromatin alterations in intestinal macrophages (IM), even in the absence of bacteria. This supports a model in which IL-10-deficiency leads to chromatin alterations that contribute to a loss of IM tolerance to bacteria, which is a primary initiating event in chronic intestinal inflammation.

  5. Properdin (show CFB Antibodies) deficiency protects from 5-fluorouracil-induced small intestinal mucositis in a complement activation-independent, interleukin-10-dependent mechanism

  6. Data (including data from studies in knockout mice) suggest that up-regulation of signaling in colonic mucosa via interleukin-10/microRNA-155/SHIP-1 (Src homology 2 domain-containing inositol-5-phosphatase (show INPP5D Antibodies)) is involved in development of colitis due to dysbiosis.

  7. this study shows that a resident Escherichia coli that induces chronic colitis in IL-10-deficient mice rapidly but transiently activates the effector immune system in normal hosts, in parallel with induction of protective IL-10 produced by B cells and CD4 (show CD4 Antibodies)+ cells that subsequently suppresses this response to mediate mucosal homeostasis

  8. this study shows that pretreatment with sodium selenite prevents experimental colitis by restoring interleukin-10 excretion

  9. this paper shows that the ability of pVAXhsp65 vaccination to control experimental autoimmune encephalomyelitis development is associated with IL-10 induction

  10. Ellagic acid treatment augmented specific IL-10 production in response to S. mansoni antigenic stimulation. However, specific IL-1beta (show IL1B Antibodies), IL-4 (show IL4 Antibodies), IL-12 (show IL12A Antibodies), IL-13 (show IL13 Antibodies), IL-17A (show IL17A Antibodies), TNF-alpha (show TNF Antibodies) and IFN-gamma (show IFNG Antibodies) production were significantly reduced with ex vivo and in vivo ellagic acid treatment.

Cow (Bovine) Interleukin 10 (IL10) interaction partners

  1. This study seems to indicate that PGE2 in cattle does not produce an anti-inflammatory effect by increasing the synthesis of IL-10.

  2. IL-10 mRNA expression increased on day 8 in the mononuclear leukocytes of pregnant cows. In a cell culture experiment, interferon-tau stimulated stimulated IL-10 mRNA expression in mononuclear leukocytes.

  3. Bovine IL-10 potently inhibits the activation of human myeloid cells in response to toll (show TLR4 Antibodies) like receptor activation.

  4. Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 and SOCS-3 (show SOCS3 Antibodies), which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.

Horse (Equine) Interleukin 10 (IL10) interaction partners

  1. The ability of an EHV-1 isolate to down-regulate IL-10 production might contribute to increased local inflammation and a higher risk for neurological manifestation of the disease after infection with Ab4.

  2. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Antibodies) biased, interferon-gamma (show IFNG Antibodies) production is qualitatively similar to adult horses, and regulatory IL-10 production by T cells is mature.

  3. serum IL-6 (show IL6 Antibodies):IL-10 ratio is likely to provide a valuable prognosticator for neonatal septicemia

  4. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (show IL6 Antibodies), IL-10 and TNF-alpha (show TNF Antibodies), in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Guinea Pig Interleukin 10 (IL10) interaction partners

  1. The complete open reading frame consists of 537 base pairs which encodes a protein of 179 amino acids. This cDNA sequence exhibited 87% homology with human IL-10.

Rabbit Interleukin 10 (IL10) interaction partners

  1. ICAM1 (show ICAM1 Antibodies) and IL10 were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 (show JUN Antibodies) may be responsible for this upregulation.

Pig (Porcine) Interleukin 10 (IL10) interaction partners

  1. The PRRSV vaccination induced higher levels of IL-10 expression in the first week and this may be why the CSFV vaccination is immunosuppressed.

  2. These data indicate that the type 2 porcine reproductive and respiratory syndrome virus N protein plays an important role in IL-10 induction and the N-N non-covalent domain is associated with this activity.

  3. The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 Antibodies), IL-10, and IL-6 (show IL6 Antibodies) in ovarian follicles are reported.

  4. Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-gamma (show IFNG Antibodies)+CD4 (show CD4 Antibodies)+ regulatory T cells to control transplant arteriosclerosis.

  5. Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 production through p38 MAPK (show MAPK14 Antibodies) activation.

  6. Boar seminal plasma contained TGF- beta1 (show TGFB1 Antibodies) and IL-10 but with high individual variation.

  7. Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.

  8. These results suggest that TNF-alpha (show TNF Antibodies) and IL-10, but not IL-6 (show IL6 Antibodies), are involved in the late reparatory phases of the experimental disk lesion.

  9. The present study shows that elevated levels of serum CRP (show CRP Antibodies) and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS.(postweaning multisystemic wasting syndrome)

  10. Subclinically porcine circovirus type 2 (PCV2)-infected pigs developed a transient PCV2-specific IL-10 response during the viremic phase of infection which coincided with the inversion of the IgM/IgG ratio.

Rhesus Monkey Interleukin 10 (IL10) interaction partners

  1. IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS (show NTS Antibodies), which may contribute to differences in the clinical presentation of NTS (show NTS Antibodies) infection in the setting of malaria.

  2. Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis.

  3. IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha (show TNF Antibodies) cytokine production.

IL-10 (IL10) Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Alternative names and synonyms associated with IL-10 (IL10)

  • interleukin 10 (IL10) antibody
  • interleukin 10 (Il10) antibody
  • CSIF antibody
  • GVHDS antibody
  • Il-10 antibody
  • IL10A antibody
  • IL10X antibody
  • TGIF antibody

Protein level used designations for anti-Interleukin 10 (IL10) Antibodies

T-cell growth inhibitory factor , cytokine synthesis inhibitory factor , interleukin-10 , CSIF , IL-10 , uncharacterized protein LOC100715618 , Cytokine synthesis inhibitory factor , Interleukin-10

3586 Homo sapiens
16153 Mus musculus
25325 Rattus norvegicus
281246 Bos taurus
100034187 Equus caballus
443342 Ovis aries
403628 Canis lupus familiaris
428264 Gallus gallus
100860746 Capra hircus
100715618 Cavia porcellus
100008701 Oryctolagus cuniculus
397106 Sus scrofa
493683 Felis catus
694931 Macaca mulatta
100386149 Callithrix jacchus
469657 Pan troglodytes
101271889 Orcinus orca
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