Browse our LITAF Proteins (LITAF)

On are 9 Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF) Proteins from 5 different suppliers available. Additionally we are shipping LITAF Antibodies (88) and LITAF Kits (6) and many more products for this protein. A total of 110 LITAF products are currently listed.
3222402J11Rik, C85531, EET-1, N4WBP3, Pig7, SIMPLE, TBX1, TNF-alpha, TP53I7
list all proteins Gene Name GeneID UniProt
LITAF 9516 Q99732
LITAF 65161 P0C0T0
LITAF 56722 Q9JLJ0

LITAF Proteins (LITAF) by Origin

More Proteins for LITAF Interaction Partners

Human Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF) interaction partners

  1. Study conclude that LITAF is a monotopic membrane protein whose membrane integration is stabilised by a zinc finger. The related human protein, CDIP1 (cell death involved p53 target 1), displays identical membrane topology, suggesting that this mode of membrane integration is conserved in LITAF family proteins.

  2. PIG7 promotes leukemia cell chemosensitivity via lysosomal membrane permeabilization.

  3. Suggest LITAF as regulatory of pro-inflammatory and pro-fibrogenic pattern in non-alcoholic fatty liver disease.

  4. LITAF may serve as a switch in the balance between classical and alternative activation in tumor-associated inflammation. (Review)

  5. Results show that LITAF mutants in Charcot-Marie-Tooth 1C have an altered intracellular localization. They localize either completely or partially in the mitochondria depending on the mutation site. This can explain the different severity of the disease.

  6. Study shows that the I92V LITAF sequence variant would be a good candidate for a biomarker in the case of the CMT1A/HNPP (show PMP22 Proteins) disorders.

  7. The results of this study findings confirm that the genetic analysis of LITAF/SIMPLE should be considered for the diagnostic flow-chart of CMT1 patient, especially when nerve conduction studies show the presence of conduction blocks.

  8. Early-onset hereditary neuropathy with liability to pressure palsy (HNPP (show PMP22 Proteins)) was associated frequently with isoleucine92valine LITAF polymorphism.

  9. It is concluded that PA can induce insulin (show INS Proteins) resistance in liver cells and knockdown of LITAF expression can reduce insulin (show INS Proteins) resistance in liver cells.

  10. Mutation of SIMPLE (Litaf) in Charcot-Marie-Tooth 1C disease alters production of exosomes.

Mouse (Murine) Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF) interaction partners

  1. Suggest LITAF as regulatory of pro-inflammatory and pro-fibrogenic pattern in non-alcoholic fatty liver disease.

  2. Data suggest that atypical inflammatory signaling kinetics may account for the gain of function elicited by the Litaf protein SIMPLE mutation in Charcot-Marie-Tooth Type 1C (CMT1C) patients.

  3. Mutation of SIMPLE (Litaf) in Charcot-Marie-Tooth 1C alters production of exosomes.

  4. This study demonistrated that loss of Litaf function is unlikely to be a major contributor to Charcot-Marie-Tooth disease, but modulating effects of macrophages need to be considered in the etiology of the disease.

  5. In LITAF-deficient mice, mLITAF-mediated CCL2 (show CCL2 Proteins) production in macrophages was significantly reduced compared to the wild-type control animals

  6. Study provides evidence that LITAF contributes to the regulation of TNF-alpha (show TNF Proteins) in LPM harvested following acute inflammation.

  7. Whole-body deletion of LPS-induced TNF-alpha factor (LITAF) markedly improves experimental endotoxic shock and inflammatory arthritis.

  8. the regulation of LITAF/TNF-alpha by p53 (show TP53 Proteins) and its short peptide 162-motif

  9. PTP4A3 (show PTP4A3 Proteins) was identified as a novel negative regulator of LPS (show TLR4 Proteins)-induced LITAF/TNF-alpha production.

  10. LITAF is an important mediator of the LPS (show TLR4 Proteins)-induced inflammatory response.

LITAF Protein Profile

Protein Summary

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with LITAF

  • lipopolysaccharide-induced TNF factor (LITAF)
  • lipopolysaccharide-induced TNF factor (Litaf)
  • LPS-induced TN factor (Litaf)
  • 3222402J11Rik protein
  • C85531 protein
  • EET-1 protein
  • N4WBP3 protein
  • Pig7 protein
  • SIMPLE protein
  • TBX1 protein
  • TNF-alpha protein
  • TP53I7 protein

Protein level used designations for LITAF

LPS-induced TNF-alpha factor , lipopolysaccharide-induced TNF-alpha factor , lipopolysaccharide-induced tumor necrosis factor-alpha factor , p53-induced gene 7 protein , small integral membrane protein of lysosome/late endosome , tumor protein p53 inducible protein 7 , LPS-induced TN factor , LPS-induced TNF-alpha factor homolog , estrogen-enhanced transcript protein 1 , estrogen-responsive uterine transcript , lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog , TNF-alpha factor , lipid-induced TNF-alpha factor , tissue necrosis factor-alpha , LITAF-like protein , Nedd4 WW domain-binding protein 3 , estrogen-enhanced transcript protein , mEET

9516 Homo sapiens
65161 Rattus norvegicus
374125 Gallus gallus
56722 Mus musculus
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